Association between fasting glucose and branchial-ankle pulse wave velocity among hypertensive population in rural areas of Eastern China

CAO Jing-jing; ZHANG Jing-ping; WANG Bin-yan; QIN Xian-hui; ZANG Tong-hua; XU Xi-ping

doi:10.16462/j.cnki.zhjbkz.2019.06.006

Volume 23 Issue 6

Jun. 2019

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Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2019 > 23(6): 646-649, 689

CAO Jing-jing, ZHANG Jing-ping, WANG Bin-yan, QIN Xian-hui, ZANG Tong-hua, XU Xi-ping. Association between fasting glucose and branchial-ankle pulse wave velocity among hypertensive population in rural areas of Eastern China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(6): 646-649, 689. doi: 10.16462/j.cnki.zhjbkz.2019.06.006

Citation:

CAO Jing-jing, ZHANG Jing-ping, WANG Bin-yan, QIN Xian-hui, ZANG Tong-hua, XU Xi-ping. Association between fasting glucose and branchial-ankle pulse wave velocity among hypertensive population in rural areas of Eastern China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(6): 646-649, 689. doi: 10.16462/j.cnki.zhjbkz.2019.06.006

Citation:

CAO Jing-jing, ZHANG Jing-ping, WANG Bin-yan, QIN Xian-hui, ZANG Tong-hua, XU Xi-ping. Association between fasting glucose and branchial-ankle pulse wave velocity among hypertensive population in rural areas of Eastern China[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2019, 23(6): 646-649, 689. doi: 10.16462/j.cnki.zhjbkz.2019.06.006

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Association between fasting glucose and branchial-ankle pulse wave velocity among hypertensive population in rural areas of Eastern China

doi: 10.16462/j.cnki.zhjbkz.2019.06.006

Institute of Biomedicine, Anhui Medical University, Hefei 230032, China

Funds:

National Natural Science Foundation of China 81473052

More Information

Corresponding author: XU Xi-ping, E-mail: xipingxu126@126.com
Received Date: 2018-11-16
Rev Recd Date: 2019-02-02
Publish Date: 2019-06-10

Abstract

Abstract

Objective To explore the relationship between fasting blood glucose and branchial-ankle pulse wave velocity (baPWV) levels among hypertensive population in rural areas of Eastern China. Methods A cross-sectional analysis were conducted among hypertensive population in Lianyungang and Anqing city from July to September 2013. Multivariable linear regression models were used to analyze the association of serum glucose and baPWV. Results A total of 3 894 hypertensive participants were included in the present study. The prevalence of normal fasting glucose (NFG), impaired fasting glucose (IFG) and diagnosed diabetes (DM) were 44.5%, 43.0%, and 12.5%, respectively. Each 1-mmol/L increase in fasting blood glucose levels was significantly associated with a 26.2 cm/s increase in baPWV levels (95% CI: 19.6-32.8, P < 0.001). Consistently, significantly higher baPWV levels were observed in participants with IFG (β=50.4 cm/s, 95% CI: 28.4-72.3, P < 0.001) and DM (β=113.4 cm/s, 95% CI: 80.2-146.5, P < 0.001) when compared to those with NFG. Furthermore, a stronger positive association between fasting blood glucose and baPWV was observed in participants with systolic blood pressure (SBP) ≥ 140 mmHg (β=34.3 cm/s, 95% CI: 24.5-44.2, P < 0.001; vs. < 140 mmHg; β=18.1 cm/s, 95% CI: 9.1-27.2, P < 0.001; P_interaction=0.027). Conclusion There was a positive association between fasting blood glucose and baPWV levels among hypertensive population in rural areas of Eastern China.
- Serum glucose,
- pulse wave velocity,
- arterial stiffness

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References(20)

References

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