Epidemiological characteristics and temporal-spatial clustering analysis of hand, foot and mouth disease in Shantou City

ZHANG Chi; ZHANG Xu-bin; YAO Li-jun; XU Lu; XU Guang-xing; ZHANG Zhi-hua; JIANG Su-hong; XIE Run-sheng; LI Li-ping

doi:10.16462/j.cnki.zhjbkz.2020.05.015

Volume 24 Issue 5

Jul. 2020

Turn off MathJax

Article Contents

Article Navigation > CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION > 2020 > 24(5): 573-578

ZHANG Chi, ZHANG Xu-bin, YAO Li-jun, XU Lu, XU Guang-xing, ZHANG Zhi-hua, JIANG Su-hong, XIE Run-sheng, LI Li-ping. Epidemiological characteristics and temporal-spatial clustering analysis of hand, foot and mouth disease in Shantou City[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(5): 573-578. doi: 10.16462/j.cnki.zhjbkz.2020.05.015

Citation:

ZHANG Chi, ZHANG Xu-bin, YAO Li-jun, XU Lu, XU Guang-xing, ZHANG Zhi-hua, JIANG Su-hong, XIE Run-sheng, LI Li-ping. Epidemiological characteristics and temporal-spatial clustering analysis of hand, foot and mouth disease in Shantou City[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(5): 573-578. doi: 10.16462/j.cnki.zhjbkz.2020.05.015

Citation:

ZHANG Chi, ZHANG Xu-bin, YAO Li-jun, XU Lu, XU Guang-xing, ZHANG Zhi-hua, JIANG Su-hong, XIE Run-sheng, LI Li-ping. Epidemiological characteristics and temporal-spatial clustering analysis of hand, foot and mouth disease in Shantou City[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2020, 24(5): 573-578. doi: 10.16462/j.cnki.zhjbkz.2020.05.015

PDF( 9629 KB)

Epidemiological characteristics and temporal-spatial clustering analysis of hand, foot and mouth disease in Shantou City

doi: 10.16462/j.cnki.zhjbkz.2020.05.015

1.
Center for Disease Control and Prevention of Shantou, Shantou 515000, China
2.
Guangdong Provincial Hospital of Chinese Medicine 510000, China
3.
Medical College of Shantou University 515000, China

Funds: Science and Technology Planning Project of Guangdong Province(2016A020216026)

More Information

Corresponding author: LI Li-ping, E-mail:lpli@stu.edu.cn
Received Date: 2019-10-21
Rev Recd Date: 2020-01-20
Publish Date: 2020-05-10

Abstract

Abstract

Objective To explore the epidemiological characteristics and temporal-spatial clustering of hand, foot and mouth disease(HFMD) from 2009 to 2018 in Shantou City, as a means of providing a scientific basis for conducting effective control strategies. Methods The epidemic data of HFMD from 2009 to 2018 was collected. Spatial autocorrelation analysis and spatiotemporal scan statistics were used to analyse the clustering of HFMD in time and space. Results A total of 77 814 cases of HFMD were reported in Shantou City from 2009 to 2018. The annual average incidence was 143.52/100 000. Children under three years old comprised the HFMD high-risk population.The major HFMD-incidence peak period was from April to July, and the secondary incidence peak period was from September to November. Global and local spatial autocorrelation analysis demonstrated that positive spatial autocorrelation was observed at street(town) level. Twenty-five streets(towns) of Shantou City were hotspot areas, indicating the high incidence of HFMD. Two clustering was found by time-space scanning from 2009-2018, and the Class 1 clustering area(RR=3.56, LLR=9 444.26, P < 0.001) centred on Tongyi and Xinfu street, with a radius of 10.05 km, involving 25 streets(towns) of Shantou City. Conclusions A significant feature of spatiotemporal clustering was shown in the HFMD incidence in Shantou City from 2009 to 2018. Effective prevention and control measures should be undertaken for the high-risk population in high-prevalence area and season to decrease the incidence of HFMD in Shantou City.
- Hand,
- foot and mouth disease,
- Epidemiological characteristics

FullText(HTML)

References(17)

