Study on influencial factors of adherence to anti-retroviral treatment among people who co-infected with HIV/HCV in Fuyang City, Anhui Province

Objective To investigate the adherence to anti-retroviral treatment and related factors among human immunodeficiency virus (HIV) and hepatitis C virus (HCV) co-infectors. Methods In this cross-sectional study, 256 HIV and HCV co-infectors were recruited by convenience sampling method, and information about demography, taking medicine and therapy were collected and analyzed. Results A total of 256 HIV/HCV co-infectors were investigated, 34.0% of them missed dose in the last month. Multiple Logistic regression analysis showed that HIV/HCV co-infectors with long marriage (OR=3.049, 95% CI:1.435-6.481, P=0.004), longer time of treatment with antiretroviral therapy (ART) (OR=1.803, 95% CI:1.251-2.599, P=0.002), frequent alcohol consumption (OR=2.512, 95% CI:1.152-5.478, P=0.021) were risk factors of missed dose, while female (OR=0.180, 95% CI:0.089-0.366, P<0.001) and co-infectors who take a reminder method (OR=0.315, 95% CI:0.159-0.626, P=0.001) were protective factors for missed dose. Conclusions The ART adherence rate of HIV/HCV co-infectors was lower in Anhui Province, comprehensive intervention measures should be taken to promote the ART adherence.