摘要:
系统综述作为循证医学的核心方法,可向全面总结同一研究问题的所有证据,有助于临床医生、科研工作者和医疗卫生决策者在有限的时间里快速获取综合、精确、可靠的信息,使他们紧跟医学领域快速发展的步伐,拉近研究证据和医学实践的距离。然而,近年来人们对系统综述的质疑和批判不断。基于此,本文简要介绍了系统综述的起源和概念,详细阐述了系统综述的优势和局限性。最后,基于综述的应用和现状,对系统综述的未来作了展望。即使系统综述的方法学本身存在局限性,但仍是综合某一领域所有研究证据最权威的方法,因为我们目前没有更好的方法。如果系统地综合了所有研究的结果都是不可靠的,我们也没有理由说明其中的某个或某几个研究的结果就是公正无偏的。
Abstract:
As the core method of evidence-based medicine, systematic review comprehensively summarizes all the evidence of a particular problem. It enables clinicians, scientific researchers, and health policy makers to quickly obtain a great deal of comprehensive, accurate, and reliable information in a short time, and are crucial tools for them to keep up with rapidly evolving areas of medicine. Adequate systematic reviews integrate the evidence that is accumulating in a particular field to narrate the distance between research evidence and medical practice. However, in recent years, people are always questioning and criticizing systematic review. In this situation, we introduce the origin and concept of the system review briefly and elaborate the strengths and limitations of the system review in detail. Finally, on the basis of application and current situation of the systematic review, we describe the prospect of the systematic review. Even though the methodology of the systematic review has some limitations, it is still the most authoritative method for synthesizing all research evidence in a given field, because we have no better way. If the results of a systematic review of all studies are unreliable, there is no reason to say that the results of one or several of them are impartial or unbiased.