References

[1]	国家卫生健康委员会.手足口病诊疗指南(2018年版)[J].中国病毒病杂志, 2018, 8(5): 347-352.DOI: 10.16505/j.2095-0136.2018.0063. National Health Commission of the People's Republic of China. Guidelines for the diagnosis and treatment of hand foot and mouth disease(2018 version)[J]. Chin J Viral Dis, 2018, 8(5): 347-352. DOI: 10.16505/j.2095-0136.2018.0063.
[2]	Jones E, Pillay TD, Liu FF, et al. Outcomes following severe hand foot and mouth disease: a systematic review and meta-analysis[J]. Eur J Paediatr Neurol, 2018, 22(5): 763-773.DOI: 10.1016/j.ejpn.2018.04.007.
[3]	Zhang DG, Chen JL, Ba-Thein W. Hand-foot-mouth disease and use of steroid, intravenous immunoglobulin, and traditional Chinese herbs in a tertiary hospital in Shantou, China[J]. BMC Complement Altern Med, 2018, 18(1): 190.DOI: 10.1186/s12906-018-2259-9.
[4]	陈敏玫.手足口疾病原谱和基因多态性研究进展[J].应用预防医学, 2017, 23(1): 91-94.DOI: 10.3969/j.issn.1673-758X.2017.01.027. Chen MM. The research progress of the pathogenic spectrum and gene polymorphism of hand-foot-mouth disease[J]. J Applied Prev Med, 2017, 23(1): 91-94. DOI: 10.3969/j.issn.1673-758X.2017.01.027.
[5]	赵静, 傅超.经济特区发展战略研究-以汕头经济特区为例[J].中国物价, 2016, 6: 73-75. http://www.cnki.com.cn/Article/CJFDTotal-ZGWJ201606023.htm Zhao J, Fu C. The development strategy of special economic zones-the example of Shantou special economic zone[J]. China Price, 2016, 6: 73-75. http://www.cnki.com.cn/Article/CJFDTotal-ZGWJ201606023.htm
[6]	吴令杰, 张海生, 林沛鸿, 等. 2008-2012年汕头市1689例手足口病患儿流行病学特征分析[J].热带医学杂志, 2013, 13(10): 1274-1275. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=rdyxzz201310030 Wu LJ, Zhang HS, Lin PH, et al. Epidemiology and clinical characteristics of hand-foot-mouth disease in Shantou city from 2008 to 2012[J]. J Trop Med, 2013, 13(10): 1274-1275. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=rdyxzz201310030
[7]	蒋丽娜, 谭毅, 王晶, 等. 2008-2015年广西手足口病流行病学特征及时空聚集性分析[J].中华疾病控制杂志, 2017, 21(4): 340-344.DOI: 10.16462/j.cnki.zhjbkz.2017.04.005. Jiang LN, Tan Y, Wang J, et al. Epidemiological characteristics and temporal-spatial clustering of hand, foot and mouth disease in Guangxi from 2008 to 2015[J]. Chin J Dis Control Prev, 2017, 21(4): 340-344. DOI: 10.16462/j.cnki.zhjbkz.2017.04.005.
[8]	Xing WJ, Liao QH, Viboud C, et al. Epidemiological characteristics of hand-foot-and-mouth disease in China, 2008-2012[J]. Lancet Infect Dis, 2014, 14(4): 308-318.DOI: 10.1016/S1473-3099(13)70342-6.
[9]	Brein A, Sherrard-Smith E, Sile B, et al. Spatical clusters of gonorrhea in England with particular reference to the outcome of partner notification: 2012 and 2013[J]. PLoS One, 2018, 13(4): e0195178.DOI: 10.1371/journal.pone.0195178.eCollection 2018.
[10]	Zhu B, Liu J, Fu Y, et al. Spatio-temporal epidemiology of viral hepatitis in China(2003-2015): implications for prevention and control policies[J]. Int J Environ Res Public Health, 2018, 15(4): 661.DOI: 10.3390/ijerph15040661.
[11]	高阔, 甘筱青.我国患者双向转诊行为决策及影响因素研究[J].中国全科医学, 2015, 18(28): 3393-3395.DOI: 10.3969/j.issn.1007-9572.2015.28.003. Gao K, Gan XQ. Behavioral decision in two-way referral and its influencing factors in China[J]. Chin Gen Pract, 2015, 18(28): 3393-3395. DOI: 10.3969/j.issn.1007-9572.2015.28.003.
[12]	鲍婷, 王佑娟, 马原林, 等.居民就医行为研究进展[J].中国社会医学杂志, 2019, 36(2): 135-138.DOI: 10.3969/j.issn.1673-5625.2019.02.007. Bao T, Wang YJ, Ma YL, et al. Research progress of health care seeking behavior among residents[J]. Chin J Soc Medi, 2019, 36(2): 135-138. DOI: 10.3969/j.issn.1673-5625.2019.02.007.
[13]	Kulldorff M, Heffeman R, Hartman J, et al. A space-time permutation scan statistic for disease outbreak detection[J]. PLoS Med, 2005, 2(3): e59.DOI: 10.1371/journal.pmed.0020059.
[14]	蒋丽娜, 谭毅, 王晶, 等. 2008-2015年广西手足口病流行病学特征及时空聚集性分析[J].中华疾病控制杂志, 2017, 21(4): 340-344.DOI: 10.16462/j.Cnki.Zhjbkz.2017.04.005. Jiang LN, Tan Y, Wang J, et al. Epidemiological characteristics and temporal-spatial clustering of hand, foot and mouth disease in Guangxi from2008 to 2015[J]. Chin J Dis Control Prev, 2017, 21(4): 340-344. DOI: 10.16462/j.Cnki.Zhjbkz.2017.04.005.
[15]	陈灿, 王虹玲, 张辉, 等. 2009-2016年浙江省舟山海岛地区手足口病时空聚集性及病原谱变化分析[J].疾病监测, 2018, 33(1): 45-49.DOI: 10.3784/j.issn.1003-9961.2018.01.011. Chen C, Wang HL, Zhang H, et al. Spatial-temporal clustering and pathogen spectrum change of hand, foot and mouth disease in Zhoushan islands, Zhejiang, 2009-2016[J]. Dis Surveillance, 2018, 33(1): 45-49. DOI: 10.3784/j.issn.1003-9961.2018.01.011.
[16]	胡跃华, 肖革新, 郭莹, 等. 2008-2011年中国大陆手足口病流行特征分析[J].中华疾病控制杂志, 2014, 18(8): 693-697. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=jbkzzz201408001 Hu YH, Xiao GX, Guo Y, et al. The epidemic features of the hand, foot, and mouth disease during 2008-2011 in China[J]. Chin J Dis Control Prev, 2014, 18(8): 693-697. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=jbkzzz201408001
[17]	李欣欣, 候文平, 米卓, 等. 2012-2015年北京市大兴区手足口病时空聚集性分析[J].国际病毒学杂志, 2016, 23(5): 311-317.DOI: 10.3760/cma.j.issn.1673-4092.2016.05.007. Li XX, Hou WP, Mi Z, et al. Temporal and spatial clustering characteristic of hand-foot-mouth disease in Daxing, 2012-2015[J]. Int J Virol, 2016, 23(5): 311-317. DOI: 10.3760/cma.j.issn.1673-4092.2016.05.007.