柳州市男男性行为队列人群HIV感染影响因素分析

刘雪梅; 黎明强; 韦东旭; 范引光; 蒋志宇; 冯献湘

doi:10.16462/j.cnki.zhjbkz.2017.12.011

柳州市男男性行为队列人群HIV感染影响因素分析

doi: 10.16462/j.cnki.zhjbkz.2017.12.011

1. 柳州市疾病预防控制中心性病艾滋病防治科, 广西柳州 545007;
2. 安徽医科大学公共卫生学院流行病与卫生统计学系, 安徽合肥 230032

基金项目:

2014年广西科学研究与技术开发计划（桂科攻14124003-1）；柳州市科学研究与技术开发计划（2014J030403）；2017年广西医药卫生自筹经费计划课题（Z20170957）

详细信息

作者简介:
刘雪梅(1980-),女,山东菏泽人,主管医师,硕士。主要研究方向:艾滋病综合防治。

中图分类号: R512.91
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出版历程
- 收稿日期: 2017-07-04
- 修回日期: 2017-10-16

Cohort study on the influential factors of HIV infection among men who have sex with men in Liuzhou City

1. AIDS Prevention and Control Institute, Liuzhou Center for Disease Prevention and Control, Liuzhou 545007, China;
2. Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei 230032, China

摘要

摘要: 目的利用队列人群数据探讨影响柳州市男男性行为人群（men who have sex with men，MSM）感染艾滋病的影响因素，为制定柳州市艾滋病预防控制策略和措施提供依据。方法 2014年6月在柳州市区采用雪球抽样方法招募MSM并建立队列，每半年随访一次，每次随访时进行问卷调查、采集静脉血进行艾滋病病毒（human immune deficiency virus，HIV）抗体检测。结果基线和三次随访共招募MSM 1 369人次，成功完成一次、二次、三次随访的人数分别为158例、126例、74例。随着随访次数增加，MSM队列人群对艾滋病相关知识的知晓率升高（χ_趋势²=7.698，P=0.006）；最近一次肛交性行为（χ_趋势²=7.510，P=0.006）和商业同性肛交性行为（χ_趋势²=5.005，P=0.025）中安全套使用情况均有上升的趋势。多因素Cox回归分析显示：艾滋病相关知识得分较高（OR=0.119，95%CI：0.021~0.686，P=0.017）及最近6个月未使用过毒品（OR=0.036，95%CI：0.006~0.212，P<0.001）者，其感染艾滋病的风险低。结论应进一步加强MSM人群艾滋病知识宣传，提高艾滋病相关知识知晓率和安全套使用频率，降低毒品使用，以遏制艾滋病在该人群的蔓延。
- 艾滋病 /
- 同性恋,男性 /
- 队列研究 /
- 随访研究
Abstract: Objective To understand the prevalence and influential factors of human immune deficiency virus(HIV)infection among men who have sex with men(MSM) in Liuzhou City, so as to provide the evidence for HIV prevention and control. Methods Snowball sampling method was used to set up MSM cohort in the urban area of Liuzhou from June 2014, and they were followed up each six months. Blood samples were taken from these MSM to detect antibodies of HIV. Results Baseline and three followers were recruited for 1 369 MSM. We successively completed the first follow-up (158 cases), the second follow-up (126 cases), and the third follow-up (74 cases). MSMs' knowledge of HIV/AIDS increaseed with the rise as the number of follow-up(χ²=7.698,P=0.006).Condom usage in the latest commercial anal sex (χ²=7.510,P=0.006) and anal same-sex sexual behavior (χ²=5.005,P=0.025) were in rising trend. Multifactorial Cox regression analysis showed that higher scores of HIV/AIDS related knowledge(OR=0.119,95% CI:0.021-0.686,P=0.017)and less drug use in the last 6 months (OR=0.036,95% CI:0.006-0.212,P<0.001), the risk of HIV infections was lower. Conclusions It is important to strengthen AIDS knowledge propaganda among MSM, raise the rate of AIDS related knowledge and the frequency of using comdom, reduce the drug use in order to curb the spread of AIDS in the MSM.
- AIDS /
- Men who have sex with men /
- Cohort study /
- Follow-up study