Risk factors of degree of cerebral artery stenosis in patients with ischemic vascular disease
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摘要: 目的 探讨常见的缺血性脑血管狭窄严重程度的影响因素。方法 将160例行脑血管造影术检查的缺血性脑血管病患者按血管狭窄严重程度分成轻、中、重度狭窄三组,采用多元Logistic回归进行分析,寻找引起脑动脉狭窄严重程度的影响因素。结果 年龄、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)、糖尿病、高血压、同型半胱氨酸(homocysteine, Hcy)水平在不同程度狭窄组中比较差异具有统计学意义(均有P<0.05),其中年龄和LDL-C在重度狭窄组高于中度狭窄和轻度狭窄组(均有P<0.05),Hcy在重度狭窄组高于轻度狭窄组(P<0.05);Logistic回归分析发现年龄(OR=0.061, P<0.001)及高血脂(OR=0.435, P=0.003)是血管狭窄程度的危险因素;相对于糖尿病患者,非糖尿病者是血管狭窄程度的保护因素(OR=-0.821, P=0.009)。结论 年龄、高血脂是血管狭窄程度的危险因素,而非糖尿病则是保护因素。
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