Abstract: Objective To find out the epidemiological characteristics of tuberculosis in floating population in Liaoning province and explore more reasonable measures for prevention and control of tuberculosis by analyzing the data of tuberculosis patients in floating population in Liaoning province from 2006 to 2015. Methods The medical data of tuberculosis patients in the cities of Liaoning province from 2006 to 2015 were collected and analyzed. The related characteristics of tuberculosis patients in floating population were analyzed. Results There were 8 369 cases of migrant population registered in Liaoning province from 2006 to 2015. Percentage of the registered patients with the floating population in total registered patients was increasing yearly (χ_trend²=112.90, P<0.001). The tuberculosis floating patients among different provinces accounted for 74.53% of the total number of floating population patients. The patients were concentrated during the 15-44 years old age group. 68.07% of the floating patients were concentrated in Dalian, but the proportion of Shenyang (χ_trend²=122.55, P<0.001) and Anshan (χ_trend²=11.51, P=0.001) increased year by year. Most patients were the household chores and unemployed. There is an upward trend (χ_trend²=498.41, P<0.001). In terms of patient origin, the proportion of patients with treatment was increased significantly (χ_trend²=141.85, P<0.001). Conclusions Epidemiologic characteristics of tuberculosis patients in floating population are more diversified. The prevention and control can be strengthened by expanding the scope of education, improving the cross-regional management system, strengthening health screening, increasing the rate of participating insurance and giving incentives.