母亲妊娠期和围生期因素与青少年血压的关系

李玉艳; 武俊青; 赵瑞; 任静朝; 戎芬; 周颖; 纪红蕾; 高尔生

doi:10.16462/j.cnki.zhjbkz.2016.01.009

母亲妊娠期和围生期因素与青少年血压的关系

doi: 10.16462/j.cnki.zhjbkz.2016.01.009

1. 上海市计划生育科学研究所/国家卫计委计划生育药具重点实验室, 上海 200032;
2. 新乡医学院公共卫生学院流行病与卫生统计学教研室, 河南新乡 453003;
3. 上海中医药大学基础医学院预防医学教研室, 上海 201203

基金项目:

国家自然科学基金（81072364）

详细信息

作者简介:
李玉艳(1979-),女,山东平邑人,副研究员,博士。主要研究方向:生殖健康流行病学。

中图分类号: R179;R544
计量
- 文章访问数: 326
- HTML全文浏览量: 95
- PDF下载量: 131
- 被引次数: 0
出版历程
- 收稿日期: 2015-10-08
- 修回日期: 2015-11-28

The relationship between maternal gestational and perinatal factors and blood pressure among adolescents

1. Shanghai Institute of Planned Parenthood Research/Key Laboratory of Contraceptive Device of National Population and Family Planning Commission, Shanghai 200032, China;
2. Department of Epidemiology and Statistics, School of Public Health, Xinxiang Medicine University, Xinxiang 453003, China;
3. Department of Preventive Medicine, School of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

摘要

摘要: 目的探讨母亲妊娠期因素和围生期因素与子女青少年期血压之间的关系。方法对1993-1995年无锡市建立的出生队列于2011-2013年（青少年期）进行随访，开展问卷调查、身高、体重和血压的测量，采用χ²检验、多元线性回归分析、多因素二项式回归等统计方法进行数据分析。结果共随访到年龄16～18岁之间的青少年2 256人。调整性别、青少年期年龄、青少年期超重或肥胖、青少年期生活行为因素，将母亲妊娠期和围生期相关变量纳入多因素模型，结果显示：母亲产时有妊高症的对象，青少年期的收缩压和舒张压升高，“血压升高比例”增加（RR=1.54，95% CI：1.26～1.90）；随着出生身长的增加，青少年的收缩压升高。结论母亲产时妊高症是子女青少年期血压升高的危险因素，应采取一定的措施，控制妊高症的发生。
- 孕妇 /
- 青少年 /
- 血压
Abstract: Objective To explore the relationship between maternal gestational and perinatal factors and blood pressure (BP) among adolescents. Methods A follow-up study for the birth cohort from 1993 to 1995 in Wuxi was conducted during 2011 to 2013. Questionnaire survey and physical examination, including height, weight, systolic blood pressure (SBP) and diastolic blood pressure (DBP), were conducted. The χ² test, multi-linear regression and multi-genmod model were used to analyze the data. Results A total of 2 256 adolescents aged from 16 to 18 were followed up. After adjusting sex, age and overweight and obesity in adolescence, life habits of adolescents, the maternal gestational and perinatal factors were analyzed in the multi-models. We found that compared with adolescents whose mother had no pregnancy-induced hypertension when delivery, those whose mother had pregnancy-induced hypertension had higher SBP, DBP and the proportion of elevated BP (RR=1.54, 95% CI: 1.26-1.90). And the SBP of adolescents increased along with the increase of birth body length. Conclusions Pregnancy-induced hypertension when delivery was a risk factor of blood pressure for adolescents. Some methods should be conducted to prevent the pregnancy-induced hypertension.
- Pregnant woman /
- Adolescent /
- Blood pressure

HTML全文

参考文献(18)

卫生部心血管疾病防治研究中心. 中国心血管病报告2008-2009 [M]. 北京:中国大百科全书出版社, 2010.

Luma GB, Spiotta RT. Hypertension in children and adolescents [J]. Am Fam Physician, 2006,73(9):1558-1568.

范华. 泰安市青少年血压分布及高血压影响因素调查 [D]. 泰安:泰山医学院, 2007.

Tian JY, Cheng Q, Song XM, et al. Birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults [J]. Eur J Endocrinol, 2006,155(4):601-607.

米杰,王天有,孟玲慧,等. 中国儿童青少年血压参照标准的研究制定 [J]. 中国循证儿科杂志, 2010,5(1):4-14.

Wells JC, Hallal PC, Reichert FF, et al. Sleep patterns and television viewing in relation to obesity and blood pressure: evidence from an adolescent Brazilian birth cohort [J]. Int J Obes, 2008,32(7):1042-1049.

李伟荣,翟屹,沈冲,等. 我国三省7~13岁儿童血压升高影响因素的初步分析 [J]. 中华疾病控制杂志, 2011,15(11):931-934.

中国肥胖问题工作组,季成叶. 中国学龄儿童青少年超重、肥胖筛查体质指数值分类标准 [J]. 中华流行病学杂志, 2004,25(2):97-102.

Barker DJ, Osmond C. Infant mortality, childhood nutrition, and ischaemic heart disease in England and Wales [J]. Lancet, 1986,1 (8489):1077-1081.

Lawlor DA, Najman JM, Sterne J, et al. Associations of parental, birth, and early life characteristics with systolic blood pressure at 5 years of age: findings from the Mater-University study of pregnancy and its outcomes [J]. Circulation, 2004,110(16):2417-2423.

Martin RM, Ness AR, Gunnell D, et al. Does breast-feeding in infancy lower blood pressure in childhood? The Avon Longitudinal Study of Parents and Children (ALSPAC) [J]. Circulation, 2004, 109(10):1259-1266.

王新利,崔蕴璞,童笑梅,等. 妊娠高血压综合征对足月新生儿胰岛素敏感性的影响 [J]. 中国儿童保健杂志, 2004,12(1):37-40.

孟海霞. 妊娠期高血压与围产期结局的关系研究 [J]. 实用临床医药杂志, 2013,17(11):153-154.

冯永亮,彭婷婷,王芳,等. 妊娠期高血压疾病对出生结局的影响及相关因素 [J]. 中华疾病控制杂志, 2014,18(2):131-134.

Falkner B, Hulman S, Kushner H. Effect of birth weight on blood pressure and body size in early adolescence [J]. Hypertension, 2004,43(2):203-207.

Huxley RR, Shiell AW, Law CM. The role of size at birth and postnatal catch-up growth in determining systolic blood pressure: a systematic review of the literature [J]. J Hypertens, 2000,18(7):815-831.

Menezes AM, Hallal PC, Horta BL, et al. Size at birth and blood pressure in early adolescence: a prospective birth cohort study [J]. Am J Epidemiol, 2007,165(6):611-616.

卞晓云,王兴纬,奚正荣,等. 巨大儿青少年期生长发育和多元代谢特征 [J]. 江苏医药, 2008,34(12):1233-1234.

施引文献

资源附件(0)

访问统计