食管癌的流行病学及筛查研究进展

刘宇英; 魏君丽; 江柔; 伍民庆; 李艳红; 谢传波

doi:10.16462/j.cnki.zhjbkz.2022.07.016

食管癌的流行病学及筛查研究进展

doi: 10.16462/j.cnki.zhjbkz.2022.07.016

1.
510060 广州，中山大学肿瘤防治中心防癌体检健康管理中心
2.
450008 郑州，河南省肿瘤医院，郑州大学附属肿瘤医院健康管理中心

基金项目:

广东省医学科研基金 A2019469

详细信息

通讯作者:
谢传波，E-mail: xiechb@sysucc.org.cn

中图分类号: R735.1
计量
- 文章访问数: 954
- HTML全文浏览量: 293
- PDF下载量: 169
- 被引次数: 0
出版历程
- 收稿日期: 2022-03-18
- 修回日期: 2022-05-26
- 网络出版日期: 2022-07-19
- 刊出日期: 2022-07-10

Research progress on the epidemiology and screening of esophageal cancer

1.
Cancer Prevention Center, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
2.
Department of Health Care, Henan Cancer Hospital, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China

Funds:

Medical Research Fund of Guangdong Province A2019469

More Information

Corresponding author: XIE Chuan-bo, E-mail: xiechb@sysucc.org.cn

摘要

摘要: 食管癌是严重威胁中国居民健康的恶性肿瘤之一，中国是食管癌的高发地区，疾病负担严重。吸烟、饮酒、蔬菜水果摄入过少、不良饮食方式、感染、遗传因素均会增加食管癌的发生风险。虽然近年来液体活检技术显示出了良好的食管癌筛查效果，但是胃镜检查目前仍然是食管癌的标准筛查手段。中国早期食管癌诊断率偏低、筛查力度有待加强。
- 食管癌 /
- 流行病学 /
- 筛查
Abstract: Esophageal cancer is one of the malignant tumors that seriously threaten the health of Chinese residents. China is among the belt of esophageal cancer high incident areas and has a heavy burden of esophageal cancer. Smoking, alcohol, low fruit and vegetable intake, bad eating habits, infectious, and genetic reasons are risk factors for esophageal cancer. Although liquid biopsy technology has shown high accuracy for esophageal cancer screening, endoscopy is still the standard method for screening esophageal cancer. The Chinese population had a low screening rate for esophageal cancer and more efforts should be paid to improve the screening rate.
- Esophageal cancer /
- Epidemiology /
- Screening

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参考文献(35)

