Epidemiological analysis on severe fever with thrombocytopenia syndrome in Anhui Province, 2011-2015
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摘要: 目的 了解安徽省发热伴血小板减少综合征（severe fever with thrombocytopenia syndrome,SFTS）的流行特征，为该病的预防控制提供科学依据。方法 用描述性研究方法对2011-2015年安徽省发热伴血小板减少综合征监测数据进行系统分析。结果 2011-2015年，安徽省医疗机构报告SFTS 575例，占报告病例总数的84.19%（575/683）。5年间,报告病例数不断增多，报告发病率呈上升趋势（χ趋势2=217.56，P<0.001），但病死率却在下降。实验室诊断病例共330例，主要分布在安徽省中部地区；从3月份开始流行，5～7月为病例报告高峰；男女性别比约为1.14：1；发病年龄集中在40～74岁年龄组（87.27%），并且报告的死亡病例全部集中在此年龄组；职业分布以农民为主（87.27%）。聚集性疫情发生最可能的因素是接触死者的血液和分泌物。结论 发热伴血小板减少综合征报告病例在安徽省分布广泛，报告病例数逐年上升，发病具有明显的季节性。因此，要做好重点地区、高危人群的监测和防控工作。Abstract: Objective To understand the epidemiological characteristics of severe fever with thrombocytopenia syndrome (SFTS) in Anhui Province, and to provide scientific evidence for the disease control and prevention. Methods A descriptive epidemiological study method was used to analyze the surveillance data of SFTS in Anhui Province during 2011 to 2015. Results The vast majority of cases (575 cases, 84.19%) of SFTS were reported by medical institutions in Anhui province from 2011 to 2015. As the number of reported SFTS cases continuously increased, its incidence was on the rise. But the case fatality rate (CFR) had steadily decreased. There were 330 cases confirmed by laboratory. These cases were mainly reported in the middle area of Anhui province. Every year the prevalence began at March and the peak of occurrence was from May to July. Among these cases, the ratio of male to female was 1.14:1. The majority (87.27%) were 40 to 74 years old, which included all of the deaths. 87.27% were farmers. The family clusters of SFTSV infections were most likely to result from contacting the blood and secretions of the index case. Conclusions SFTS reported cases exist widely in Anhui province and the reported cases increase year by year and the incidence time mainly concentrated from May to July. Therefore, we must work on the surveillance and prevention of SFTS among high risk population in high-risk area.
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Key words:
- Case reports /
- Population surveillance /
- Epidemiologic studies
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Zhang X, Liu Y, Zhao L, et al. An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV [J]. Sci China Life Sci, 2013,56(8):697-700. Liu Q, He B, Huang SY, et al. Severe fever with thrombocytopenia syndrome, an emerging tick-borne zoonosis [J]. Lancet Infect Dis, 2014,14(8):763-772. Yu XJ, Liang MF, Zhang SY, et al. Fever with thrombocytopenia associated with a novel bunyavirus in China [J]. N Engl J Med, 2011,364(16):1523-1532. Kim KH, Yi J, Kim G, et al. Severe fever with thrombocytopenia syndrome, South Korea, 2012 [J]. Emerg Infect Dis, 2013,19(11):1892-1894. Takahashi T, Maeda K, Suzuki T, et al. The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan [J]. J Infect Dis, 2014,209(6):816-827. 李昱,周航,牟笛,等. 中国2011-2014年发热伴血小板减少综合征流行特征分析 [J]. 中华流行病学杂志, 2015,36(6):598-602. Pan H, Hu J, Liu S, et al. A reported death case of a novel bunyavirus in Shanghai, China [J]. Virol J, 2013,10(6):187-192. Liu K, Zhou H, Sun RX, et al. A national assessment of the epidemiology of severe Fever with thrombocytopenia syndrome,china [J]. Sci Rep, 2015,5(9):679-687. Sun J, Chai C, Lv H, et al. Epidemiological characteristics of severe fever with thrombocytopenia syndrome in Zhejiang Province,China [J]. Int J Infect Dis, 2014,25(8):180-185. Ding S, Niu G, Xu X, et al. Age is a critical risk factor for severe fever with thrombocytopenia syndrome [J]. PLoS One, 2014,9(11):1736-1740. 吕勇,吴家兵,徐鹏鹏,等. 皖西地区发热伴血小板减少综合征人传人疫情调查 [J]. 中国公共卫生, 2014,30(9):1129-1132. 程周祥,王斐,钱帮群,等. 皖南地区首起人传聚集性发热伴血小板减少综合征疫情的调查处置 [J]. 中华疾病控制杂志, 2014,18(11):1055-1058. Bao CJ,Guo XL,Qi X, et al. A family cluster of infections by a newly recognized bunyavirus in eastern China,2007:further evidence of person-to-person transmission [J]. Clin Infect Dis, 2011,53(12):1208-1214. Liu Y, Li Q, Hu W, et al. Person-to-person transmission of severe fever with thrombocytopenia syndrome virus [J]. Vector Borne Zoonotic Dis, 2012,12(2):156-160. Gai Z, Liang M, Zhang Y, et al. Person-to-person transmission of severe fever with thrombocytopenia syndrome bunyavirus through blood contact [J]. Clin Infect Dis, 2012,54(2):249-252. Kim WY, Choi W, Park SW, et al. Nosocomial transmission of severe fever with thrombocytopenia syndrome in Korea [J]. Clin Infect Dis, 2015,60(11):1681-1683. Ye L, Shang X, Wang Z, et al. A case of severe fever with thrombocytopenia syndrome caused by a novel bunyavirus in Zhejiang, China [J]. Int J Infect Dis, 2015,33(4):199-201. Zhang L, Sun J, Yan J, et al. Antibodies against severe fever with thrombocytopenia syndrome virus in healthy persons, China,2013 [J]. Emerg Infect Dis, 2014,20(8):1355-1357. 期刊类型引用(21)
1. 滕雪娇，邓舒，赵玉秋，丁中兴，李笑颜，吴家兵. 2011-2022年安徽省发热伴血小板减少综合征流行特征分析. 疾病监测. 2024(01): 48-52 . 
