The effect of hospital isolation in mid-stage dengue epidemic control

Objective To evaluate the effect of hospital isolation in mid-stage dengue epidemic control. Methods The interval between Oct 27 and Dec 14,2014 after the implement of hospital isolation was slected as the study period, the hospital isolation rate and reporting incidence rate were investigated, the average reporting community rate was selected as the effective indicators for multiple linear regression analysis. Results A total of 2 956 cases were reported with reporting incidence rate 23.02 per 100 000, 1 264(61.99%) cases were actually isolated in total 2 039 patients who should received isolation. Weekly average reporting cases was 422 with weekly average reporting incidence rate 3.29 per 100 000 and weekly average community rate 49.70%. With population density and average Breteau Index adjusted, along with hospital isolation rate increasing, the district reporting incidence rate(R²=0.613 8,P=0.045), weekly district average reporting incidence rate(R²=0.625 3,P=0.041), weekly district average reporting community rate(R²=0.634 1,P=0.037) was decreasing. With week, population density, and lag of 2 weeks for weekly average air temperature, weekly average rainfull and weekly average Breteau Index adjusted, and with the weekly district hospital isolation rate increasing, the weekly average reporting incidence rate (R²=0.520 4,P<0.001), and the average reporting community rate(R²=0.681 3,P<0.001)were decreasing. Conclusions Hospital isolation of cases in the period of communicability plays an important role in reducing the velocity of incidence and geographical diffusion, and should be aroused more attention in dengue control.