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CN 34-1304/RISSN 1674-3679

Volume 26 Issue 6
Jun.  2022
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REN Ning-jun, LI Yuan-sheng, ZHANG Wen-xin, WANG Ruo-lan, FAN Song, LI Ai-ling. Disease burden and trend of HIV/AIDs among the elderly in China during 1990-2019[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(6): 639-644. doi: 10.16462/j.cnki.zhjbkz.2022.06.004
Citation: REN Ning-jun, LI Yuan-sheng, ZHANG Wen-xin, WANG Ruo-lan, FAN Song, LI Ai-ling. Disease burden and trend of HIV/AIDs among the elderly in China during 1990-2019[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(6): 639-644. doi: 10.16462/j.cnki.zhjbkz.2022.06.004

Disease burden and trend of HIV/AIDs among the elderly in China during 1990-2019

doi: 10.16462/j.cnki.zhjbkz.2022.06.004
Funds:

Sichuan Sexual Sociology and Sexuality Education Research Center Project SXJYB2004

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  • Corresponding author: LI Ai-ling, E-mail: 306816481@qq.com
  • Received Date: 2021-10-14
  • Rev Recd Date: 2022-02-18
  • Available Online: 2022-06-16
  • Publish Date: 2022-06-10
  •   Objective  To describe and analyze the prevalence, morbidity rate, mortality rate, and disability-adjusted life years (DALYs) rate of HIV/AIDS among the elderly in China from 1990 to 2019.  Methods  Data was collected from the Global Burden of Disease Study 2019(GBD 2019). Statistical description was used to analyze disease burden indicators by age, gender, and year. Temporal trend analysis was conducted by Joinpoint regression models. Annual percentage change (APC) and average annual percentage change (AAPC) were calculated for prevalence, morbidity rate, mortality rate, and DALYs rate.  Results  From 1990 to 2019, the age-standardized prevalence of HIV/AIDS among the elderly in China increased from 7.56/105 to 48.90/105. The age-standardized morbidity rate increased from 1.03/105 to 1.89/105.The age-standardized mortality rate increased from 0.35/105 to 2.97/105. The DALYs rate increased from 11.01/105 to 90.51/105. According to the Joinpoint results, from 1990-2019, there was an overall increasing trend in the standardized prevalence, mortality rate, morbidity rate, DALYs rate of HIV/AIDS among the elderly in China, with AAPC of 6.71%, 1.91%, 7.65%, and 7.52% respectively. The differences were all statistically significant with P < 0.05.  Conclusions  The disease burden of HIV/AIDS among the elderly in China is still severe. The disease burden index is on the rise. Early HIV/AIDS screening and health education should be strengthened, and targeted preventive measures should be formulated according to the HIV/AIDS burden characteristics among the elderly.
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  • [1]
    韦辉, 李博, 蓝光华. 中国老年人群艾滋病流行特征研究进展[J]. 应用预防医学, 2021, 27(2): 189-193. doi: 10.3969/j.issn.1673-758X.2021.02.032

    Wei H, Li B, Lan GH. Advances in the study of HIV epidemic characteristics in the Chinese elderly population [J]. Applied Prev Med, 2021, 27(2): 189-193. doi: 10.3969/j.issn.1673-758X.2021.02.032
    [2]
    吴尊友. 我国实现艾滋病防治策略三个90%的进展与挑战[J]. 中华疾病控制杂志, 2016, 20(12): 1187-1189. DOI: 10.16462/j.cnki.zhjbkz.2016.12001.

