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CN 34-1304/RISSN 1674-3679

Volume 28 Issue 10
Oct.  2024
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ZHU Feiyun, YANG Ying, PAN Mengshan, YIN Tongle, XU Jiamin, CHEN Rucheng, ZHENG Weijun. Association between sarcopenia and all-cause mortality: a study based on 2011-2020 CHARLS data[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2024, 28(10): 1170-1175. doi: 10.16462/j.cnki.zhjbkz.2024.10.009
Citation: ZHU Feiyun, YANG Ying, PAN Mengshan, YIN Tongle, XU Jiamin, CHEN Rucheng, ZHENG Weijun. Association between sarcopenia and all-cause mortality: a study based on 2011-2020 CHARLS data[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2024, 28(10): 1170-1175. doi: 10.16462/j.cnki.zhjbkz.2024.10.009

Association between sarcopenia and all-cause mortality: a study based on 2011-2020 CHARLS data

doi: 10.16462/j.cnki.zhjbkz.2024.10.009
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  • Corresponding author: ZHENG Weijun, E-mail: deardangjun@163.com
  • Received Date: 2024-01-31
  • Rev Recd Date: 2024-07-14
  • Available Online: 2024-12-11
  • Publish Date: 2024-10-10
  •   Objective  To explore the association between sarcopenia and all-cause mortality in adults aged 45 and older.  Methods  Data from the China health and retirement longitudinal study (CHARLS) from 2011-2020 were utilized. Sarcopenia was diagnosed according to the 2019 standards set by the Asian Working Group for Sarcopenia (AWGS). The logistic regression model was used to calculate the individual propensity score (PS), and then the inverse probability of treatment weighting (IPTW) method was employed to perform Cox proportional hazard regression model analysis.  Results  The study included 12 241 participants: 7 279 participants without sarcopenia, 3 036 with probable sarcopenia, and 1 926 with sarcopenia. After IPTW adjustment, participants with possible sarcopenia had a 46% increased risk of mortality (HR=1.46, 95% CI: 1.19-1.77) compared to those without sarcopenia, and participants with sarcopenia had a 99% increased risk (HR=1.99, 95% CI: 1.43-2.76).  Conclusions  This research underscores the significant impact of sarcopenia on the mortality risk within the Chinese population, highlighting that sarcopenia can significantly increase the risk of death in adults aged 45 and above.
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  • [1]
    Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people[J]. Age Ageing, 2010, 39(4): 412-423. DOI: 10.1093/ageing/afq034.
    [2]
    Cruz-Jentoft AJ, Sayer AA. Sarcopenia[J]. Lancet, 2019, 393(10191): 2636-2646. DOI: 10.1016/S0140-6736(19)31138-9.
    [3]
    Anker SD, Morley JE, von Haehling S. Welcome to the ICD-10 code for sarcopenia[J]. J Cachexia Sarcopeni, 2016, 7(5): 512-514. DOI: 10.1002/jcsm.12147.
    [4]
    Petermann-Rocha F, Balntzi V, Gray SR, et al. Global prevalence of sarcopenia and severe sarcopenia: a systematic review and meta-analysis[J]. J Cachexia Sarcopeni, 2022, 13(1): 86-99. DOI: 10.1002/jcsm.12783.
    [5]
    Angulo J, El Assar M, Rodríguez-Mañas L. Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults[J]. Mol Aspects Med, 2016, 50: 1-32. DOI: 10.1016/j.mam.2016.06.001.
    [6]
    Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis[J]. Age Ageing, 2019, 48(4): 601. DOI: 10.1093/ageing/afz046.
    [7]
    Chen LK, Woo J, Assantachai P, et al. Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment[J]. J Am Med Dir Assoc, 2020, 21(3): 300-307. e2. DOI: 10.1016/j.jamda.2019.12.012.
    [8]
    Zhao YH, Hu YS, Smith JP, et al. Cohort profile: the China health and retirement longitudinal study (CHARLS)[J]. Int J Epidemiol, 2014, 43(1): 61-68. DOI: 10.1093/ije/dys203.
    [9]
    Gao K, Cao LF, Ma WZ, et al. Association between sarcopenia and cardiovascular disease among middle-aged and older adults: findings from the China health and retirement longitudinal study[J]. EClinicalMedicine, 2022, 44: 101264. DOI: 10.1016/j.eclinm.2021.101264.
    [10]
    Lee SJ, Yang YJ, Lee DW, et al. Influence of sarcopenia on postoperative complications in patients undergoing autologous microsurgical breast reconstruction: an inverse probability of treatment weighting analysis[J]. Front Oncol, 2023, 13: 1211593. DOI: 10.3389/fonc.2023.1211593.
    [11]
    Tang TJ, Zhuo Y, Xie LL, et al. Sarcopenia index based on serum creatinine and cystatin C is associated with 3-year mortality in hospitalized older patients[J]. Sci Rep, 2020, 10(1): 1260. DOI: 10.1038/s41598-020-58304-z.
    [12]
    Sääksjärvi K, Härkänen T, Stenholm S, et al. Probable sarcopenia, obesity, and risk of all-cause mortality: a pooled analysis of 4 612 participants[J]. Gerontology, 2023, 69(6): 706-715. DOI: 10.1159/000527804.
    [13]
    Lin JA, Hou JD, Wu SY. Effect of sarcopenia on mortality in type 2 diabetes: a long-term follow-up propensity score-matched diabetes cohort study[J]. J Clin Med, 2022, 11(15): 4424. DOI: 10.3390/jcm11154424.
    [14]
    Colón-Emeric CS, McDermott CL, Lee DS, et al. Risk assessment and prevention of falls in older community-dwelling adults: a eview[J]. JAMA, 2024, 331(16): 1397-1406. DOI: 10.1001/jama.2024.1416.
    [15]
    Ganz DA, Latham NK. Fall prevention in community-dwelling older adults. Reply[J]. N Engl J Med, 2020, 382(26): 2581-2582. DOI: 10.1056/NEJMc2005662.
    [16]
    Liu DQ, Wang SJ, Liu S, et al. Frontiers in sarcopenia: advancements in diagnostics, molecular mechanisms, and therapeutic strategies[J]. Mol Aspects Med, 2024, 97: 101270. DOI: 10.1016/j.mam.2024.101270.
    [17]
    Yuan S, Larsson SC. Epidemiology of sarcopenia: prevalence, risk factors, and consequences[J]. Metabolism, 2023, 144: 155533. DOI: 10.1016/j.metabol.2023.155533.
    [18]
    Gingrich A, Volkert D, Kiesswetter E, et al. Prevalence and overlap of sarcopenia, frailty, cachexia and malnutrition in older medical inpatients[J]. BMC Geriatr, 2019, 19: 120. DOI: 10.1186/s12877-019-1115-1.
    [19]
    Beaudart C, Sanchez-Rodriguez D, Locquet M, et al. Malnutrition as a strong predictor of the onset of sarcopenia[J]. Nutrients, 2019, 11(12): 2883. DOI: 10.3390/nu11122883.
    [20]
    Ancum VMJ, Scheerman K, Jonkman NH, et al. Change in muscle strength and muscle mass in older hospitalized patients: a systematic review and meta-analysis[J]. Exp Gerontol, 2017, 92: 34-41. DOI: 10.1016/j.exger.2017.03.006.
    [21]
    Gong G, Wan WH, Zhang XH, et al. Correlation between the Charlson comorbidity index and skeletal muscle mass/physical performance in hospitalized older people potentially suffering from sarcopenia[J]. BMC Geriatr, 2019, 19(1): 367. DOI: 10.1186/s12877-019-1395-5.
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