Quality of life and its influencing factors of hepatitis B positive in pregnant women in Jianyang
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摘要:
目的 分析简阳市乙型肝炎(以下简称乙肝)阳性孕妇生命质量及其影响因素。 方法 随机选取2018年1月~4月简阳市妇幼保健院就诊的80名乙肝阳性孕妇作为病例组,选择同期就诊的323名正常孕妇作为对照组,使用简明健康调查量表SF-36进行面对面调查,运用t检验、方差分析、多元线性回归进行统计分析。 结果 病例组生理功能(PF)、生理职能(RP)得分低于对照组,总体健康(GH)得分高于对照组,差异有统计学意义。分析病例组生命质量的影响因素发现,早孕反应越严重,生命质量评分越低。 结论 简阳市乙肝阳性孕妇生理功能及生理职能较正常孕妇差,应采取综合性措施,提高其生命质量。 Abstract:Objective To evaluate the quality of life in pregnant women with hepatitis B positive and to explore its influencing factors. Methods Eighty pregnant women with positive hepatitis B were randomly selected from Jan. to Apr. 2018 in Jianyang Maternal and Child Health Hospital as the case group, and 323 normal pregnant women were selected as the control group. A face-to-face survey was conducted using the Concise Health Survey Scale SF-36. t test, ANOVA and multiple linear regression were used for statistical analysis. Results The scores of PF and RP in the case group were lower than those in the control group, and the scores of GH in the case group were higher than those in the control group. Analysis of the factors affecting the quality of life of the case group found that the more severe the early pregnancy reaction, the lower the quality of life score. Conclusions The PF and RP of pregnant women with hepatitis B positive in Jianyang City are worse than those of normal pregnant women. Comprehensive measures should be taken to improve their quality of life. -
Key words:
- Hepatitis B /
- Pregnant women /
- Quality of life
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表 1 SF-36量表各维度初得分计算
Table 1. Calculation of initial scores of all dimensions in SF-36 scale
维度 初得分的计算公式 初得分的理论最高值与最低值 生理功能(PF) 3a+3b+3c+3d+3e+3f+3g+3h+3i+3j 10, 30 生理职能(RP) 4a+4b+4c+4d 4, 8 身体疼痛(BP) 7+8 2, 12 总体健康(GH) 1+2+11a+11b+11c+11d 6, 30 活力(VT) 9a+9e+9g+9i 4, 24 社会功能(SF) 6+10 2, 10 情感职能(RE) 5a+5b+5c 3, 6 精神健康(MH) 9b+9c+9d+9f+9h 5, 30 表 2 调查对象一般人口学特征
Table 2. General demographic characteristics of the respondents
条目 病例组(n=80) 对照组(n=323) χ2值 P值 年龄(岁) 3.892 0.421 <20 1 10 20~ 20 111 25~ 39 129 30~ 16 59 ≥35 4 14 民族 1.251a 0.263 汉族 80 318 其他 0 5 职业 10.403a 0.077 农民 0 4 工人 1 3 服务业 0 20 经商 1 8 家务或待业 68 242 教师/公务员/职员 5 35 其他 5 11 户居住地 4.096a 0.215 城市 0 8 城镇 33 157 城郊 1 2 农村 46 156 婚姻状况 11.436a 0.014 未婚 0 23 同居 0 3 初婚 73 280 再婚 6 17 离异/丧偶 1 0 文化程度 2.724a 0.414 小学 1 5 初中 41 139 高中或中专 23 92 大专及以上 15 87 家庭人均月收入(元) 4.810 