云南省德宏州2017年婚检人群HIV感染率及影响因素分析

龚渝蓉; 乔世杰; 杨世江; 杨跃诚; 唐仁海; 曹艳芬; 高洁; 李林; 叶润华; 王继宝; 姚仕堂; 丁盈盈; 何纳; 段松

doi:10.16462/j.cnki.zhjbkz.2019.01.024

云南省德宏州2017年婚检人群HIV感染率及影响因素分析

doi: 10.16462/j.cnki.zhjbkz.2019.01.024

1.
678400 芒市, 云南省德宏傣族景颇族自治州疾病预防控制中心
2.
200032 上海, 复旦大学公共卫生学院流行病学教研室, 公共卫生安全教育部重点实验室

基金项目:

国家自然科学基金项目 81773485

国家重点地区艾滋病防治项目；国家科技重大专项 2013zx10004-906

详细信息

通讯作者:
段松, E-mail: dhduansong@sina.com.cn

何纳, E-mail: nhe@shmu.edu.cn

中图分类号: R181.2
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- 文章访问数: 226
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出版历程
- 收稿日期: 2018-08-17
- 修回日期: 2018-10-13
- 刊出日期: 2019-01-10

HIV prevalence and risk factors among premarital couples in Dehong Prefecture of Yunnan Province, 2017

1.
Dehong Prefecture Center for Disease Control and Prevention, Mangshi 678400, China
2.
Department of Epidemiology, School of Public Health, Fudan University; Key Laboratory for Public Health Safety of Ministry of Education, Shanghai 200032, China

Funds:

National Natural Science Foundation of China 81773485

National AIDS Control Projects in Key Regions; National Science and Technology Major Project of China 2013zx10004-906

More Information

Corresponding author: HE Na, E-mail: nhe@shmu.edu.cn; DUAN Song, E-mail: dhduansong@sina.com.cn

摘要

摘要: 目的了解2017年德宏州进行婚前医学检查人群中的（human immunodeficiency virus，HIV）感染状况并分析其影响因素。方法整理2017年德宏州的婚检人群数据，描述分析其人口学特征，并使用单因素和多因素Logistic回归分析相应的影响因素。结果 2017年德宏州共有21 875例婚检者参与HIV检测，有98人确证为HIV抗体阳性，HIV感染率为0.45%，男性感染率为0.47%（52/10 955），女性感染率为0.42%（46/10 920）。98例感染者中有20名感染者为首次新报告阳性，感染途径以性传播感染为主，占81.63%（80/98）。Logistic多因素回归分析显示：年龄、民族、是否吸毒是婚检人群HIV感染的影响因素。相对于25岁以下人群，31~、41~岁年龄组人群HIV感染危险性增加（OR=3.78，95%CI：1.81~7.89，P<0.001；OR=3.95，95%CI：1.72~9.08，P=0.001）；傣族、景颇族的HIV感染危险性高于汉族（OR=1.86，95%CI：1.06~3.29，P=0.031；OR=3.25，95%CI：1.81~5.84，P<0.001）。吸毒人群的HIV感染危险性远高于不吸毒人群（OR=926.76，95%CI：271.65~3161.71，P<0.001）。结论年龄、民族、是否吸毒为婚检人群HIV感染的影响因素，需要对危险因素采取针对性措施。HIV感染途径以性传播感染为主，通过婚检可以有效发现并控制HIV传播。
- 婚检人群 /
- HIV感染 /
- 影响因素
Abstract: Objective To understand the prevalence of HIV infection and its influencing factors in the premarital physical examination population in Dehong Prefecture, Yunnan Province, 2017. Methods The data of people receiving premarital medical examination was collected, the demographic characteristics was described and the related factors was analyzed by Logistic regression. Results There were 21 875 participants receiving premarital medical examination in Dehong. 98(0.45%) participants were confirmed positive for HIV and male infection rate was 0.47% (52/10 955) and female was 0.42% (46/10 920). Among the 98 patients, 20 patients were infected in the first time, and main route was sexual transmission accounting for 81.63% (80/98). Logistic multivariate regression analysis showed that age, ethnicity and drug use were the influencing factors for premarital couples infecting HIV. The risk of HIV infection in 31-40 and 41-50 years old group was higher than the people under 25 years old group(OR=3.78, 95% CI: 1.81-7.89, P<0.001;OR=3.95, 95% CI: 1.72-9.08, P=0.001). The infection risk of Dai and Jingpo ethnic group was higher than that of the Han ethnic(OR=1.86, 95% CI: 1.06-3.29, P=0.031;OR=3.25, 95% CI: 1.81-5.84, P<0.001). The risk of infection among drug users was much higher than non-drug users (OR=926.76, 95% CI: 271.65-3 161.71, P<0.001). Conclusion Age, ethnicity, and drug use are influencing factors of HIV infection among premarital couples. Targeted measures need to be taken against risk factors. HIV infection is mainly transmitted by sexual transmission. It can be effectively detected and controlled through premarital medical examination.
- Premarital couples /
- HIV infection /
- influencing factor