[1]	Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249. DOI: 10.3322/caac.21660.
[2]	刘宗超, 李哲轩, 张阳, 等. 2020全球癌症统计报告解读[J]. 肿瘤综合治疗电子杂志, 2021, 7(2): 1-14. DOI: 10.12151/JMCM.2021.02-01. Liu ZC, Li ZX, Zhang Y, et al. Interpretation on the report of global cancer statistics 2020[J]. Journal of Multidisciplinary Cancer Management (Electronic Version), 2021, 7(2): 1-14. DOI: 10.12151/JMCM.2021.02-01.
[3]	Thrift AP, Whiteman DC. The incidence of esophageal adenocarcinoma continues to rise: analysis of period and birth cohort effects on recent trends[J]. Ann Oncol, 2012, 23(12): 3155-3162. DOI: 10.1093/annonc/mds181.
[4]	Yang S, Lin S, Li N, et al. Burden, trends, and risk factors of esophageal cancer in China from 1990 to 2017: an up-to-date overview and comparison with those in Japan and South Korea[J]. J Hematol Oncol, 2020, 13(1): 146. DOI: 10.1186/s13045-020-00981-4.
[5]	Oze I, Matsuo K, Ito H, et al. Cigarette smoking and esophageal cancer risk: an evaluation based on a systematic review of epidemiologic evidence among the Japanese population[J]. Jpn J Clin Oncol, 2012, 42(1): 63-73. DOI: 10.1093/jjco/hyr170.
[6]	Wang QL, Xie SH, Li WT, et al. Smoking cessation and risk of esophageal cancer by histological type: systematic review and meta-analysis[J]. J Natl Cancer Inst, 2017, 109(12). DOI: 10.1093/jnci/djx115.
[7]	Yu X, Chen J, Jiang W, et al. Alcohol, alcoholic beverages and risk of esophageal cancer by histological type: a dose-response Meta-analysis of observational studies[J]. Alcohol Alcohol, 2020, 55(5): 457-467. DOI: 10.1093/alcalc/agaa047.
[8]	Castro C, Peleteiro B, Lunet N. Modifiable factors and esophageal cancer: a systematic review of published meta-analyses[J]. J Gastroenterol, 2018, 53(1): 37-51. DOI: 10.1007/s00535-017-1375-5.
[9]	Liu J, Wang J, Leng Y, et al. Intake of fruit and vegetables and risk of esophageal squamous cell carcinoma: a meta-analysis of observational studies[J]. Int J Cancer, 2013, 133(2): 473-485. DOI: 10.1002/ijc.28024.
[10]	Freedman ND, Park Y, Subar AF, et al. Fruit and vegetable intake and esophageal cancer in a large prospective cohort study[J]. Int J Cancer, 2007, 121(12): 2753-2760. DOI: 10.1002/ijc.22993.
[11]	Wang A, Zhu C, Fu L, et al. Citrus fruit intake substantially reduces the risk of esophageal cancer: a meta-analysis of epidemiologic studies[J]. Medicine (Baltimore), 2015, 94(39): e1390. DOI: 10.1097/MD.0000000000001390.
[12]	Yan B, Zhang L, Shao Z. Consumption of processed and pickled food and esophageal cancer risk: a systematic review and meta-analysis[J]. Bull Cancer, 2018, 105(11): 992-1002. DOI: 10.1016/j.bulcan.2018.08.006.
[13]	Dobo KL, Kenyon MO, Dirat O, et al. Practical and science-based strategy for establishing acceptable intakes for drug product N-nitrosamine impurities[J]. Chem Res Toxicol, 2022, 35(3): 475-489. DOI: 10.1021/acs.chemrestox.1c00369.
[14]	Wiseman M. The second world cancer research fund/American institute for cancer research expert report. Food, nutrition, physical activity, and the prevention of cancer: a global perspective[J]. Proc Nutr Soc, 2008, 67(3): 253-256. DOI: 10.1017/S002966510800712X.
[15]	Onuk MD, Oztopuz A, Memik F. Risk factors for esophageal cancer in eastern Anatolia[J]. Hepatogastroenterology, 2002, 49(47): 1290-1292.
[16]	Andrici J, Eslick GD. Hot food and beverage consumption and the risk of esophageal cancer: a meta-analysis[J]. Am J Prev Med, 2015, 49(6): 952-960. DOI: 10.1016/j.amepre.2015.07.023.
[17]	Lin S, Xu G, Chen Z, et al. Tea drinking and the risk of esophageal cancer: focus on tea type and drinking temperature[J]. Eur J Cancer Prev, 2020, 29(5): 382-387. DOI: 10.1097/CEJ.0000000000000568.
[18]	Petrelli F, De Santi G, Rampulla V, et al. Human papillomavirus (HPV) types 16 and 18 infection and esophageal squamous cell carcinoma: a systematic review and meta-analysis[J]. J Cancer Res Clin Oncol, 2021, 147(10): 3011-3023. DOI: 10.1007/s00432-021-03738-9.
[19]	Geng H, Xing Y, Zhang J, et al. Association between viral infection other than human papillomavirus and risk of esophageal carcinoma: a comprehensive meta-analysis of epidemiological studies[J]. Arch Virol, 2022, 167(1): 1-20. DOI: 10.1007/s00705-021-05268-8.
