Prevalence of H-type hypertension and its risk factors among residents aged 35 years and older in Minhang District of Shanghai
-
摘要: 目的 了解上海市闵行区≥35岁人群H型高血压的患病情况及其影响因素。方法 采用多阶段随机抽样的方法选择≥35岁的常住居民进行问卷调查、身体测量和实验室检查,用多因素Logistic回归分析H型高血压患病的影响因素。结果 本研究获得有效数据3 059人。≥35岁人群的H型高血压患病率为47.04%,H型高血压占高血压患者的比例为87.95%。多因素分析结果显示,男性(OR=1.44,95% CI:1.21~1.73)、年龄≥45岁(OR=2.05,95% CI:1.46~2.88)、超重(OR=1.67,95% CI:1.40~2.00)和肥胖(OR=2.80,95% CI:2.13~3.70)、血压级别≥2级(OR=13.42,95% CI:8.97~20.06)、患有糖尿病(OR=1.66,95% CI:1.35~2.04)、血清肌酐升高(OR=2.84,95% CI:1.35~5.99)、血清叶酸偏低(OR=1.46,95% CI:1.23~1.73)、血清维生素B12偏低(OR=1.22,95% CI:1.03~1.45)是H型高血压的危险因素。结论 上海市闵行区35岁及以上人群的H型高血压患病率高,有必要针对主要危险因素采取社区H型高血压的防控措施。Abstract: Objective To investigate the prevalence of H-type hypertension and its risk factors among residents aged 35 years and older in Minhang District of Shanghai. Methods A multistage randomized sampling method was used to select the participants. Questionnaires, physical measures and laboratory tests were conducted among all participants. Logistic regression model was used to analyze the influencing factors of H-type hypertension. Results A total of 3 059 valid data were obtained in the study. The prevalence of H-type hypertension was 47.04% in residents aged 35 years and older. Participants with H-type hypertension accounted for 87.95% of all patients with hypertension in Minhang District. Results of multivariate logistic regression analysis showed that male gender (OR=1.44, 95% CI:1.21-1.73), the age of 45 years and older (OR=2.05, 95% CI:1.46-2.88), overweight (OR=1.67, 95% CI:1.40-2.00) and fat (OR=2.80, 95% CI:2.13-3.70), hypertension grade 2 and 3 (OR=13.42, 95% CI:8.97-20.06), diabetes (OR=1.66, 95% CI:1.35-2.04), high creatinine (OR=2.84, 95% CI:1.35-5.99), low folic acid (OR=1.46, 95% CI:1.23-1.73) and low vitamin B12 levels (OR=1.22, 95% CI:1.03-1.45) were risk factors of H-type hypertension. Conclusions There was a high prevalence of H-type hypertension in residents of Minhang District. Intervention programs for risk factors should be carried out in community residents to prevent and control H-type hypertension.
-
Key words:
- Hypertension /
- Prevalence /
- Risk factors
-
Zhao D, Liu J, Wang W, et al. Epidemiological transition of stroke in China: twenty-one-year observational study from the Sino-MONICA-Beijing Project[J]. Stroke, 2008,39(6):1668-1674. Wald DS, Law M, Morris JK. Homocysteine and cardiovascular disease:evidence on causality from a meta-analysis[J]. BMJ, 2002,325(7374):1202. The Homocysteine Studies Collaboration. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis[J]. JAMA, 2002,288(16):2015-2022. 王雪茵,胡永华. 同型半胱氨酸代谢与脑卒中关系的研究进展[J]. 中华疾病控制杂志, 2013,17(11):988-992. Graham IM, Daly LE, Refsum HM, et al. Plasma homocysteine as a risk factor for vascular disease: the European Concerted Action Project[J]. JAMA, 1997,277(22):1775-1781. Lim U, Cassano PA. Homocysteine and blood pressure in the Third National Health and Nutrition Examination Survey, 1988-1994[J]. Am J Epidemiol, 2002,156(12):1105-1113. 张岩,霍勇. 伴同型半胱氨酸升高的高血压——"H型"高血压[J]. 心血管病学进展, 2011,32(1):3-6. 中国高血压防治指南修订委员会. 中国高血压防治指南2010[J]. 中华高血压杂志, 2011,19(8):701-708,709-743. 樊萌语,吕筠,何平平. 国际体力活动问卷中体力活动水平的计算方法[J]. 中华流行病学杂志, 2014,35(8):961-964. Ainsworth BE, Haskell WL, Whitt MC, et al. Compendium of physical activities:an update of activity codes and MET intensities[J]. Med Sci Sports Exerc, 2000,32(9 Suppl):498-504. 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2010年版)[M]. 北京:北京大学医学出版社, 2011,5. 中国成人血脂异常防治指南制定联合委员会. 中国成人血脂异常防治指南[J]. 中华心血管病杂志, 2007,35(5):390-419. 王薇,赵冬,刘军,等. 北京城乡人群1168例血浆同型半胱氨酸分布及相关因素研究[J]. 中华流行病学杂志, 2002,23(1):32-35. 黄海威,郭明辉,黄家星,等. 1020名社区人群同型半胱氨酸水平的调查和相关分析[J]. 中华流行病学杂志, 2006,27(8):721-724. 梁长流,蒋善群,彭少杰,等. MTHFR C677T基因多态性与高同型半胱氨酸型高血压关联性研究[J]. 中华疾病控制杂志, 2011,15(6):480-484. 陈磊,朱晓云. 上海市金山区H型高血压相关因素分析[J]. 上海预防医学, 2015,27(10):602-604. 汪国海,霍勇,王梦德,等. 轻中度高血压人群叶酸与同型半胱氨酸水平的相关性分析[J]. 疾病控制杂志, 2007,11(2):171-173. Lee M, Hong KS, Chang SC, et al. Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: a meta-analysis[J]. Stroke, 2010,41(6):1205-1212.
点击查看大图
计量
- 文章访问数: 386
- HTML全文浏览量: 127
- PDF下载量: 4
- 被引次数: 0