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表 1 2017年德宏州婚检人群HIV感染因素分析

Table 1. Risk Factors of HIV Infection Among Premarital Couples in Dehong Prefecture, 2017

特征(n=21 875)	人数[n(%)]	阳性[n(%)]	单因素Logistic回归		多因素Logistic回归
特征(n=21 875)	人数[n(%)]	阳性[n(%)]	OR(95%CI)值	P值	OR(95%CI)值	P值
年龄(岁)
0~	6 080(27.79)	10(0.16)	1.00		1.00
26~	728(32.59)	19(0.27)	1.62(0.75~3.49)	0.216	1.87(0.85~4.11)	0.120
31~	5 497(25.13)	41(0.75)	4.56(2.28~9.11)	<0.001	3.78(1.81~7.89)	<0.001
41~	2 207(10.09)	25(1.13)	6.96(3.34~14.50)	<0.001	3.95(1.72~9.08)	0.001
≥51	963(4.40)	3(0.31)	1.90(0.52~6.91)	0.331	1.52(0.40~5.80)	0.536
性别
男	10 955(50.08)	52(0.47)	1.00		1.00
女	10 920(49.92)	46(0.42)	0.89(0.60~1.32)	0.554	1.44(0.91~2.27)	0.119
民族
汉族	10 141(46.36)	26(0.26)	1.00		1.00
傣族	6 434(29.41)	31(0.48)	1.88(1.12~3.18)	0.017	1.86(1.06~3.29)	0.031
景颇族	3 016(13.79)	31(1.03)	4.04(2.40~6.82)	<0.001	3.25(1.81~5.84)	<0.001
其他^a	2 284(10.44)	10(0.44)	1.71(0.82~3.55)	0.150	1.21(0.52~2.81)	0.663
职业
农民	16 404(74.99)	91(0.55)	1.00		1.00
非农民^b	5 471(25.01)	7(0.13)	0.23(0.11~0.50)	<0.001	0.51(0.21~1.29)	0.157
文化程度
小学及以下	7 498(34.28)	54(0.72)	1.00		1.00
初中	9 066(41.44)	38(0.42)	0.58(0.38~0.88)	0.010	0.95(0.58~1.56)	0.844
高中及以上	5 311(24.28)	6(0.11)	0.16(0.07~0.36)	<0.001	0.41(0.15~1.16)	0.094
是否吸毒
否	21 853(99.90)	80(0.37)	1.00		1.00
是	22(0.10)	18(81.82)	1 224.73(405.47~3 699.33)	<0.001	926.76(271.65~3 161.71)	<0.001
婚前性行为
否	1 808(8.27)	13(0.72)	1.00		1.00
是	20 067(91.73)	85(0.42)	0.59(0.33~1.06)	0.075	0.58(0.30~1.10)	0.096
国籍
中国籍	20 289(92.75)	93(0.46)	1.00		1.00
缅籍	1 586(7.25)	5(0.32)	0.69(0.28~1.69)	0.414	0.50(0.19~1.30)	0.155
注：^a其他少数民族包括傈僳族、阿昌族、德昂族等；^b非农民包括商业服务业、干部职员、医务人员等职业。

