Abstract: Objective To understand the disease burden of stroke-related deaths among rural areas of Liaoning Province and to provide evidence for stroke prevention and treatment. Methods The all-cause mortality data and the demographic data of Zhangwu and Fengcheng areas in Liaoning province in 2013 were collected. Years of life lost (YLL), YLL rate, Age Standardized YLL rate, average years of life lost (AYLL), Age Standardized AYLLs and the change of YLL rate with age were calculated. Results Stroke YLL rate showed an increased trend with age. For people in all ages the Age Standardized YLL rate and Age Standardized AYLLs of stroke were higher for men (17.1 per 1 000; 11.1 years/person) than those for women (12.0 per 1 000; 10.0 years / person). YLL rate was larger for men than for women in all age groups before the age of 74, which was reversed in the age group of 75-84. YLL rate and Age Standardized YLL rate of hemorrhagic stroke were 7.7 per 1 000 and 5.9 per 1 000 respectively, which were less than those of ischemic stroke (8.6 per 1 000 and 6.6 per 1 000). In contrast, AYLLs and Age Standardized AYLLs of hemorrhagic stroke were higher than those of ischemic stroke. For people less than 59 the YLL rate of hemorrhagic stroke was higher than that of ischemic stroke. For people more than 60, the YLL rate of ischemic stroke was higher than that of hemorrhagic stroke. Conclusions The findings suggest that the disease burden of stroke-related deaths, which correlates to sex, subtype and age, is heavy in the rural areas in Liaoning province. It is necessary to carry out health education about stroke and take out effective prevention to reduce the burden of stroke-related death in rural areas.