孕前BMI及孕期体育活动与妊娠期糖尿病的关系

解冰洁; 郭朋鸽; 彭婷婷; 岳福娟; 王芳; 冯永亮; 邬惟为; 杨海澜; 王素萍; 张亚玮

doi:10.16462/j.cnki.zhjbkz.2016.04.010

孕前BMI及孕期体育活动与妊娠期糖尿病的关系

doi: 10.16462/j.cnki.zhjbkz.2016.04.010

1. 山西医科大学公共卫生学院流行病学教研室, 山西太原 030001;
2. 山西医科大学第一医院妇产科, 山西太原 030001;
3. 耶鲁大学公共卫生学院环境健康科学系, 美国纽黑文 CT06410

基金项目:

国家自然科学基金（81473061）；山西医科大学十人计划项目（2015年）；山西省青年科技研究基金（2013021033-2）

详细信息

作者简介:
解冰洁(1990-),女,山西运城人,在读硕士研究生。主要研究方向:环境流行病学与生殖健康。

中图分类号: R587.1;R714.14
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出版历程
- 收稿日期: 2015-11-08
- 修回日期: 2016-01-09

Pre-pregnancy body mass index, physical activity during pregnancy and risk of the gestational diabetes mellitus

1. Department of Epidemiology, Shanxi Medical University, Taiyuan 030001, China;
2. Obstetrics and Gynecology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China;
3. Division of Environmental Health Sciences, School of Public Health, Yale University, New Haven CT06410, USA

摘要

摘要: 目的探讨孕前体质指数（body mass index，BMI）及孕期体育活动与妊娠期糖尿病的关系。方法将2012年3月～2014年12月在山西医科大学第一医院产科分娩的6 211例单胎孕妇作为研究对象，根据孕前BMI和体育活动分组，采用非条件Logistic回归分析妊娠期糖尿病发生的影响因素。结果 6 211例孕妇妊娠期糖尿病（gestational diabetes mellitus，GDM）的发生率为16.02%（995/6 211）。孕前超重和肥胖者GDM发生率高于孕前BMI正常范围的孕妇（OR=2.288，95% CI:1.946～2.691）；孕前BMI较低者GDM的发生率低于孕前BMI正常范围的孕妇（OR=0.692，95% CI:0.541～0.885）；未发现体育活动与妊娠期糖尿病有关。孕前BMI与孕期体育活动间不存在交互作用（OR=0.899，95% CI:0.370～1.534）。结论孕前超重和肥胖是GDM发生的危险因素，因此孕妇应合理地控制孕前BMI以减少妊娠期糖尿病的发生。
- 人体质量指数 /
- 体育运动 /
- 糖尿病,妊娠
Abstract: Objective The study aims to investigate the relationship between maternal prepregnancy body mass index(BMI), physical activity during pregnancy and the gestational diabetes mellitus (GDM). Methods A birth cohort study,which including 6 211 pregnant women with single birth, was conducted from March 2012 to December 2014 in the First Affiliated Hospital of Shanxi Medical University. Information on birth outcomes and maternal complications were abstracted from medical records. Multivariate unconditional logistic regression models were employed to estimate the associations between pre-pregnancy BMI and GDM. Results A total of 16.02%(995/6 211) women were diagnosed with GDM. The risk of GDM in obese and overweight pregnant women was higher than that in normal BMI pregnant women (OR=2.288,95% CI:1.946-2.691), but the risk of GDM in underweight pregnant women was lower (OR=0.692,95%CI:0.541-0.885). The association between physical activity during pregnancy and the risk of GDM had not been found. We also did not observe significant interactions between pre-pregnancy BMI and physical activity during pregnancy (OR=0.899,95% CI:0.370-1.534). Conclusions High pre-pregnancy BMI may be a risk factor of GDM, and keeping normal pre-pregnancy BMI is a better way to prevent GDM.
- Body mass index /
- Sports /
- Diabetes,gestational

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参考文献(14)

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