Case-control study on association of carotid artery unstable carotid plaque, blood lipid and blood pressure with acute cerebral infarction

ZHANG Meng; ZHENG Hui; ZHANG Min; ZHOU Shan-shan; CHEN Qing

doi:10.16462/j.cnki.zhjbkz.2016.08.019

Volume 20 Issue 8

Aug. 2016

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ZHANG Meng, ZHENG Hui, ZHANG Min, ZHOU Shan-shan, CHEN Qing. Case-control study on association of carotid artery unstable carotid plaque, blood lipid and blood pressure with acute cerebral infarction[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(8): 831-834. doi: 10.16462/j.cnki.zhjbkz.2016.08.019

Citation:

ZHANG Meng, ZHENG Hui, ZHANG Min, ZHOU Shan-shan, CHEN Qing. Case-control study on association of carotid artery unstable carotid plaque, blood lipid and blood pressure with acute cerebral infarction[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(8): 831-834. doi: 10.16462/j.cnki.zhjbkz.2016.08.019

Citation:

ZHANG Meng, ZHENG Hui, ZHANG Min, ZHOU Shan-shan, CHEN Qing. Case-control study on association of carotid artery unstable carotid plaque, blood lipid and blood pressure with acute cerebral infarction[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(8): 831-834. doi: 10.16462/j.cnki.zhjbkz.2016.08.019

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Case-control study on association of carotid artery unstable carotid plaque, blood lipid and blood pressure with acute cerebral infarction

doi: 10.16462/j.cnki.zhjbkz.2016.08.019

1. Department of Ultrasound, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China;
2. Department of Clinical Laborator, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China;
3. Department of Neurology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China

Received Date: 2016-02-12
Rev Recd Date: 2016-05-08

Abstract

Abstract

Objective To investigate the relationship between carotid artery unstable plaque, blood lipid, blood pressure and the acute cerebral infarction. Methods Color doppler ultrasound was conducted to see the nature of carotid plaque. At the same time, the blood lipid and blood pressure levels of two groups were compared, case-control study design was used to compare the differences between the cerebral infarction group and the control group. Results Compared with the control group, the detection rate of carotid plaque in the cerebral infarction group was higher (χ²=12.477,P<0.001); and unstable plaques occupied 70.2% of the cerebral infarction group detected plaques(χ²=7.754,P=0.005), differences were statistically significant. TC,TG,VLDL and LDL-C of the cerebral infarction group was higher than that of the control group, and HDL-C was lower than that of the control group, differences were statistically significant (all P<0.05). As for the patients detected with unstable plaques, their HDL-C was lower than that of people without plaques and LDL-C was higher than those without plaques, differences were statistically significant(all P<0.05). Systolic blood pressure and diastolic blood pressure of the cerebral infarction group were both higher than that of the control group, differences were statistically significant(all P<0.05). Among the study objects with high blood pressure history, the systolic and diastolic pressure of the cerebral infarction group were higher than that of the control group(t₁=3.154,P₁=0.003;t₂=4.384,P₂<0.001) , differences were statistically significant. Conclusions The occurrence of acute cerebral infarct is related to carotid artery unstable carotid plaques, blood lipid and blood pressure. Positive prevention treatment in the early stage of risk factors has potential significance in reducing acute cerebral infarct occurrence rate.
- Cerebral infarction,
- Dyslipidemia,
- Blood pressure,
- Case control study

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