    Wu ZY. The progress and challenges of promoting HIV/AIDS 90-90-90 strategies in China [J]. Chin J Dis Control Prev, 2016, 20(12): 1187-1189. DOI: 10.16462/j.cnki.zhjbkz.2016.12001.
    [3]
    Shiau S, Bender AA, O'Halloran JA, et al. The current state of HIV and aging: findings presented at the 10th international workshop on HIV and aging [J]. AIDS Res Hum Retroviruses, 2020, 36(12): 973-981. DOI: 10.1089/aid.2020.0128.
    [4]
    Sabin CA, Reiss P. Epidemiology of ageing with HIV: what can we learn from cohorts? [J]. Aids, 2017, 31(Suppl 2): S121-S128. DOI: 10.1097/qad.0000000000001374.
    [5]
    Jia Z, Ruan Y, Lu Z. HIV incidence and mortality in China [J]. Lancet, 2015, 385(9977): 1510. DOI: 10.1016/s0140-6736(15)60753-x.
    [6]
    Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the global burden of disease study 2017 [J]. Lancet, 2018, 392(10159): 1789-1858. DOI: 10.1016/s0140-6736(18)32279-7.
    [7]
    Adler WH, Baskar PV, Chrest FJ, et al. HIV infection and aging: mechanisms to explain the accelerated rate of progression in the older patient [J]. Mech Ageing Dev, 1997, 96(1-3): 137-155. DOI: 10.1016/s0047-6374(97)01888-5.
    [8]
    Bernard C, Balestre E, Coffie PA, et al. Aging with HIV: what effect on mortality and loss to follow-up in the course of antiretroviral therapy? The IeDEA West Africa Cohort Collaboration [J]. HIV/AIDS (Auckland, N.Z. ), 2018, 16(10): 239-252. DOI: 10.2147/HIV.S172198.
    [9]
    李辉章, 杜灵彬. Joinpoint回归模型在肿瘤流行病学时间趋势分析中的应用[J]. 中华预防医学杂志, 2020, 54(8): 908-912. DOI: 10.3760/cma.j.cn112150-20200616-00889.

    Li HZ, Du LB. Application of Joinpoint regression model in cancer epidemiological time trend analysis [J]. Chin J Prev Med, 2020, 54(8): 908-912. DOI: 10.3760/cma.j.cn112150-20200616-00889.
    [10]
    Kim HJ, Fay MP, Feuer EJ, et al. Permutation tests for joinpoint regression with applications to cancer rates [J]. Stat Med, 2000, 19(3): 335-351. DOI: 10.1002/(sici)1097-0258(20000215)19:3<335::aid-sim336>3.0.co;2-z.
    [11]
    郭剑, 高洪艳, 王媛. 1990-2017年中国艾滋病疾病负担分析[J]. 中国艾滋病性病, 2021, 27(4): 356-359. DOI: 10.13419/j.cnki.aids.2021.04.07.

    Gao J, Gao HY, Wang Y. Burden of HIV/AIDS disease in China from 1990 to 2017 [J]. Chin J AIDS STD, 2021, 27(4): 356-359. DOI: 10.13419/j.cnki.aids.2021.04.07.
    [12]
    张薇, 张艺, 申幸福, 等. 湖北省≥50岁艾滋病病毒感染者/艾滋病患者特征分析[J]. 江苏预防医学, 2018, 29(5): 497-499, 567. DOI: 10.13668/j.issn.1006-9070.2018.05.006.

    Zhang W, Zhang Y, Shen XF, et al. Epidemiologic chareacteristics of aged HIV/AIDS cases older than 50 years reported through internet based direct reporting system in Hubei province [J]. Jiangsu J of Prev Med, 2018, 29(5): 497-499, 567. DOI: 10.13668/j.issn.1006-9070.2018.05.006.
    [13]
    邱智, 刘保兴, 李宏军, 等. 北京地区老年男性性生活现状初步调查[J]. 中华男科学杂志, 2010, 16(3): 223-226. DOI: 10.13263/j.cnki.nja.2010.03.009.

    Qiu Z, Liu BX, Li HJ, et al. Sexual function of aging males in Beijing: A primary investigation [J]. National J of Andr, 2010, 16(3): 223-226. DOI: 10.13263/j.cnki.nja.2010.03.009.
    [14]
    Xie T, Wu N. Epidemiological and mortality analysis of older adults with HIV in eastern China [J]. Clin Interv Aging, 2013, 8: 1519-1525. DOI: 10.2147/cia.S53657.
    [15]
    Chen X, Li X, Qin B, et al. Older HIV-positive adults in Xiangxi, China: infection modes and associated risk factors [J]. Sex Transm Dis, 2012, 39(9): 716-719. DOI: 10.1097/OLQ.0b013e31825af361.
    [16]
    张秋月, 张彤. 艾滋病抗病毒治疗现状及其研究进展[J]. 中国病毒病杂志, 2018, 8(2): 103-108. DOI: 10.16505/j.2095-0136.2018.0020.

