The relationship between body mass index and lipid profile among hypertensive populations in Chinese rural districts

YANG Wen-bin; YU Tao; WANG Wen; WANG Li-wei; WANG Bin-yan; TANG Gen-fu; ZANG Tong-hua; QIN Xian-hui; WANG Yu; LI Jian-ping; HUO Yong; XU Xi-ping

doi:10.16462/j.cnki.zhjbkz.2016.05.007

Volume 20 Issue 5

May 2016

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2016 > 20(5): 456-459,473

YANG Wen-bin, YU Tao, WANG Wen, WANG Li-wei, WANG Bin-yan, TANG Gen-fu, ZANG Tong-hua, QIN Xian-hui, WANG Yu, LI Jian-ping, HUO Yong, XU Xi-ping. The relationship between body mass index and lipid profile among hypertensive populations in Chinese rural districts[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(5): 456-459,473. doi: 10.16462/j.cnki.zhjbkz.2016.05.007

Citation:

YANG Wen-bin, YU Tao, WANG Wen, WANG Li-wei, WANG Bin-yan, TANG Gen-fu, ZANG Tong-hua, QIN Xian-hui, WANG Yu, LI Jian-ping, HUO Yong, XU Xi-ping. The relationship between body mass index and lipid profile among hypertensive populations in Chinese rural districts[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(5): 456-459,473. doi: 10.16462/j.cnki.zhjbkz.2016.05.007

Citation:

YANG Wen-bin, YU Tao, WANG Wen, WANG Li-wei, WANG Bin-yan, TANG Gen-fu, ZANG Tong-hua, QIN Xian-hui, WANG Yu, LI Jian-ping, HUO Yong, XU Xi-ping. The relationship between body mass index and lipid profile among hypertensive populations in Chinese rural districts[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(5): 456-459,473. doi: 10.16462/j.cnki.zhjbkz.2016.05.007

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The relationship between body mass index and lipid profile among hypertensive populations in Chinese rural districts

doi: 10.16462/j.cnki.zhjbkz.2016.05.007

1. Institute of Biomedicine, Anhui Medical University, Hefei 230032, China;
2. National Clinical Research Center for Kidney Disease, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;
3. Department of Cardiology, Peking University First Hospital, Beijing 100034, China

Received Date: 2015-12-21
Rev Recd Date: 2016-01-28

Abstract

Abstract

Objective The purpose of the study was to investigate the relationship between body mass index (BMI) and lipid profile among hypertensive populations in Chinese rural districts. Methods An epidemiological investigation was conducted from May 2008 to July 2009 in rural districts of Anqing and Lianyungang. Height, weight, total cholesterol(TC), triglyceride(TG) and high-density lipoprotein cholesterol(HDL-C) were measured at baseline. Low-density lipoprotein cholesterol(LDL-C) was calculated using Friedewald formula. Multiple linear regression model was applied to evaluate the association between BMI and lipid profile. Results A total of 19 347 participants were included in the final analysis. The prevalence of overweight and obesity were 38.6% and 18.7%, respectively. Compared with normal weight participants, overweight and obese population had increased TC(β=3.00,P<0.001), TG(β=42.23,P<0.001) and LDL-C(β=3.69,P<0.001) levels, while HDL-C(β=-9.06,P<0.001) levels was significantly decreased. Furthermore, a stronger correlation between BMI and TG, LDL-C, HDL-C was observed in males(TG:β_male=51.02 vs β_female=37.67,P for interaction<0.001; LDL-C:β_male=3.88 vs β_female=3.14,P for interaction=0.016; HDL-C:β_male=-12.37 vs β_female=-7.27,P for interaction <0.001), smokers(TG:β_current=52.01 vs β_never=39.96,P for interaction <0.001; LDL-C:β_current=6.44 vs β_never=2.86,P for interaction =0.018; HDL-C:β_current=-12.53 vs β_never=-7.95,P for interaction <0.001) and drinkers(TG:β_current=50.57 vs β_never=39.99,P for interaction <0.001; LDL-C:β_current=8.15 vs β_never=2.46,P for interaction <0.001; HDL-C:β_current=-13.02 vs β_never=-7.74,P for interaction <0.001). However, there was no significant correlation between BMI and TC (sex:P for interaction=0.499,smoking:P for interaction=0.142,drinking:P for interaction=0.056)in any of these stratification.Conclusions Overweight and obesity is closely related to lipid levels,and stronger relationship between BMI and TG, LDL-C, HDL-C is observed in males, smokers and drinkers.
- Abnormal blood lipid,
- Overweight,
- Hypertension

