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产前抑郁与产后抑郁症的相关性

陈璐,  胡金萍,  拓明花,  张研婷,  牛建梅,  尚玉秀

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文章导航 > 中华疾病控制杂志  > 2020 >  24(3): 330-334
陈璐, 胡金萍, 拓明花, 张研婷, 牛建梅, 尚玉秀. 产前抑郁与产后抑郁症的相关性[J]. 中华疾病控制杂志, 2020, 24(3): 330-334. doi: 10.16462/j.cnki.zhjbkz.2020.03.016
引用本文: 陈璐, 胡金萍, 拓明花, 张研婷, 牛建梅, 尚玉秀. 产前抑郁与产后抑郁症的相关性[J]. 中华疾病控制杂志, 2020, 24(3): 330-334. doi: 10.16462/j.cnki.zhjbkz.2020.03.016
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CHEN Lu, HU Jin-ping, TUO Ming-hua, ZHANG Yan-ting, NIU Jian-mei, SHANG Yu-xiu. Correlation between prenatal depression and postpartum depression[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(3): 330-334. doi: 10.16462/j.cnki.zhjbkz.2020.03.016
Citation: CHEN Lu, HU Jin-ping, TUO Ming-hua, ZHANG Yan-ting, NIU Jian-mei, SHANG Yu-xiu. Correlation between prenatal depression and postpartum depression[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(3): 330-334. doi: 10.16462/j.cnki.zhjbkz.2020.03.016
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产前抑郁与产后抑郁症的相关性

doi: 10.16462/j.cnki.zhjbkz.2020.03.016
  • 1.

    750004 银川, 宁夏医科大学公共卫生与管理学院流行病与卫生统计学系

  • 2.

    750001 银川, 宁夏银川市妇幼保健院妇产科

  • 3.

    750001 银川, 宁夏中卫市中医院妇产科

  • 4.

    751700 中卫, 宁夏银川市妇幼保健院医院感染管理科

  • 5.

    750001 银川, 宁夏回族自治区人民医院健康管理中心临床营养科

基金项目: 宁夏自然科学基金资助项目(2019AAC03087);宁夏高等学校一流学科建设(公共卫生与预防医学学科)资助项目(NXYLXK2017B08)
详细信息
    通讯作者:

    尚玉秀, E-mail:shangyx1018@163.com

  • 中图分类号: R794.4

Correlation between prenatal depression and postpartum depression

  • 1.

    Department of Epidemiology and Health Statistics, School of Public Health and Management, NingXia Medical University, YinChuan 750004, China

  • 2.

    Department of Gynecology and Obstetrics, the Maternal and Child Health Hospital of Ningxia City, YinChuan 750001, China

  • 3.

    Hospital Infection Management Division, the Maternal and Child Health Hospital of Ningxia City, YinChuan 750001, China

  • 4.

    Department of Gynecology and Obstetrics, the Traditional Chinese Medicine Hospital of Zhongwei City in Ningxia, Zhongwei 751700, China

  • 5.

    Department of Health Management Center Clinical Nutrition, Region People's Hospital, Ningxia Hui Autonomous, Yinchuan 750001, China

Funds: Ningxia Natural Science Fund Project(2019AAC03087); First-class Discipline Construction(Public Health and Preventive Medicine)of Ningxia Higher Education School Funded Project(NXYLXK2017B08)
More Information

    摘要
  • 摘要:   目的   探讨产前抑郁与产后抑郁症的关系。   方法   选择银川市妇幼保健院与中卫市中医院2所医院的200名住院待产妇, 采用抑郁自评量表(self rating depression scale, SDS)与爱丁堡产后抑郁量表(Edinburgh postnatal depression scale, EPDS)分别调查产前与产后抑郁状况。   结果   200名产妇产前抑郁检出率为20.0%, 产后3 d抑郁检出率为26.0%, 产后42 d检出率为15.5%。有产前抑郁的产妇产后3 d(χ2=9.381, P=0.002)、产后42 d(χ2=11.923, P=0.001)抑郁检出率高于无产前抑郁者。Pearson相关分析显示, 产前SDS得分与产后3 d的EPDS得分、与产后42 d的EPDS得分均呈正相关(均有P < 0.05)。广义估计方程分析亦得出产前抑郁与产后3 d抑郁、产后42 d抑郁均呈正相关(均有P < 0.05)。多因素Logistic回归分析模型显示产前抑郁是产后3 d抑郁(OR=2.678, 95% CI:1.241~5.781, P=0.012)、产后42 d抑郁(OR=3.180, 95% CI:1.303~7.763, P=0.011)的危险因素。   结论   产前抑郁与产后抑郁症呈正相关, 产前抑郁增加了产后抑郁症的危险性。
    Abstract:   Objective   To explore the relationship between prenatal depression and postpartum depression.   Methods   Self rating depression scale(SDS) and Edinburgh postnatal depression scale(EPDS) was used to investigated the prenatal and postpartum depression status in 200 pregnant women from the Yinchuan maternal and child health hospital and the Zhongwei traditional chinese medicine hospital.   Results   The prevalence rate of prenatal depression in 200 women was 20.0%, the prevalence rate of 3 days postpartum depression was 26.0%, and the prevalence rate of 42 days postpartum depression was 15.5%. The prevalence rate of 3 days postpartum depression with prenatal depression in female were higher than that in female without prenatal depression(χ2=9.381, P=0.002). So were female that 42 days postpartum depression with prenatal depression(χ2 =11.923, P=0.001). The difference was statistically significant. Pearson correlation analysis showed that SDS score was positively correlated with EPDS score at 3 days postpartum and 42 days postpartum(all P < 0.05). Generalized estimating equation analysis also showed that prenatal depression was positively correlated with depression at 3 days postpartum and 42 days postpartum(all P < 0.05). Multivariate logistic regression analysis showed that prenatal depression was a risk factor for depression at 3 days postpartum(OR=2.678, 95% CI:1.241-5.781, P=0.012) and 42 days postpartum depression(OR =3.180, 95% CI:1.303-7.763, P=0.011).   Conclusion   Prenatal depression is positively associated with postpartum depression, and prenatal depression increases the risk of postpartum depression.
    • HTML全文

