Abstract: Objective To explore the situation of injury in elementary and middle school students in Yixing and analyze the working of the system of the students' injury monitoring and reporting, based on data of three years. Methods Students of 16 pilot schools in Yixing were recruited to conduct the study of daily injury network monitoring and the retrospective investigation. Results The injury incidence of students was 2.23% in retrospective investigation from September to November in 2015, and 247 cases were reported in the system. We found the injury incidence was lower than that in 2012. Falling/falling, injury due to animal, traffic accident and sharp instrument injury were the top four types. The injury incidence of the non-local students was slightly higher than that of the local students, but no statistical difference. The injury incidence of the males was significantly higher than that of the females. The results of daily injury network monitoring were close to that from retrospective investigation and difference of effect was decreased. Conclusions The efficiency and accuracy of daily injury monitoring network was enhanced in practice, and which could be combined with the retrospective investigation. In addition to the monitoring and reporting of injury, multi-sectors collaboration should be strengthened to explore the more effective measures.