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References(18)

References

中华人民共和国卫生部,中华人民共和国科学技术部,中华人民共和国国家统计局. 中国居民营养与健康现状 [J]. 中国心血管病研究杂志, 2004,2(12):919-922.

中国成人血脂异常防治指南制订联合委员会. 中国成人血脂异常防治指南 [J]. 中华心血管病杂志, 2007,35(5):390-419.

Meschia JF, Bushnell C, Boden-Albala B, et al. Guidelines for the primary prevention of stroke:a statement for healthcare professionals from the American Heart Association/American Stroke Association [J]. Stroke, 2014,45(12):1545-1588.

李莹,陈志红,周北凡,等. 血脂和脂蛋白水平对我国中年人群缺血性心血管病事件的预测作用 [J]. 中华心血管病杂志, 2004,32(7):643-647.

Lim SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 [J]. Lancet, 2012,380(9859):2224-2260.

中国高血压防治指南修订委员会. 中国高血压防治指南2010 [J]. 中华心血管病杂志, 2011,39(7):579-616.

陈伟伟,高润霖,刘力生,等. 《中国心血管病报告2014》概要 [J]. 中国循环杂志, 2015,30(7):617-622.

Williams PT. Changes in body weight and waist circumference affect incident hypercholesterolemia during 7 years of follow-up[J]. Obesity (Silver Spring), 2008,16(9):2163-2168.

Ishizaka N, Ishizaka Y, Toda E, et al. Impact of changes in waist circumference and BMI over one-year period on serum lipid data in Japanese individuals [J]. J Atheroscler Thromb, 2009,16(6):764-771.

Suka M, Yoshida K,Yamauchi K. Impact of body mass index on cholesterol levels of Japanese adults [J]. Int J Clin Pract, 2006,60(7):770-782.

周北凡. 我国成人体重指数和腰围对相关疾病危险因素异常的预测价值: 适宜体重指数和腰围切点的研究 [J]. 中华流行病学杂志, 2002,23 (1):5-10.

Barzi F, Woodward M, Czernichow S, et al. The discrimination of dyslipidaemia using anthropometric measures in ethnically diverse populations of the Asia–Pacific Region: the obesity in Asia Collaboration [J]. Obes Rev, 2010,11(2):127-136.

苏健,向全永,吕淑荣,等. 成年人体质指数、腰围与高血压、糖尿病和血脂异常的关系 [J]. 中华疾病控制杂志, 2015,19(7):696-700.

盛志峰,王平芳. 肥胖与胰岛素抵抗 [J]. 医学综述, 2003,9(7):428-431.

张岩,陈晓亭,宋惠珠,等. 肥胖所导致的胰岛素抵抗分子机制的研究进展 [J]. 检验医学, 2014,29(7):774-778.

Wietlisbach V, Marques-Vidal P, Kuulasmaa K, et al. The relation of body mass index and abdominal adiposity with dyslipidemia in 27 general populations of the WHO MONICA Project [J]. Nutr Metab Cardiovasc Dis, 2013,23(5):432-442.

Feng RN, Zhao C, Wang C, et al. BMI is strongly associated with hypertension, and waist circumference is strongly associated with type 2 diabetes and dyslipidemia, in Northern Chinese adults [J]. J Epidemiol, 2012,22(4):317-323.

Whitehead TP,Robinson D,Allaway SL. The effects of cigarette smoking and alcohol consumption on blood lipids: a dose-related study on men [J]. Ann Clin Biochem, 1996,33(Pt2):99-106.

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