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摘要:
目的 掌握江西省2011-2017年人间布鲁氏菌病疫情特征，为今后的防控工作提供参考依据。 方法 结合省内监测资料，对江西省2011-2017年在传染病报告信息管理系统中报告的布病病例进行分析。 结果 2011-2017年江西省共报告布病239例，年均发病率为0.08/10万。病例和聚集性疫情集中在南昌市地区(48例/4起)。地市分布由2011年的1个地级市至2016年全覆盖，涉及县(区)数由2011年的1个增长至2017年的68个，扩增趋势明显(χ趋势2=94.31，P < 0.001)。男女性别比为3.12：1(181：58)。年龄集中在40~65岁年龄组。职业分布以农牧民为主，占59.83%(143/239)。5~9月为发病高峰(5~6月大高峰和9月小高峰)。2012-2017年共采集血清样本7 160份，阳性率1.33%(95/7 160)。2013-2017年从193例病例血液中分离出布病菌株62株，羊Ⅰ 4株，羊Ⅲ 54株，猪Ⅰ 4株。 结论 江西省人间布病疫情呈上升势态，流行范围在不断扩大。有关部门加强监管力度、扩充监测内容可能为今后的布病防控重点。 Abstract:Objective To investigate the epidemic characteristics of human brucellosis in Jiangxi province from 2011 to 2017, thereby providing reference for future prevention and control work. Methods We analyzed the case information reported in the National Notifiable Infectious Diseases Reporting Information System of Jiangxi Province during 2011-2017 by combining with the monitoring data. Results A total of 239 cases were recorded over these six years, with an average incidence rate of 0.08/100 000. Most cases and agglomerations were concentrated in the Nanchang area (48 cases/4 cases), with the case distribution ranging from 1 in 2011 to all in 2016, and the number of counties(districts) involved had increased from 1 in 2011 to 68 in 2017, which increased rapidly year by year (χ2=94.31, P < 0.001). The gender ratio was 3.12:1(181:58). Most cases were concentrated in the 40-65 age group, while farmers and herdsmen were high-risk population, accounting for 59.83% (143/239). The incidence of brucellosis peaked from May to September (May peak and September peak). In 2012-2017, 7 160 blood samples were collected from risk population, with 95 being positive for Brucella (1.33%). From 2013 to 2017, 62 strains of the Brucella, 4 were Brucella melitensis type1, 54 were Brucella melitensis type3 and 4 were Brucella suis were isolated from 193 cases. Conclusions The human brucellosis was aggravated in Jiangxi province, with the expansion of regional scope. Therefore, more efforts should be focused on regulation to prevent and control brucellosis better. -
Key words:
- Human brucellosis /
- Epidemiologic /
- Surveillance
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图 1 江西省2011-2017年布病发病率(/10万)
Figure 1. Incidence of brucellosis in Jiangxi Province from 2011 to 2017(/100 000)
图 2 江西省2012-2017年布病发病数职业分布(%)
Figure 2. Vocational distribution of brucellosis incidence case in Jiangxi Province from 2011 to 2017(%)
图 3 江西省2011-2017年布病发病数月份分布
Figure 3. Month distribution of brucellosis incidence case in Jiangxi Province from 2011 to 2017
表 1 江西省2011-2017年布病疫情统计
Table 1. Statistics of brucellosis epidemics in Jiangxi Province from 2011 to 2017
年份 疫情起数 发病数 波及人数 涉及地区数 2012 1 3 9 1 2013 3 4 2 881 3 2014 2 4 53 2 2015 3 3 24 3 2016 1 6 20 1 合计 10 20 2 987 10 
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表 2 江西省2011-2017年布病发病数年龄分布
Table 2. Age distribution of brucellosis incidence case in Jiangxi Province from 2011 to 2017
年龄组(岁) 报告病例数(例) 构成比(%) 0~ 3 1.26 5~ 1 0.42 10~ 2 0.84 15~ 7 2.93 20~ 9 3.77 25~ 10 4.18 30~ 18 7.53 35~ 18 7.53 40~ 34 14.23 45~ 34 14.23 50~ 37 15.48 55~ 26 10.88 60~ 26 10.88 65~ 10 4.18 70~ 4 1.67 ≥75 0 0.00 合计 239 100
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表 3 江西省2012-2017年人间布病血清学监测结果
Table 3. Surveillance result of human brucellosis serology in Jiangxi Province from 2011 to 2017
年份 血清学检查人数 SAT检测阳性数 阳性率(%) 发病数 发病率(/10万) 2012 119 3 2.52 0 0.000 2013 815 6 0.74 0 0.000 2014 340 15 4.41 12 0.027 2015 1 818 32 1.76 8 0.018 2016 1 951 22 1.12 1 0.002 2017 2 117 17 0.80 1 0.002 合计 7 160 95 1.33 22
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表 4 江西省2013-2017年人间布病病原学监测结果
Table 4. Surveillance result of human brucellosis aetiology in Jiangxi Province from 2013 to 2017
年份 病原分离数(株) 羊种 猪Ⅰ 羊Ⅰ 羊Ⅲ 2013年 5 0 5 0 2014年 19 2 17 0 2015年 13 0 13 0 2016年 19 2 15 2 2017年 6 0 4 2 合计 62 4 54 4
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