安徽省2011-2015年发热伴血小板减少综合征流行特征分析

曹琛; 吴家兵; 曹明华; 陈国平; 宋丹丹; 王建军

doi:10.16462/j.cnki.zhjbkz.2016.08.010

安徽省2011-2015年发热伴血小板减少综合征流行特征分析

doi: 10.16462/j.cnki.zhjbkz.2016.08.010

1. 安徽医科大学公共卫生学院流行病与卫生统计学系, 安徽合肥 230032;
2. 安徽省疾病预防控制中心卫生应急管理与急性传染病防治科, 安徽合肥 230601

详细信息

作者简介:
曹琛(1989-),女,安徽怀远人,在读硕士研究生。主要研究方向:传染性疾病预防与控制。

中图分类号: R181.22
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出版历程
- 收稿日期: 2016-03-11
- 修回日期: 2016-05-18

Epidemiological analysis on severe fever with thrombocytopenia syndrome in Anhui Province, 2011-2015

1. Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei 230032, China;
2. Department of Acute Infectious Disease Prevention, Anhui Provincial Center for Disease Control and Prevention, Hefei 230601, China

摘要

摘要: 目的了解安徽省发热伴血小板减少综合征（severe fever with thrombocytopenia syndrome,SFTS）的流行特征，为该病的预防控制提供科学依据。方法用描述性研究方法对2011-2015年安徽省发热伴血小板减少综合征监测数据进行系统分析。结果 2011-2015年，安徽省医疗机构报告SFTS 575例，占报告病例总数的84.19%（575/683）。5年间,报告病例数不断增多，报告发病率呈上升趋势（χ_趋势²=217.56，P<0.001），但病死率却在下降。实验室诊断病例共330例，主要分布在安徽省中部地区；从3月份开始流行，5～7月为病例报告高峰；男女性别比约为1.14：1；发病年龄集中在40～74岁年龄组（87.27%），并且报告的死亡病例全部集中在此年龄组；职业分布以农民为主（87.27%）。聚集性疫情发生最可能的因素是接触死者的血液和分泌物。结论发热伴血小板减少综合征报告病例在安徽省分布广泛，报告病例数逐年上升，发病具有明显的季节性。因此，要做好重点地区、高危人群的监测和防控工作。
- 病例报告 /
- 人群监测 /
- 流行病学研究
Abstract: Objective To understand the epidemiological characteristics of severe fever with thrombocytopenia syndrome (SFTS) in Anhui Province, and to provide scientific evidence for the disease control and prevention. Methods A descriptive epidemiological study method was used to analyze the surveillance data of SFTS in Anhui Province during 2011 to 2015. Results The vast majority of cases (575 cases, 84.19%) of SFTS were reported by medical institutions in Anhui province from 2011 to 2015. As the number of reported SFTS cases continuously increased, its incidence was on the rise. But the case fatality rate (CFR) had steadily decreased. There were 330 cases confirmed by laboratory. These cases were mainly reported in the middle area of Anhui province. Every year the prevalence began at March and the peak of occurrence was from May to July. Among these cases, the ratio of male to female was 1.14:1. The majority (87.27%) were 40 to 74 years old, which included all of the deaths. 87.27% were farmers. The family clusters of SFTSV infections were most likely to result from contacting the blood and secretions of the index case. Conclusions SFTS reported cases exist widely in Anhui province and the reported cases increase year by year and the incidence time mainly concentrated from May to July. Therefore, we must work on the surveillance and prevention of SFTS among high risk population in high-risk area.
- Case reports /
- Population surveillance /
- Epidemiologic studies

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参考文献(18)

Zhang X, Liu Y, Zhao L, et al. An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV [J]. Sci China Life Sci, 2013,56(8):697-700.

Liu Q, He B, Huang SY, et al. Severe fever with thrombocytopenia syndrome, an emerging tick-borne zoonosis [J]. Lancet Infect Dis, 2014,14(8):763-772.

Yu XJ, Liang MF, Zhang SY, et al. Fever with thrombocytopenia associated with a novel bunyavirus in China [J]. N Engl J Med, 2011,364(16):1523-1532.

Kim KH, Yi J, Kim G, et al. Severe fever with thrombocytopenia syndrome, South Korea, 2012 [J]. Emerg Infect Dis, 2013,19(11):1892-1894.

Takahashi T, Maeda K, Suzuki T, et al. The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan [J]. J Infect Dis, 2014,209(6):816-827.

李昱,周航,牟笛,等. 中国2011-2014年发热伴血小板减少综合征流行特征分析 [J]. 中华流行病学杂志, 2015,36(6):598-602.

Pan H, Hu J, Liu S, et al. A reported death case of a novel bunyavirus in Shanghai, China [J]. Virol J, 2013,10(6):187-192.

Liu K, Zhou H, Sun RX, et al. A national assessment of the epidemiology of severe Fever with thrombocytopenia syndrome,china [J]. Sci Rep, 2015,5(9):679-687.

Sun J, Chai C, Lv H, et al. Epidemiological characteristics of severe fever with thrombocytopenia syndrome in Zhejiang Province,China [J]. Int J Infect Dis, 2014,25(8):180-185.

Ding S, Niu G, Xu X, et al. Age is a critical risk factor for severe fever with thrombocytopenia syndrome [J]. PLoS One, 2014,9(11):1736-1740.

吕勇,吴家兵,徐鹏鹏,等. 皖西地区发热伴血小板减少综合征人传人疫情调查 [J]. 中国公共卫生, 2014,30(9):1129-1132.

程周祥,王斐,钱帮群,等. 皖南地区首起人传聚集性发热伴血小板减少综合征疫情的调查处置 [J]. 中华疾病控制杂志, 2014,18(11):1055-1058.

Bao CJ,Guo XL,Qi X, et al. A family cluster of infections by a newly recognized bunyavirus in eastern China,2007:further evidence of person-to-person transmission [J]. Clin Infect Dis, 2011,53(12):1208-1214.

Liu Y, Li Q, Hu W, et al. Person-to-person transmission of severe fever with thrombocytopenia syndrome virus [J]. Vector Borne Zoonotic Dis, 2012,12(2):156-160.

Gai Z, Liang M, Zhang Y, et al. Person-to-person transmission of severe fever with thrombocytopenia syndrome bunyavirus through blood contact [J]. Clin Infect Dis, 2012,54(2):249-252.

Kim WY, Choi W, Park SW, et al. Nosocomial transmission of severe fever with thrombocytopenia syndrome in Korea [J]. Clin Infect Dis, 2015,60(11):1681-1683.

Ye L, Shang X, Wang Z, et al. A case of severe fever with thrombocytopenia syndrome caused by a novel bunyavirus in Zhejiang, China [J]. Int J Infect Dis, 2015,33(4):199-201.

Zhang L, Sun J, Yan J, et al. Antibodies against severe fever with thrombocytopenia syndrome virus in healthy persons, China,2013 [J]. Emerg Infect Dis, 2014,20(8):1355-1357.

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