Abstract: Tuberculosis is one of serious infectious diseases endangering life and health to the residents. The epidemic situation of tuberculosis is quite serious and China is one of the highest disease burden country worldwide. China has realized the commitment of tuberculosis control phased target to the international society on schedule. The mortality of TB obviously declined. The epidemic characteristics of tuberculosis in China is high infection rate, high prevalence, high drug resistance rate, and low detection rate, low cognitive rate, low dose rate, and the prevalence of falling slowly. The tuberculosis prevention and control situation is grim in China. In order to realize the 13th Five-Year Plan National Tuberculosis Control Program,we must be in accordance with the law and science to advance tuberculosis prevention and control strategy:The tuberculosis control work as an important content of construction in people's livelihood and in the plan for national economic and social development, as one of the government's target management evaluation content;To strengthen the information construction of tuberculosis control;Promoting tuberculosis service system including professional organizations of tuberculosis control, tuberculosis designated hospitals and community health center. Infectious tuberculosis patients should be hospitalization;Carrying out the care, monitoring, prevention and health education to the tuberculosis risk population;Extensively conducting propaganda education about the severity and harmfulness of tuberculosis and leave no one behind.