A study on dropping-out rate and associated factors of patients with methadone maintenance treatment in Beijing from 2010 to 2014
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摘要: 目的 了解北京市美沙酮维持治疗（methadone maintenance treatment, MMT）人员脱失情况及影响因素。方法 利用北京市“社区MMT系统”收集2010年1月1日～2014年12月31日期间入组的病例资料，运用SPSS 18.0进行统计分析。结果 共收集病例1 923例，脱失率为42.38%。离异或丧偶者与已婚有配偶者相比，脱失风险较高（OR=1.47，95% CI：1.11～1.99）；与吸毒朋友交往的频率中，经常（OR=1.45，95% CI：1.05～2.01）、每天（OR=1.86，95% CI：1.34～2.59）与偶尔交往者相比，脱失风险较高；参加治疗天数≤720 d者与>720 d者相比，脱失风险较高，其中参加治疗31～90 d者（OR=22.25，95% CI：12.38～39.96）脱失风险最大；治疗期间尿检阳性率越高，脱失风险越大。结论 MMT门诊应加强服药期间尿吗啡检查，对于尿检阳性率高、参加治疗时间短的患者加强心理行为干预，从而降低脱失率。Abstract: Objective To study on dropping-out rate and associated influencing factors of patients with methadone maintenance treatment (MMT) in Beijing from 2010 to 2014. Methods Cases were collected from MMT information system from January 1st, 2010 to December 31st, 2014 with detailed information and analyzed with SPSS 18.0. Results 1 923 cases were included in total and the dropping-out rate was 42.38%. It showed that the divorced or widowed had higher dropping-out risk compared with the married (OR=1.47,95% CI:1.11-1.99). In the way of contact frequency with drug addicts, cases contacted with drug addicts often(OR=1.45,95% CI:1.05-2.01) or daily(OR=1.86, 95% CI:1.34-2.59)had higher dropping-out risk than occasional contact, cases who were treated less than 720 days had higher dropping-out risk than those who above 720 days, and treatment time during 31-90 days(OR=22.25,95% CI：12.38-39.96)was with the highest dropping-out risk . During the treatment,the higher positive rate of urine test, the greater the risk of dropping-out. Conclusions MMT clinics should increase urine morphine test during the medicine using and we should strengthen the psychological behavior intervention especially on those whose treatment time is too short and with high positive rate of urine test to reduce dropping-out rate .
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Key words:
- Methadone /
- Therapy /
- Risk factors
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