兰州市2010—2019年丙型肝炎流行特征

马晶; 王梅; 谯小伟; 曹文珮; 李娟生; 任晓卫; 王宇红; 刘小宁

doi:10.16462/j.cnki.zhjbkz.2020.09.019

兰州市2010—2019年丙型肝炎流行特征

doi: 10.16462/j.cnki.zhjbkz.2020.09.019

1.
730000 兰州, 兰州大学公共卫生学院流行病与卫生统计所
2.
730000 兰州, 甘肃省妇幼保健院
3.
730000兰州,兰州市疾病预防控制中心

基金项目:

兰州市人才创新创业项目 2018-RC-53

详细信息

通讯作者:
刘小宁, E-mail: liuxn@lzu.edu.cn

中图分类号: R512.63;R181
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- 被引次数: 0
出版历程
- 收稿日期: 2019-11-18
- 修回日期: 2020-03-03
- 刊出日期: 2020-09-10

Epidemic characteristics of hepatitis C in Lanzhou City from 2010 to 2019

1.
Department of Epidemiology and Biostatistics, School of Public Health, Lanzhou University, Lanzhou 730000, China
2.
Gansu Provincial Maternity and Child-care Hospital, Lanzhou 730000, China
3.
Lanzhou Center for Disease Prevention and Control,Lanzhou 730000, China

Funds:

Talent innovation and Entrepreneurship Project of Lanzhou 2018-RC-53

More Information

Corresponding author: LIU Xiao-ning, E-mail: liuxn@lzu.edu.cn

摘要

摘要: 目的分析兰州市丙型肝炎（hepatitis C，HCV）流行特征及其变化趋势，为HCV防控措施的制定提供科学依据。方法收集2010-2019年兰州市HCV报告病例资料，采用Excel 2016、SPSS 21.0软件进行资料整理与统计，采用Joinpoint 4.7.0.0软件进行HCV年报告发病率趋势分析。结果 2010-2019年兰州市累计报告HCV病例22 697例，年均报告发病率为70.20/10万，Joinpoint回归模型结果显示，2010-2019年兰州市HCV年报告发病率整体呈平缓下降趋势，年度变化百分比（annual percent change，APC）为-7.49%（95%CI：-9.5%~-5.4%）。全年均有发病，无季节性增多；年均报告发病率排在前三的县（区）是城关区（59.79/10万）、七里河区（59.04/10万）和安宁区（43.46/10万）。报告病例男女性别比为1.06：1，病例主要集中在35~79岁之间，且发病率随着年龄的增加而逐渐上升，职业主要以农民和离退人员为主。结论兰州市HCV病例报告例数及年报告发病率整体呈下降趋势。应加强重点人群及地区疫情检测，继续规范病例诊断与报告制度。
- 丙型肝炎 /
- 流行病学 /
- 兰州市
Abstract: Objective To analyze the epidemiological characteristics and trend of hepatitis C in Lanzhou City, so as to provide scientific evidence for the strategy of prevention and control. Methods Data of hepatitis C virus infection reported cases in Lanzhou City from 2010 to 2019 were collected and analyzed by Excel 2016, SPSS 21.0 and Joinpoint 4.7.0.0 software. Results 22 697 cases of hepatitis C were reported in Lanzhou city from 2010 to 2019, the annual average incidence rate was 70.20/100 000. The results of Joinpoint regression models showed that the incidence of rates hepatitis C in Lanzhou City were decreased at an average annual percent changes (APC) of 7.49% (95% CI:-9.5% to -5.4%).The time distribution of onset was steady without seasonality. The three district with the highest reported incidence rates were Chengguan District (59.79/100 000), Qilihe District (59.04/100 000) and Anning District (43.36/100 000). The reported gender ratio was 1.06:1. The ages of onset were mainly from 35 to 79 years old, and the incidence of hepatitis C increased gradually with age. The occupational composition was mainly for farmers and retirees. Conclusions The number of reported cases and annual reported incidence of hepatitis C in Lanzhou show decreasing trends. It is necessary to strengthen the surveillance of key populations and areas, standardize the case report, and raise public awareness of hepatitis C virus infection.
- Hepatitis C /
- Epidemiologic characteristic /
- Lanzhou City

HTML全文

图 1 2010—2019年兰州市HCV年报告发病率趋势变化

Figure 1. Trend of annual reported incidence of hepatitis C in Lanzhou from 2010 to 2019

下载: 全尺寸图片幻灯片

图 2 2010—2019年HCV报告病例的时间分布

Figure 2. Temporal distribution of hepatitis C reported cases in Lanzhou from 2010 to 2019

下载: 全尺寸图片幻灯片

图 3 2010—2019年兰州市HCV报告病例的年龄和性别分布

Figure 3. Age and sex distribution of reported cases of hepatitis C in Lanzhou from 2010 to 2019

下载: 全尺寸图片幻灯片

表 1 2010—2019年兰州市HCV报告发病率情况

Table 1. Incidence of hepatitis C in Lanzhou from 2010 to 2019

年份(年)	人口数(万人)	病例数(例)	发病率(/10万)	标化发病率(/10万)
2010	323.59	2 793	86.31	80.18
2011	323.54	3 037	93.87	79.42
2012	323.30	3 139	97.09	81.78
2013	321.52	2 429	75.55	62.07
2014	321.43	2 052	63.84	50.48
2015	321.64	2 087	64.89	52.88
2016	321.90	2 031	63.09	50.47
2017	324.23	1 938	59.77	47.44
2018	325.55	1 707	52.43	41.29
2019	328.47	1 484	45.18	35.52

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表 2 2010—2019年兰州市HCV报告病例的职业分布

Table 2. The number of hepatitis C cases of different career in Lanzhou from 2010 to 2019

职业	累计报告例数(例)	构成比(%)
农民	6 277	27.66
离退人员	5 419	23.88
家务及待业	4 022	17.72
工人	1 876	8.27
干部职员	1 268	5.59
不详	1 034	4.56
其他	1 005	4.43
商业服务	726	3.20
教师	344	1.52
学生	244	1.08
医务人员	144	0.63
散居儿童	106	0.47
民工	80	0.35
餐饮食品业	52	0.23
牧民	50	0.22
公共场所服务员	25	0.11
海员及长途驾驶员	11	0.05
幼托儿童	9	0.04
保育员及保姆	5	0.02

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