Abstract: Objective To explore the changes of blood pressure and quality of life in elderly hypertensive patients in Nanjing under community comprehensive health management. Methods From March to December 2013, 520 elderly hypertensive patients aged over 60 years were recruited from a community hospital in Nanjing, and were divided into the control group and the management group according to the principle of simple random assignment. The management group of elderly patients with hypertension had the special community health management, but the control group of elderly patients with hypertension had no intervention measures. A total of three surveys with questionnaires were conducted at baseline, mid (at the 6 months), and final periods (at the 18 months), and then used the multilevel model to analyze the change of quality of life. Results There were no significant differences in the baseline data between the management group and the control group (all P>0.05). After the 18 months of intervention, when management group compared to control group, the mean reduction of systolic pressure was (4.74±1.69)mm Hg (t=2.801, P=0.006), mean reduction of diastolic pressure was (3.67±1.17)mm Hg (t=3.158, P=0.002). The difference was statistically significant; In addition,the two groups had significant differences in vision situation (Z=-3.142, P=0.002), teeth status (Z=-2.130, P=0.034), sleep status (Z=-3.471, P<0.001), mental status (Z=-2.051, P=0.040) and total score of quality of life (Z=-2.653, P=0.008). All of them in management group was better than that of the control group.The change of score in quality of life of management group was also better than that of the control group. Conclusion Community health management can improve blood pressure control and the quality of life for elderly hypertensive patients.