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中国6省18~75岁人群高钙尿症检出情况及影响因素

张贝贝, 刘敏, 李园, 张普洪, 白雅敏, 吉宁, 吴静, 徐建伟. 中国6省18~75岁人群高钙尿症检出情况及影响因素[J]. 中华疾病控制杂志, 2022, 26(7): 766-770. doi: 10.16462/j.cnki.zhjbkz.2022.07.004
引用本文: 张贝贝, 刘敏, 李园, 张普洪, 白雅敏, 吉宁, 吴静, 徐建伟. 中国6省18~75岁人群高钙尿症检出情况及影响因素[J]. 中华疾病控制杂志, 2022, 26(7): 766-770. doi: 10.16462/j.cnki.zhjbkz.2022.07.004
ZHANG Bei-bei, LIU Min, LI Yuan, ZHANG Pu-hong, BAI Ya-min, JI Ning, WU Jing, XU Jian-wei. The detection of hypercalciuria and influencing factors among people aged 18-75 years old in six provinces of China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(7): 766-770. doi: 10.16462/j.cnki.zhjbkz.2022.07.004
Citation: ZHANG Bei-bei, LIU Min, LI Yuan, ZHANG Pu-hong, BAI Ya-min, JI Ning, WU Jing, XU Jian-wei. The detection of hypercalciuria and influencing factors among people aged 18-75 years old in six provinces of China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(7): 766-770. doi: 10.16462/j.cnki.zhjbkz.2022.07.004

中国6省18~75岁人群高钙尿症检出情况及影响因素

doi: 10.16462/j.cnki.zhjbkz.2022.07.004
基金项目: 

英国国立健康研究院资助中英减盐项目 16/136/77

详细信息
    通讯作者:

    徐建伟,E-mail: xujianwei@ncncd.chinacdc.cn

  • 中图分类号: R181

The detection of hypercalciuria and influencing factors among people aged 18-75 years old in six provinces of China

Funds: 

National Institute for Health Research Global Health Research Unit Action on Salt China 16/136/77

More Information
  • 摘要:   目的  了解中国6省18~75岁人群高钙尿症检出情况及影响因素。为预防高钙尿症及其引发的其他疾病提供依据。  方法  采用多阶段整群随机抽样方法,抽取中国6省18~75岁2 693名调查对象,开展问卷调查、体格检查并收集24 h尿标本,检测24小时尿钙水平(24-hours urinary calcium, 24HUC)。  结果  最终纳入分析2 637名研究对象,共检出高钙尿症者258名,高钙尿症检出率为9.78%,其中男性和女性高钙尿症检出率分别是8.47%和11.09%(χ2 =5.124, P=0.024)。多因素Logistic回归分析模型分析显示,女性(OR=1.366, 95% CI: 1.051~1.778, P=0.020)、45~<60岁(OR=2.069, 95% CI: 1.404~3.049, P < 0.001)、超重(OR=1.661, 95% CI: 1.216~2.268, P=0.001)、肥胖(OR=2.623, 95% CI: 1.855~3.709, P < 0.001)及患糖尿病(OR=1.988, 95% CI: 1.292~3.060, P=0.002)与高钙尿症的发生相关。  结论  中国人群高钙尿症检出率较高,建议重点人群应开展24HUC的筛查工作,及早预防高钙尿症及其引发的其他疾病。
  • 表  1  调查对象基本情况[n(%)]

    Table  1.   Basic characteristics of study population [n(%)]

    变量 男性(n=1 311) 女性(n=1 326) 合计(N=2 637)
    年龄(x±s, 岁) 49.00±12.85 47.06±12.59 48.02±12.75
    地区
      南部 522 (47.45) 578 (52.55) 1 100 (41.71)
      北部 789 (51.33) 748 (48.67) 1 537 (58.29)
    BMI(x±s, kg/m2) 24.85±3.55 24.68±3.64 24.76±3.60
    肥胖 244 (18.61) 223 (16.82) 467 (17.71)
    吸烟 751 (57.28) 40 (3.02) 791 (30.00)
    饮酒 830 (63.31) 249 (18.78) 1 079 (40.92)
    运动 543 (41.42) 522 (39.37) 1 065 (40.39)
    SBP(x±s, mm Hg) 129.96±17.49 122.83±20.22 126.37±19.24
    DBP(x±s, mm Hg) 82.20±11.71 76.88±10.89 79.52±11.61
    高血压 492 (37.53) 363 (27.38) 855 (32.42)
    糖尿病 89 (6.79) 87 (6.56) 176 (6.67)
    24HUC(x±s, mg) 169.66±93.72 149.90±81.73 159.72±88.43
    高钙尿症 111 (8.47) 147 (11.09) 258 (9.78)
    下载: 导出CSV

    表  2  不同特征人群高钙尿症检出率[n(%)]

    Table  2.   The detection rate of hypercalciuria in population with different characteristics[n(%)]

    特征 高钙尿症检出率 χ2 P 特征 高钙尿症检出率 χ2 P
    性别 5.124 0.024 运动 0.315 0.575
      男 111 (8.47)   是 100 (9.39)
      女 147 (11.09)   否 158 (10.05)
    年龄(岁) 19.055 < 0.001 高血压 0.79 0.374
      18~ < 45 37 (6.68)   是 90 (10.53)
      45~ < 60 128 (12.93)   否 168 (9.43)
      60~75 93 (8.52) 糖尿病 13.098 < 0.001
    地区 4.179 0.041   是 31 (17.61)
      南部 123 (11.18)   否 227 (9.22)
      北部 135 (8.78) BMI(kg/m2) 35.469 < 0.001
    吸烟 0.595 0.441   正常 74 (6.42)
      是 72 (9.10)   超重 110 (10.82)
      否 186 (10.08)   肥胖 74 (15.85)
    饮酒 0.209 0.647
      是 109 (10.10)
      否 149 (9.56)
    下载: 导出CSV

    表  3  高钙尿症影响因素Logistic回归分析模型分析

    Table  3.   Logistic regression analysis of influencing factors of hypercalciuria

    变量 β sx χ2 OR (95% CI)值 P
    性别
      男 1.000
      女 0.303 0.134 5.425 1.366(1.051~1.778) 0.020
    年龄(岁)
      60~75 1.000
      45~ < 60 0.727 0.198 13.495 2.069(1.404~3.049) < 0.001
      18~ < 45 0.390 0.208 3.514 1.477(0.982~2.221) 0.061
    BMI(kg/m2)
      正常 1.000
      超重 0.507 0.159 10.189 1.661(1.216~2.268) 0.001
      肥胖 0.964 0.177 29.745 2.623(1.855~3.709) < 0.001
    糖尿病
      否 1.000
      是 0.687 0.220 9.769 1.988(1.292~3.060) 0.002
    注:因变量为高钙尿症二分类变量;自变量为性别、年龄、地区、BMI、糖尿病。
    下载: 导出CSV
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出版历程
  • 收稿日期:  2021-10-27
  • 修回日期:  2022-03-23
  • 网络出版日期:  2022-07-19
  • 刊出日期:  2022-07-10

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