Abstract: Objective To analyze the epidemic trend and characteristics of scrub typhus in Fuzhou from 2011 to 2015, and to provide scientific basis for prevention and control of scrub typhus. Methods Descriptive epidemiological method was conducted to analyze the data of scrub typhus in Fuzhou from 2011 to 2015. Results A total of 677 scrub typhus cases were reported in Fuzhou from 2011 to 2015. The annual average incidence of scrub typhus was 3.42/100 000. The incidence showed an upward trend ((口恶)_trend²=630.823, P<0.001), and the annual average growth rate was 102.69%. The number of cases (accounted for 86.71%) and the annual average incidence of scrub typhus (40.26/100 000) in Nanfeng County were the highest in the counties of Fuzhou. The incidences of scrub typhus in Nanfeng County ((口恶)_trend²=571.513, P<0.001), Yihuang County ((口恶)_trend²=37.584, P<0.001) and Lichuan County ((口恶)_trend²=6.969,P=0.008) were on the rise. The incidence of scrub typhus was obviously seasonal, mainly from June to December (accounted for 98.23%), with the most cases (accounted for 56.13%) occurred in November and December. In all reported cases, male-female ratio was 1:1.21, 76.81% of them were between 40 and 69 years old, 51.11% of them were aged 50 years old and above, 94.68% of them were farmers. Conclusions The incidence of scrub typhus increased in Fuzhou in the past five years, with obvious seasonality. The epidemic situation of scrub typhus in Nanfeng County was fairly serious. The famers, women, middle-aged and elderly people were at high risk. Effective measures should be focused on the high-risk areas and key populations to control the scrub typhus epidemic.