Cross-sectional study on the relationship between dietary selenium intake and hypertension
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摘要: 目的 探讨膳食硒摄入量与高血压的关系。方法 从湖南湘雅医院健康体检中心随机选取被体检人员为研究对象,测量身高、体重、血压等身体指标,利用食物频率调查问卷间接测量膳食硒摄入情况。采用t检验、χ2检验进行单因素分析,Logistic回归模型分析膳食硒与高血压的关系。结果 分析显示,性别、年龄、体质指数、糖尿病患病情况及膳食纤维摄入情况在高血压患者与非高血压患者间的差异均有统计学意义(均有P<0.05)。校正年龄、性别、吸烟、饮酒状况等相关因素后,结果显示:以硒摄入水平的最低分类(<27.51 mg/d)作为参照,最高分类(>55.81 mg/d)的OR(95% CI)为0.715(0.528~0.968),高血压的患病率随着膳食硒摄入水平的升高而降低。结论 增加膳食硒摄入可以降低高血压的患病风险。Abstract: Objective To examine the association between selenium intake and hypertension in elderly population. Methods Participants from XiangYa hospital were randomly selected. The intake of selenium and other dairy consumption were evaluated by using a food frequency questionnaire, and the height, weight and blood pressure also measured. t-test and Chi-square test were used in univariate analysis, and Logistic regression model performed to analyze the relationship between the dietary selenium intake and hypertension. Results The results showed that there were significant differences(all P<0.05)between the hypertension and non-hypertension population groups in terms of sex, age, body mass index, diabetic and dietary fiber intake. After adjusting for age, gender, alcohol consumption, smoking status, etc, multiple Logistic regression model showed that there was a decrease trend in the risk of hypertension (OR =0.715,95% CI:0.528-0.968)between the level of selenium intake(>55.81 mg/d) and the risk of hypertension compared to the level of selenium intake(<27.51 mg/d).Conclusions These findings indicate that higher selenium intake might reduce the risk of hypertension.
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Key words:
- Selenium /
- Diet /
- Hypertension /
- Cross-sectional studies
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