    Zhang QY, Zhang T. Research progress of AIDS anti-retro viral therapy [J]. Chin J Viral Dis, 2018, 8(2): 103-108. DOI: 10.16505/j.2095-0136.2018.0020.
    [17]
    Gao D, Zou Z, Zhang W, et al. Age-period-cohort analysis of HIV mortality in China: Data from the Global Burden of Disease Study 2016 [J]. Sci Rep, 2020, 10(1): 7065. DOI: 10.1038/s41598-020-63141-1.
    [18]
    Puhr R, Kumarasamy N, LY PS, et al. HIV and Aging: Demographic Change in the Asia-Pacific Region [J]. J Acquir Immune Defic Syndr, 2017, 74(5): e146-e148. DOI: 10.1097/qai.0000000000001258.
    [19]
    笪琴, 彭国平, 汤恒, 等. 湖北省2014-2016年艾滋病感染者/艾滋病患者晚发现情况分析[J]. 实用预防医学, 2019, 26(3): 268-270. DOI: 10.3969/j.issn.1006-3110.2019.03.004.

    Da Q, Peng GP, Tang H, et al. Late diagnosis phenmenna among HIV/AIDS patients in Hubei province, 2014-2016 [J]. Pract Prev Med, 2019, 26(3): 268-270. DOI: 10.3969/j.issn.1006-3110.2019.03.004.
    [20]
    王炜, 张幸, 郝晓刚. 衢州市2002-2016年老年HIV/AIDS病人流行病学特征分析[J]. 中国艾滋病性病, 2017, 23(12): 1105-1106, 1137. DOI: 10.13419/j.cnki.aids.2017.12.08.

    Wang W, Zhang X, Hao XG. HIV/AIDS epidemiological characteristis of the elderly in Quzhou city from 2002 to 2016 [J]. Chin J AIDS STD, 2017, 23(12): 1105-1106, 1137. DOI: 10.13419/j.cnki.aids.2017.12.08.
    [21]
    叶振淼, 王大勇, 赵丽娜, 等. 2012-2016年温州市50岁及以上艾滋病病毒感染者/艾滋病患者流行特征分析[J]. 现代预防医学, 2018, 45(5): 776-780. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF201805003.htm

    Ye ZM, Wang DY, Zhao LN, et al. Epidemiological characteristics of HIV/AIDS patients aged 50 and above in Wenzhou, 2012-2016 [J]. Mod Prev Med, 2018, 45(5): 776-780. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF201805003.htm
    [22]
    姜影, 张国磊, 梁欣, 等. 北京市石景山区艾滋病防治综合管理模式探讨[J]. 首都公共卫生, 2017, 11(2): 77-79. DOI: 10.16760/j.cnki.sdggws.2017.02.011.

    Jiang Y, Zhang GL, Liang X, et al. A discussion on comprehensive AIDS prevention and treatment patterns in Shijingshan district, Beijing [J]. Cap J of Public Health, 2017, 11(2): 77-79. DOI: 10.16760/j.cnki.sdggws.2017.02.011.
    [23]
    一苇. 我国对艾滋病人及感染者实行"四免一关怀" [J]. 中国健康教育, 2005, (1): 37. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGJK200501015.htm

    Yi W. China implements "four free and one care" for AIDS and infected people [J]. Chin J of Health Education, 2005, (1): 37. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGJK200501015.htm
    [24]
    张晗希, 韩孟杰, 周郁, 等. 应用中断时间序列分析我国"四免一关怀"政策实施前后对艾滋病相关病死率的影响[J]. 中华流行病学杂志, 2020, 41(3): 406-411. DOI: 10.3760/cma.j.issn.0254-6450.2020.03.024.

    Zhang HX, Han MJ, Zhou Y, et al. Interrupted time series analysis for influence on HIV related fatality of implementation of "Four Free Services One Care" policy in China [J]. Chin J Epidemiol, 2020, 41(3): 406-411. DOI: 10.3760/cma.j.issn.0254-6450.2020.03.024.
    [25]
    李佳, 赵燕, 晋灿瑞, 等. 艾滋病抗病毒治疗政策和策略分析与思考[J]. 中国艾滋病性病, 2013, 19(2): 144-147. DOI: 10.13419/j.cnki.aids.2013.02.018.

    Li J, Zhao Y, Jin CR, et al. Analysis of antiretroviral treatment policy and strategy for AIDS [J]. Chin J AIDS STD, 2013, 19(2): 144-147. DOI: 10.13419/j.cnki.aids.2013.02.018.
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