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特征(n=21 875)	人数[n(%)]	阳性[n(%)]	单因素Logistic回归		多因素Logistic回归
特征(n=21 875)	人数[n(%)]	阳性[n(%)]	OR(95%CI)值	P值	OR(95%CI)值	P值
年龄(岁)
0~	6 080(27.79)	10(0.16)	1.00		1.00
26~	728(32.59)	19(0.27)	1.62(0.75~3.49)	0.216	1.87(0.85~4.11)	0.120
31~	5 497(25.13)	41(0.75)	4.56(2.28~9.11)	<0.001	3.78(1.81~7.89)	<0.001
41~	2 207(10.09)	25(1.13)	6.96(3.34~14.50)	<0.001	3.95(1.72~9.08)	0.001
≥51	963(4.40)	3(0.31)	1.90(0.52~6.91)	0.331	1.52(0.40~5.80)	0.536
性别
男	10 955(50.08)	52(0.47)	1.00		1.00
女	10 920(49.92)	46(0.42)	0.89(0.60~1.32)	0.554	1.44(0.91~2.27)	0.119
民族
汉族	10 141(46.36)	26(0.26)	1.00		1.00
傣族	6 434(29.41)	31(0.48)	1.88(1.12~3.18)	0.017	1.86(1.06~3.29)	0.031
景颇族	3 016(13.79)	31(1.03)	4.04(2.40~6.82)	<0.001	3.25(1.81~5.84)	<0.001
其他^a	2 284(10.44)	10(0.44)	1.71(0.82~3.55)	0.150	1.21(0.52~2.81)	0.663
职业
农民	16 404(74.99)	91(0.55)	1.00		1.00
非农民^b	5 471(25.01)	7(0.13)	0.23(0.11~0.50)	<0.001	0.51(0.21~1.29)	0.157
文化程度
小学及以下	7 498(34.28)	54(0.72)	1.00		1.00
初中	9 066(41.44)	38(0.42)	0.58(0.38~0.88)	0.010	0.95(0.58~1.56)	0.844
高中及以上	5 311(24.28)	6(0.11)	0.16(0.07~0.36)	<0.001	0.41(0.15~1.16)	0.094
是否吸毒
否	21 853(99.90)	80(0.37)	1.00		1.00
是	22(0.10)	18(81.82)	1 224.73(405.47~3 699.33)	<0.001	926.76(271.65~3 161.71)	<0.001
婚前性行为
否	1 808(8.27)	13(0.72)	1.00		1.00
是	20 067(91.73)	85(0.42)	0.59(0.33~1.06)	0.075	0.58(0.30~1.10)	0.096
国籍
中国籍	20 289(92.75)	93(0.46)	1.00		1.00
缅籍	1 586(7.25)	5(0.32)	0.69(0.28~1.69)	0.414	0.50(0.19~1.30)	0.155
注：^a其他少数民族包括傈僳族、阿昌族、德昂族等；^b非农民包括商业服务业、干部职员、医务人员等职业。

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云南省德宏州2017年婚检人群HIV感染率及影响因素分析

doi: 10.16462/j.cnki.zhjbkz.2019.01.024

通讯作者:
段松, E-mail: dhduansong@sina.com.cn

何纳, E-mail: nhe@shmu.edu.cn

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HIV prevalence and risk factors among premarital couples in Dehong Prefecture of Yunnan Province, 2017

Corresponding author: HE Na, E-mail: nhe@shmu.edu.cn; DUAN Song, E-mail: dhduansong@sina.com.cn

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云南省德宏州2017年婚检人群HIV感染率及影响因素分析

doi: 10.16462/j.cnki.zhjbkz.2019.01.024

通讯作者: 段松, E-mail: dhduansong@sina.com.cn 何纳, E-mail: nhe@shmu.edu.cn

计量

出版历程

HIV prevalence and risk factors among premarital couples in Dehong Prefecture of Yunnan Province, 2017

Corresponding author: HE Na, E-mail: nhe@shmu.edu.cn; DUAN Song, E-mail: dhduansong@sina.com.cn

计量

出版历程

目录

通讯作者:
段松, E-mail: dhduansong@sina.com.cn

何纳, E-mail: nhe@shmu.edu.cn