[20]	Islami F, Kamangar F. Helicobacter pylori and esophageal cancer risk: a meta-analysis[J]. Cancer Prev Res (Phila), 2008, 1(5): 329-338. DOI: 10.1158/1940-6207.CAPR-08-0109.
[21]	Ji J, Hemminki K. Familial risk for esophageal cancer: an updated epidemiologic study from Sweden[J]. Clin Gastroenterol Hepatol, 2006, 4(7): 840-845. DOI: 10.1016/j.cgh.2006.03.005.
[22]	潘恩春, 孙中明, 何源, 等. 沿淮河食管癌高发区居民家族遗传与食管癌发病风险的关系[J]. 现代预防医学, 2016, 43(14): 2524-2526. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF201614007.htm Pan EC, Sun ZM, He Y, et al. The correlation between the risk of esophagus cancer and familial inheritance of residents in the high-incidence area along the Huaihe River[J]. Modern Preventive Medicine, 2016, 43(14): 2524-2526. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF201614007.htm
[23]	蔡宁, 刘振球, 索晨, 等. 食管癌遗传易感基因多态性的研究进展[J]. 癌症进展, 2018, 16(11): 1331-1334. DOI: 10.11877/j.issn.1672-1535.2018.16.11.03. Cai N, Liu ZQ, Suo C, et al. Research progress of genetic susceptibility gene polymorphism in esophageal cancer[J]. Oncology Progress, 2018, 16(11): 1331-1334. DOI: 10.11877/j.issn.1672-1535.2018.16.11.03.
[24]	Ma L, Lan B, Guo L, et al. GSTM1 and GSTT1 gene polymorphisms, gene-gene interaction, and esophageal carcinoma risk: evidence from an updated meta-analysis[J]. Genet Test Mol Biomarkers, 2018, 22(1): 11-19. DOI: 10.1089/gtmb.2017.0137.
[25]	王贵齐, 魏文强. 上消化道癌筛查和早诊早治项目的新转变: 机会性筛查[J]. 中华预防医学杂志, 2019, 53(11): 1084-1085. DOI: 10.3760/cma.j.issn.0253-9624.2019.11.002. Wang GQ, Wei WQ. A new transition of the screening, early diagnosis and early treatment project of the upper gastrointestinal cancer: opportunistic screening[J]. Chin J Prev Med, 2019, 53(11): 1084-1085. DOI: 10.3760/cma.j.issn.0253-9624.2019.11.002.
[26]	国家消化内镜专业质控中心, 国家消化系统疾病临床医学研究中心(上海), 国家消化道早癌防治中心联盟, 等. 中国早期食管癌及癌前病变筛查专家共识意见(2019年, 新乡)[J]. 中华健康管理学杂志, 2019, 13(6): 465-473. DOI: 10.3760/cma.j.issn.1007-5232.2019.11.001. National Quality Control Center of Digestive Endoscopy, National Clinical Research Center for Digestive Diseases (Shanghai), National Early Gastrointestinal-Cancer Prevention & Treatment Center Alliance (GECA), et al. Expert consensus view for early stage esophageal cancer and precancerous lesions screening in Chiense population (2019, Xinxiang)[J]. Chin J Health Manage, 2019, 13(6): 465-473. DOI: 10.3760/cma.j.issn.1007-5232.2019.11.001.
[27]	Yang J, Wei WQ, Niu J, et al. Cost-benefit analysis of esophageal cancer endoscopic screening in high-risk areas of China[J]. World J Gastroenterol, 2012, 18(20): 2493-2501. DOI: 10.3748/wjg.v18.i20.2493.
[28]	郭鑫, 陈群清. 液体活检技术在食管癌诊治中的研究进展[J]. 广东医学, 2017, 38(15): 2400-2402. doi: 10.3969/j.issn.1001-9448.2017.15.043 Guo X, Chen QQ. Research progress of liquid biopsy technique in diagnosis and treatment of esophageal cancer[J]. Guangdong Medical Journal, 2017, 38(15): 2400-2402. doi: 10.3969/j.issn.1001-9448.2017.15.043
[29]	高飞飞. 食管鳞状细胞癌患者外周血中循环肿瘤细胞的检测和临床意义[D]. 石家庄: 河北医科大学, 2012. Gao FF. Detection and clinical significance of circulatingtumor cells in peripheral blood of the patients with esophageal squamous cell carcinoma[D]. Shijiazhuang: Hebei Medical University, 2012.
[30]	Shi Y, Ge X, Ju M, et al. Circulating tumor cells in esophageal squamous cell carcinoma - mini review[J]. Cancer Manag Res, 2021, 13: 8355-8365. DOI: 10.2147/CMAR.S337489.
[31]	Niu C, Zhao L, Guo XD, et al. Diagnostic accuracy of circRNAs in esophageal cancer: a meta- analysis[J]. Dis Markers, 2019: 9673129. DOI: 10.1155/2019/9673129.
[32]	Hoshino I, Ishige F, Iwatate Y, et al. Cell-free microRNA-1246 in different body fluids as a diagnostic biomarker for esophageal squamous cell carcinoma[J]. PLoS One, 2021, 16(3): e248016. DOI: 10.1371/journal.pone.0248016.
[33]	Miyoshi J, Zhu Z, Luo A, et al. A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study[J]. Mol Cancer, 2022, 21(1): 44. DOI: 10.1186/s12943-022-01507-x.
[34]	Visaggi P, Barberio B, Gregori D, et al. Systematic review with meta-analysis: artificial intelligence in the diagnosis of oesophageal diseases[J]. Aliment Pharmacol Ther, 2022, 55(5): 528-540. DOI: 10.1111/apt.16778.
[35]	Luo H, Xu G, Li C, et al. Real-time artificial intelligence for detection of upper gastrointestinal cancer by endoscopy: a multicentre, case-control, diagnostic study[J]. Lancet Oncol, 2019, 20(12): 1645-1654. DOI: 10.1016/S1470-2045(19)30637-0.