百度学术2. 路静，卞光玲. 2017—2022年连云港市海州区发热伴血小板减少综合征流行特征及聚集性疫情分析. 江苏卫生保健. 2024(01): 20-21+26 . 百度学术3. 董棒，褚雨，单晨啸，张旭，苗璨，缪玉丹，杨玉法. 枣庄市27例发热伴血小板减少综合征患者流行病学及临床特征分析. 中华卫生杀虫药械. 2024(01): 59-61 . 百度学术4. 冀国霞，袁芳，尹旋旋. 2012—2022年青州市发热伴血小板减少综合征流行病学特征分析. 微生物学免疫学进展. 2024(03): 66-70 . 百度学术5. 叶正文，温克雨，张为顺. 巢湖市2018—2022年发热伴血小板减少综合征流行病学调查分析. 安徽预防医学杂志. 2023(03): 209-212+262 . 百度学术6. 孙琦，张国英，高永伟. 运用集中度和圆形分布法分析山东省威海市发热伴血小板减少综合征的季节性特征. 中国媒介生物学及控制杂志. 2023(06): 794-798 . 百度学术7. 段青，逄博，张晓梅，田雪莹，张玉薇，邢玉芳，丁淑军，寇增强，姜晓林. 2011-2020年山东省发热伴血小板减少综合征流行特征及空间聚集性. 中华疾病控制杂志. 2022(07): 790-797 . 本站查看8. 雷新军，孔金屏，熊进峰，谭梁飞. 发热伴血小板减少综合征的流行病学特征及其与蜱密度消长的关系. 上海预防医学. 2022(07): 646-649 . 百度学术9. 马涛，张敏，杜雪飞，汪君君，王恒学，徐庆，周沁易，郑颖，林丹，洪镭，刘坤. 发热伴血小板减少综合征疫情呈上升趋势:基于2015―2020年南京市报告病例数据. 中华疾病控制杂志. 2022(12): 1407-1413 . 本站查看10. 王敬忠，陈宏标，彭志强，陈琦. 广东省首例输入性发热伴血小板减少综合征病例调查. 中国感染控制杂志. 2021(01): 86-90 . 百度学术11. 张寿锋，王慧. 2014—2019年山东省沂源县发热伴血小板减少综合征流行特征分析. 上海预防医学. 2021(12): 1146-1149 . 百度学术12. 张强，王文靖，刘振武，刘旭祥，赵科伕，张磊，凤翀，吴金菊. 合肥市发热伴血小板减少综合征实验室确诊病例临床资料分析. 安徽预防医学杂志. 2021(06): 441-444+506 . 百度学术13. 张鸿雁，陈桂榴，李文庭，冷瑞雪，秦薇子. 不同预后的发热伴血小板减少综合征重症患者临床实验室指标对比分析. 中华疾病控制杂志. 2020(03): 365-368 . 本站查看14. 宋丹丹，龚磊，吴家兵，曹明华，张永根，刘一梅，张勇，汪金生，杨明，徐鹏鹏，高伟林. 安徽省发热伴血小板减少综合征部分流行地区蜱类分布调查. 安徽预防医学杂志. 2020(04): 267-269+280 . 百度学术15. 曹明华. 发热伴血小板减少综合征流行病学进展. 安徽预防医学杂志. 2020(06): 444-446+463 . 百度学术16. 汪金生，龚磊，李贤相，高伟林，宋丹丹，徐四清. 安庆市137例发热伴血小板减少综合征流行病学调查及传播媒介蜱虫监测结果. 职业与健康. 2019(04): 516-520 . 百度学术17. 宋玉华，孙美兰，温克雨. 巢湖市2011～2017年发热伴血小板减少综合征流行特征分析. 安徽预防医学杂志. 2018(03): 184-187 . 百度学术18. 汪金生，汤厚林，高伟林，李贤相，徐四清，姜荣明. 2011-2016年安徽省安庆市发热伴血小板减少综合征监测分析. 疾病监测. 2018(04): 324-328 . 百度学术19. 杨旻，叶珺，李惠，华天凤，郑瑶，李俊. 69例发热伴血小板减少综合征临床特点及预后影响因素的调查研究. 中华疾病控制杂志. 2018(04): 402-405 . 本站查看20. 解少煜，吕勇，孙婕，徐鹏鹏，常宏伟，秦伟，李开春，胡颉颖，袁伟，俞亮，谢华，李光江，杨承武，张丽梅，张凤，丁凡，王芹，李德新，王德斌. 皖西地区发热伴血小板减少综合征现状调查. 安徽医科大学学报. 2018(03): 386-389 . 百度学术21. 马涛，徐庆，李晨，张钟，丰罗菊，李伟，许阳婷，随海田，洪镭. 2010-2016年南京市发热伴血小板减少综合征流行特征分析. 现代预防医学. 2017(16): 2890-2894 . 百度学术其他类型引用(8)
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