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CN 34-1304/RISSN 1674-3679

LU Tian-huan, YU Chuan-hua. Analysis on the status and trend of dementia burden in China based on the global perspective[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(6): 684-690. doi: 10.16462/j.cnki.zhjbkz.2022.06.012
Citation: LU Tian-huan, YU Chuan-hua. Analysis on the status and trend of dementia burden in China based on the global perspective[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2022, 26(6): 684-690. doi: 10.16462/j.cnki.zhjbkz.2022.06.012

Analysis on the status and trend of dementia burden in China based on the global perspective

doi: 10.16462/j.cnki.zhjbkz.2022.06.012
Funds:

National Natural Science Foundation of China 82173626

National Natural Science Foundation of China 81773552

National Key Research and Development Program of China 2018YFC1315302

More Information
  • Corresponding author: YU Chuan-hua, E-mail: yuchua@whu.edu.cn
  • Received Date: 2021-10-08
  • Rev Recd Date: 2022-01-25
  • Available Online: 2022-06-16
  • Publish Date: 2022-06-10
  •   Objective  Analyzing the disease burden and its changing trend of dementia in China from 1990 to 2019 to provide a scientific basis for the prevention and control of dementia.  Methods  Based on the Global Burden of Disease (GBD) 2019 data, to obtain the incidence, mortality and disability adjusted life year (DALY) rates and corresponding standardized indexes of dementia in China, USA, Japan, India, Malaysia, and the global in 1990-2019. Using Joinpoint to calculate annual percent change (APC) and average annual percent change (AAPC) of standardized incidence and mortality rate of dementia and compare the characteristics and trends of the burden of dementia with the development of years.  Results  In 2019, the incidence, mortality and DALY rate of dementia in China were higher in females than in males and higher in senior age groups than in lower age groups. From 1990 to 2019, the incidence, mortality and disability adjusted life year rate of dementia in China increased from 43.32/100 000, 7.88/100 000, 155.95/100 000 in 1990 to 126.57/100 000, 22.55/100 000, 420.22/100 000 in 2019, respectively. In 2019, the standardized incidence, standardized mortality and standardized DALY rate were higher than those in the global but lower than those in Japan. The standardized incidence rate of dementia in China has increased by 0.47% per year, and the standardized mortality rate has not changed significantly. The main risk factors of dementia in men and women were smoking, high BMI and high fasting plasma glucose in 2019.  Conclusions  Since 1990, the burden of dementia in China has been on the rise. Health education should be conducted to improve the public knowledge about the prevention of dementia, especially paying attention to the prevention and control of the elderly. People should formulate reasonable policies and control risk factors to further reduce the burden of dementia in China.
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