  • 表  1  产前抑郁与产后抑郁检出率比较

    Table  1.   Comparison of the detection rate of prenatal depression and postpartum depression

    变量 产前 产后3 d 产后42 d
    抑郁人数(%) χ2值 P值 抑郁人数(%) χ2值 P值 抑郁人数(%) χ2值 P值
    年龄(岁) 0.000 1.000 0.693 0.405 1.659 0.198
    ≤30 20.0(25/125) 28.0(35/125) 18.0(22/122)
    > 30 20.0(15/75) 22.7(17/75) 11.1(8/72)
    居住地 13.904 < 0.001 4.863 0.027 0.140 0.708
    城市 16.3(29/178) 23.6(42/178) 15.1(26/172)
    农村 50.0(11/22) 45.5(10/22) 18.2(4/22)
    文化程度 8.161 0.043 4.657 0.199 0.669 0.880
    初中及以下 34.2(13/38) 31.6(12/38) 18.9(7/37)
    高中 23.7(9/38) 44.7(17/38) 16.2(6/37)
    大专 17.9(10/56) 28.6(16/56) 12.7(7/55)
    大学及以上 11.8(8/68) 25.0(17/68) 15.4(10/65)
    夫妻关系 - 0.243 - 0.076 - 1.000
    较好 19.9(38/191) 24.6(47/191) 15.6(29/186)
    一般 12.5(1/8) 50.0(4/8) 14.3(1/7)
    较差 100.0(1/1) 100.0(1/1) 0.0(0/1)
    婆媳关系 - 0.353 - 0.023 - 0.014
    较好 19.7(35/178) 23.6(42/178) 13.9(24/173)
    一般 16.7(3/18) 38.9(7/18) 17.6(3/17)
    较差 50.0(2/4) 75.0(3/4) 75.0(3/4)
    睡眠质量 14.170 0.001 0.781 0.667 8.242 0.016
    较好 12.1(4/33) 27.3(9/33) 3.0(1/33)
    一般 13.6(15/110) 23.6(26/110) 14.2(15/106)
    较差 36.8(21/57) 19.3(11/57) 27.3(14/55)
    负性生活事件 24.663 < 0.001 1.976 0.160 2.089 0.148
    有 55.6(15/27) 37.0(10/27) 26.9(7/26)
    无 14.5(25/173) 24.3(42/173) 13.7(23/168)
    合计 20.0(40/200) 26.0(52/200) 15.5(30/194)
    注:“-”为Fisher确切法计算。
    下载: 导出CSV

    表  2  产前抑郁与产后抑郁的关系比较

    Table  2.   Comparison of prenatal depression andpostpartum depression

    产前抑郁 产后3 d 产后42 d
    抑郁人数(%) χ2值 P值 抑郁人数(%) χ2值 P值
    有 18(45.0) 9.381 0.002 13(33.3) 11.923 0.001
    无 34(21.3) 17(11.0)
    下载: 导出CSV

    表  3  产后3 d抑郁的多因素Logistic回归分析模型

    Table  3.   Multivariate logistic regression analysis of depression in postpartum 3 days

    变量 β值 Sx Wald值 OR(95% CI)值 P值
    产前抑郁 0.985 0.393 6.298 2.678(1.241~5.781) 0.012
    居住地 0.586 0.503 1.356 1.797(0.670~4.817) 0.244
    婆媳关系 0.867 0.402 4.650 2.381(1.082~5.238) 0.031
    常量 -2.939 0.731 16.151 0.053 < 0.001
    下载: 导出CSV

    表  4  产后42 d抑郁的多因素Logistic回归分析模型

    Table  4.   Multivariate logistic regression analysis of depression in postpartum 42 days

    变量 β值 Sx Wald值 OR(95% CI)值 P值
    产前抑郁 1.157 0.455 6.459 3.180(1.303~7.763) 0.011
    婆媳关系 0.778 0.437 3.165 2.177(0.924~5.129) 0.075
    睡眠质量 0.605 0.345 3.084 1.832(0.932~3.601) 0.079
    常量 -4.292 0.894 23.072 0.014 < 0.001
    下载: 导出CSV
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