静脉注射吸毒人群HIV和HCV感染现状及影响因素的Meta分析

郑尔达; 高良敏; 彭霞; 谢天胜; 刘红艳; 孙悦琪; 黄津; 李洪

doi:10.16462/j.cnki.zhjbkz.2017.12.020

静脉注射吸毒人群HIV和HCV感染现状及影响因素的Meta分析

doi: 10.16462/j.cnki.zhjbkz.2017.12.020

郑尔达¹,
高良敏²,
彭霞¹,
谢天胜³,
刘红艳⁴,
孙悦琪⁴,
黄津⁴,
李洪^5, ,

1. 云南省疾病预防控制中心疫情监测/突发公共卫生事件处置中心, 云南昆明 650022;
2. 清华大学社会科学院社会学系, 北京 100008;
3. 浙江大学医学院附属第一医院传染病诊治国家重点实验室, 浙江杭州 310031;
4. 昆明医科大学公共卫生学院流行病与卫生统计系, 云南昆明 650500;
5. 云南省疾病预防控制中心科研教育服务部, 云南昆明 650022

基金项目:

“十二五”国家科技重大专项（2013ZX10004-906）

详细信息

作者简介:
郑尔达(1990-),男,云南昆明人,医师,硕士。主要研究方向:传染病流行病学。

中图分类号: R183;R181
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- 被引次数: 0
出版历程
- 收稿日期: 2017-06-28
- 修回日期: 2017-09-05

HIV and HCV infection situation and associated risk factors among injecting drug users: a Meta-analysis

1. Center for Epidemic Surveillance/Public Health Emergency Preparedness and Response, Yunnan Center for Disease Control and Prevention, Kunming 650022, China;
2. Department of Sociology, School of Social Science, Tsinghua University, Beijing 100008, China;
3. National Key Laboratory for Infectious Disease Diagnosis and Treatment, the First Affiliated Hospital of Medical School of Zhejiang University, Hangzhou 310031, China;
4. Department of Epidemiology and Health Statistics, School of Public Health, Kunming Medical University, Kunming 650500, China;
5. Department of Science Research and Education, Yunnan Center for Disease Control and Prevention, Kunming 650022, China

摘要

摘要: 目的了解中国内地静脉注射吸毒人群（injecting drug users，IDUs）中人类免疫缺陷病毒（human immunodeficiency virus，HIV）和丙型肝炎病毒（hepatitis C virus，HCV）感染状况及相关影响因素。方法通过相应检索策略收集2000-2015年期间针对该人群的HIV和HCV感染状况的文献，提取数据建立数据库后进行Meta分析。结果中国内地IDUs中HIV感染率为7.00%（95%CI：6.10%~8.00%），HCV感染率为67.10%（95%CI：61.00%~73.20%）。亚组分析显示，不同地区、不同人群和不同时间段HIV和HCV感染率不同；单因素Meta回归分析显示HCV感染率是HIV感染率的主要影响因素，高HCV感染率组HIV感染率高于低HCV感染率组。结论 2000-2015年中国内地IDUs HIV和HCV感染率较高，HIV感染率与HCV感染率关系密切，在IDUs中可用HCV感染率的高低来评估该人群中HIV的感染和流行风险。
- 人免疫缺陷病毒 /
- 肝炎病毒属 /
- Meta分析
Abstract: Objective To obtain the infection prevalence of human immunodeficiency virus(HIV)and hepatitis C virus(HCV) among Chinese injecting drug users (IDUs), and to estimate the associated risk factors of HIV/HCV(hepatitis C virus) infection. Methods Literatures on HIV and HCV infection among Chinese IDUs were collected with search strategies, data were abstracted to create the database and the meta-analysis were conducted. Results Prevalence of HIV among IDUs was 7.00% (95% CI:6.10%-8.00%), and the prevalence of HCV was 67.10% (95% CI:61.00%-73.20%). Subgroup analysis indicated that both of HIV and HCV prevalence were different among different groups of regions, types of population and periods. Single factor meta-regression indicated HCV infection was the major associated factors of HIV prevalence, and HIV prevalence in high HCV infection group was higher than it in low HCV infection group. Conclusions The prevalence of HIV and HCV were high among Chinese IDUs, and HIV prevalence was closely related to HCV prevalence. HCV prevalence could be used as a predictor of HIV prevalence among IDUs.
- Human immunodeficiency viruses /
- Hepacivirus /
- Meta-analysis