Carriage rate and antibiotic resistance of multidrug-resistant <i>S. aureus</i> isolates among residents in Guangdong Province

YU Hai-feng; WANG Xiao-lin; FAN Yan-ping; YAO Zhen-jiang; CHEN Si-dong; YE Xiao-hua

doi:10.16462/j.cnki.zhjbkz.2016.10.019

Volume 20 Issue 10

Oct. 2016

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2016 > 20(10): 1039-1042

YU Hai-feng, WANG Xiao-lin, FAN Yan-ping, YAO Zhen-jiang, CHEN Si-dong, YE Xiao-hua. Carriage rate and antibiotic resistance of multidrug-resistant S. aureus isolates among residents in Guangdong Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(10): 1039-1042. doi: 10.16462/j.cnki.zhjbkz.2016.10.019

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YU Hai-feng, WANG Xiao-lin, FAN Yan-ping, YAO Zhen-jiang, CHEN Si-dong, YE Xiao-hua. Carriage rate and antibiotic resistance of multidrug-resistant S. aureus isolates among residents in Guangdong Province[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2016, 20(10): 1039-1042. doi: 10.16462/j.cnki.zhjbkz.2016.10.019

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Carriage rate and antibiotic resistance of multidrug-resistant S. aureus isolates among residents in Guangdong Province

doi: 10.16462/j.cnki.zhjbkz.2016.10.019

1. Department of Occupation, Leliu Hospital of Shunde, Foshan 528322, China;
2. Department of Epidemiology and Health Statistics, School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510310, China

Received Date: 2016-05-25
Rev Recd Date: 2016-08-25

Abstract

Abstract

Objective To investigate the carriage rate and antibiotic resistance of multidrug-resistant S. aureus among animal-related workers and general population in Guangdong Province. Methods We surveyed the study population by face-to-face questionnaire and nasal swab sampling. All S. aureus isolates were tested for antibiotic susceptibility test, and the data were analyzed by chi-squared test. Results The carriage rates of S. aureus, multidrug-resistant S. aureus and methicillin-resistant S. aureus (MRSA) were higher in animal-related workers than in controls (13.3% vs 9.3%; 9.5% vs 3.4%; 7.0% vs 1.4%; all P<0.01). The rates of S. aureus isolates showed high levels of resistance to penicillin, clindamycin, tetracycline and erythromycin, and the dominant multidrug resistance pattern of multidrug-resistant S. aureus isolates were mainly resistant to clindamycin, erythromycin and tetracycline. S. aureus strains isolated from animal-related workers showed higher levels of resistances to antibiotics, except for penicillin, than those from general population. The antibiotic-resistant rate was higher in MRSA isolates than in methicillin-sensitive S. aureus isolates. Conclusions This study suggests that occupational animal contact may lead to the infection of drug resistant bacteria.
- Staphylococcus aureus,
- Occupational exposure,
- Epidemiologic methods

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