Epidemiological advance of middle east respiratory syndrome coronavirus infection
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摘要: 中东呼吸综合征冠状病毒(middle east respiratory syndrome coronavirus,MERS-CoV)能引起人的下呼吸道感染,病死率高,对全球公共卫生造成了威胁。从2012年发现MERS-CoV至今,已经有26个国家出现过MERS-CoV病毒感染,截至2016年2月19日WHO报告的实验室确诊病例有1 638例,其中死亡病例587例。本综述对MERS-CoV的一般病毒学特点、致病机制进行了阐述,同时对MERS-CoV与严重急性呼吸系统综合征冠状病毒的流行病学特点进行了比较。Abstract: The middle east respiratory syndrome coronavirus (MERS-CoV) causes a severe lower respiratory tract infection in humans with high mortality, it has posed a serious global thereat to the public health. Since its discovery in 2012, MERS-CoV has reached 26 countries, as of 19 February 2016 WHO has been notified of 1 638 laboratory-confirmed cases of infection with MERS-CoV, including at least 587 related death. In this review, we highlighted the knowledge on MERS-CoV in general virology and mechanism of pathogeny, and compared MERS-CoV with SARS-CoV on the epidemiology.
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Key words:
- SARS virus /
- Coronavirus /
- Epidemiology /
- Middle east respiratory syndrome
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