A case-control study of effectiveness of seasonal influenza vaccine in children in 2013-2014

HE Qing; XU Jian-xiong; WANG Ming; SHEN Ji-chuan; ZHANG Chun-huan; FU Chuan-xi

doi:10.16462/j.cnki.zhjbkz.2016.10.013

Volume 20 Issue 10

Oct. 2016

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2016 > 20(10): 1018-1021

HE Qing, XU Jian-xiong, WANG Ming, SHEN Ji-chuan, ZHANG Chun-huan, FU Chuan-xi. A case-control study of effectiveness of seasonal influenza vaccine in children in 2013-2014[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(10): 1018-1021. doi: 10.16462/j.cnki.zhjbkz.2016.10.013

Citation:

HE Qing, XU Jian-xiong, WANG Ming, SHEN Ji-chuan, ZHANG Chun-huan, FU Chuan-xi. A case-control study of effectiveness of seasonal influenza vaccine in children in 2013-2014[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(10): 1018-1021. doi: 10.16462/j.cnki.zhjbkz.2016.10.013

Citation:

HE Qing, XU Jian-xiong, WANG Ming, SHEN Ji-chuan, ZHANG Chun-huan, FU Chuan-xi. A case-control study of effectiveness of seasonal influenza vaccine in children in 2013-2014[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(10): 1018-1021. doi: 10.16462/j.cnki.zhjbkz.2016.10.013

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A case-control study of effectiveness of seasonal influenza vaccine in children in 2013-2014

doi: 10.16462/j.cnki.zhjbkz.2016.10.013

1. Department of Immunization Programme Planning, Center for Disease Control and Prevention of Guangzhou, Guangzhou 510440, China;
2. Department of Primary Public Health, Center for Disease Control and Prevention of Guangzhou, Guangzhou 510440, China

Received Date: 2016-04-27
Rev Recd Date: 2016-07-21

Abstract

Abstract

Objective To estimate the effectiveness of seasonal influenza vaccine in 2013-2014. Methods A category matching case-control study was conducted among children aged 6 to 59 months. The laboratory confirmed influenza cases were randomly selected from surveillance sites in Guangzhou during the study period. The healthy controls were randomly selected from children aged 6 to 59 months in the children's expanded programmed immunization administrative computerized system. Vaccine effectiveness (VE) was analyzed by unconditional Logistic regression. Results 2 690 subjects were collected in our study. We found that the VE for vaccination in 2013-2014 for children aged 6 to 59 months was 42.3%(95% CI:27.8%-53.8%). Full vaccination provided more protection than partial vaccination. Conclusions This post-licensing study of VE found moderate protection against influenza for vaccinated children aged 6 to 59 months. Annual and full vaccination should be encouraged in children.
- Influenza, human,
- Vaccines,
- Case-control studies

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References(19)

References

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