0.182 ≤3000 4 14 3001~ 47 168 5001~ 28 116 ≥10000 1 25 医保类型 6.205a 0.167 城镇职工医疗保险 9 63 城镇居民医疗保险 28 110 商业医疗保险 1 0 新农合 42 150 分娩次数 4.324a 0.232 0 38 134 1 39 177 2 2 12 ≥3 1 0 早孕反应 5.362 0.146 无 5 34 轻度 40 180 中度 29 99 重度 6 10 孕期(周) 0.342 0.833 孕早期(≤27) 38 158 孕中期(28~) 36 135 孕晚期(≥38) 6 29 产前检查 19.402a <0.001 从未做过 2 15 不定期 2 64 遵医嘱定期做 76 242 异常时做 0 1 与配偶感情 2.295 0.317 很好 49 177 较好 30 132 一般 1 14 家人有无乙肝病毒感染者 34.232 <0.001 有 23 20 无 57 303 注:a采用Fisher确切概率法。 表 3 病例组与对照组生命质量得分比较
Table 3. Comparison of quality of life scores between the case group and the control group
维度 x±s t值 P值 病例组 对照组 PF 87.81±11.162 91.50±9.399 -3.023 0.003 RP 50.00±41.147 65.25±39.080 -3.091 0.002 BP 87.96±14.868 87.96±14.760 -0.001 0.999 GH 45.21±4.693 42.52±4.829 4.486 <0.001 VT 55.13±6.607 55.56±7.569 -0.468 0.640 SF 62.50±5.967 62.62±7.000 -0.137 0.891 RE 74.58±37.967 72.45±37.627 0.454 0.650 MH 61.60±6.255 61.80±6.255 -0.251 0.802 总分 524.79±87.864 539.64±81.560 -1.436 0.152 表 4 病例组SF-36维度得分单因素方差分析(x±s)
Table 4. One-way ANOVA of SF-36 dimension scores in the case group (x±s)
条目 PF RP GH 总分 年龄(岁) <24 91.19±8.20 58.33±38.19 44.64±3.98 535.17±83.06 25~ 86.67±13.25 51.92±43.45 44.34±4.63 518.45±101.17 30~ 86.25±9.75 37.50±38.73 47.40±5.46 525.46±71.13 ≥35 87.50±5.00 37.50±43.30 47.92±2.41 529.39±32.37 户居住地 城市 89.39±8.17 48.48±40.96 45.71±4.71 534.97±80.04 城郊及农村 86.70±12.82 51.06±41.69 44.86±4.70 517.64±93.14 文化程度 初中及以下 87.14±13.49 44.05±40.89 44.44±4.38 515.81±91.91 高中或中专 87.39±8.24 48.91±44.26 46.56±5.13 523.44±89.56 大专及以上 90.33±7.43 68.33±33.36 45.28±4.69 551.99±71.99 家庭人均月收入(元) ≤3 000 78.75±11.09 31.25±37.50 43.75±5.38 508.40±83.19 3 001~ 87.02±12.50 47.34±43.06 45.57±4.55 517.49±91.84 ≥5 000 90.34±7.90 56.90±38.32 44.83±4.94 538.87±82.76 早孕反应 无及轻度 91.00±8.30 63.33±40.45 44.17±4.39 559.01±68.77 中度 85.69±13.14 37.93±36.36 47.41±4.51 497.44±87.62 重度 74.17±7.36 8.33±20.41 42.36±4.10 400.29±62.28 夫妻感情 很好 88.67±12.36 52.04±40.77 45.32±5.15 526.18±88.89 较好及一般 86.45±8.96 46.77±42.20 45.03±3.94 522.58±87.64 表 5 调查对象生命质量影响因素的多元线性回归分析
Table 5. Multiple linear regression analysis of factors influencing the quality of life of the respondents
评分 变量 β 标准误差 标准化系数 t值 P值 PF 早孕反应 -3.138 0.688 -0.221 -4.564 <0.001 是否感染乙肝病毒 3.103 1.198 0.126 2.590 0.010 RP 早孕反应 -12.581 2.780 -0.219 -4.525 <0.001 是否感染乙肝病毒 12.897 4.845 0.129 2.662 0.008 GH 早孕反应 0.953 0.343 0.135 2.777 0.006 是否感染乙肝病毒 -2.512 0.598 -0.204 -4.100 <0.001 -
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