A cross-sectional study on hepatitis B infection of migrant workers in Zhangjiagang City
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摘要: 目的 掌握张家港市流动人口乙型肝炎病毒感染状况，为今后乙型肝炎防治工作提供科学依据。方法 采用单纯随机抽样，利用酶联免疫吸附试验方法检测乙肝表面抗原（hepatitis B surface antigen，HBsAg）和乙肝表面抗体（hepatitis B surface antibody，HBsAb）。结果 共调查张家港市流动人口1 516人，男性占69.0%，中青年居多。HBsAg总阳性粗率为9.6%，性别差异无统计学意义（χ2=0.06,P=0.851），而不同年龄组间差异有统计学意义（χ2=9.37，P=0.015）。HBsAb总阳性率为50.9%，男性高于女性（χ2=7.31，P=0.007）。不同性别、不同年龄组间乙肝疫苗接种率差异有统计学意义（均有P<0.05）；有乙肝疫苗接种史者，其HBsAg阳性率降低（OR=1.64，95% CI：1.15~2.34，P=0.006）。结论 张家港市流动人口感染状况调查在乙型肝炎的传播流行上具有重要意义。加强乙型肝炎的健康教育，提倡良好的卫生习惯，推行免疫接种，是预防乙型肝炎传播流行的必要和切实可行的措施。Abstract: Objective To study the prevalence of hepatitis B of migrant workers in Zhangjiagang City and provide scientific evidences for hepatitis B prevention and control. Methods Sample random sampling was conducted and enzyme-linked immunosorbent assay was used to recognize hepatitis B surface antigen (HBsAg) and Hepatitis B surface antibody (HBsAb). Results A total of 1 516 migrant workers were investigated, men accounted for 69.0%, most of them were young and middle-aged. The positive rate of HBsAg was 9.6% and no significant difference was found between men and women. However, it was found among various age groups (χ2=9.37,P=0.015). The positive rate of HBsAb was 50.9% and men was higher than women (χ2=7.31,P=0.007). There were significant differences in hepatitis B vaccine coverage rate between gender and among various age groups (all P<0.05), the HBsAg positive rate of subjects who were vaccinated had significantly decreased (OR=1.64,95% CI:1.15-2.34,P=0.006). Conclusions The investigation is of great importance in spread of hepatitis B. Associated health education and vaccination promotion are necessary and feasible measures to prevent the further transmission of hepatitis B.
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Key words:
- Hepatitis B /
- Infection /
- Epidemiologic methods
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