Abstract: Objective To assess the smoking status of migrant workers, toexplore the impact of migrant characteristics and psychological state on them in manufacturing factories in Guangdong Province, and to provide reference for further tobacco control measures. Methods In a cross-sectional study between April and December 2012, 888 migrant workers in 10 factories from 4 cities were selected. A structured questionnaire was used to assess the smoking status and explore the associated factors of smoking behaviors. One-way and Logistic regression analysis were used to explore the associated factors. Results Current smoking rate of migrant workers was high (42.2%). Migrants who were single or divorced,senior high school educated and worked in more than 3 migratory cities were more likely to smoke. Workers who are in better psychological condition and migrate with families were less likely to smoke. Conclusions Migrant characteristics, and psychological state are associated with current smoking behaviors. The identifications of risk factors for current smoking may help to target health promotion interventions and decrease health risk of tobacco.