Serological survey of coxsackie virus A16 and enterovirus 71 infections among different population groups in Beijing

LI Jie; LIN Chang-ying; JIA Lei; YANG Yang; DU Yi-wei; LIANG Zhi-chao; LIU Yuan; CHEN Li-juan; WANG Quan-yi

doi:10.16462/j.cnki.zhjbkz.2016.08.004

Volume 20 Issue 8

Aug. 2016

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2016 > 20(8): 768-771,780

LI Jie, LIN Chang-ying, JIA Lei, YANG Yang, DU Yi-wei, LIANG Zhi-chao, LIU Yuan, CHEN Li-juan, WANG Quan-yi. Serological survey of coxsackie virus A16 and enterovirus 71 infections among different population groups in Beijing[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(8): 768-771,780. doi: 10.16462/j.cnki.zhjbkz.2016.08.004

Citation:

LI Jie, LIN Chang-ying, JIA Lei, YANG Yang, DU Yi-wei, LIANG Zhi-chao, LIU Yuan, CHEN Li-juan, WANG Quan-yi. Serological survey of coxsackie virus A16 and enterovirus 71 infections among different population groups in Beijing[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(8): 768-771,780. doi: 10.16462/j.cnki.zhjbkz.2016.08.004

Citation:

LI Jie, LIN Chang-ying, JIA Lei, YANG Yang, DU Yi-wei, LIANG Zhi-chao, LIU Yuan, CHEN Li-juan, WANG Quan-yi. Serological survey of coxsackie virus A16 and enterovirus 71 infections among different population groups in Beijing[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(8): 768-771,780. doi: 10.16462/j.cnki.zhjbkz.2016.08.004

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Serological survey of coxsackie virus A16 and enterovirus 71 infections among different population groups in Beijing

doi: 10.16462/j.cnki.zhjbkz.2016.08.004

Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China

Received Date: 2016-03-18
Rev Recd Date: 2016-05-01

Abstract

Abstract

Objective To understand the infection status of coxsackievirus A16 (CoxA16) and enterovirus 71 (EV71) among different population groups in Beijing. Methods A cluster random sampling was performed in nine districts of Beijing in 2012. Blood samples were collected and serological survey was conducted with enzyme-linked immunosorbent assay (ELISA) to detect levels of anti-EV71, anti-CoxA16 immunoglobulin G(IgG)and immunoglobulin M(IgM). Results A total of 2 140 people were enrolled in this study. The seropositive rates of anti-EV71 IgG and IgM were 27.0% and 1.6% respectively. The positive rates were 48.5% and 4.2% for anti-CoxA16 IgG and IgM, respectively. The positive rate of both anti-EV71 and CoxA16 IgM positive was 0.7%. The positive rate of both anti-EV71 and CoxA16 IgG positive was 17.2%. Significant difference of positive rate was observed among different age groups. The age group of 1-4 years old showed the highest positive rate for anti EV71 IgM. The age group of 5-9 years old showed the highest positive rate of anti-Cox16 IgM. The age group of 10-14 years old showed the highest positive rate of anti-EV71 IgG. The age group of 20-24 years old showed the highest positive rate of anti-CoxA16 IgG. The positive rate of anti-CoxA16 IgG was significantly higher in female compared with that in male. Conclusions Young children should be focused by the hand foot and mouth disease (HFMD) prevention and control, and geographical distribution factors should be considered during the development of HFMD prevention and control strategies.
- Hand,foot and mouth disease,
- Enterovirus infections,
- Coxsackievirus infections

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References(16)

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