甘肃省2004-2018年丙型肝炎流行特征

赵亚栋; 屠爱霞; 王晓蕊; 王斌

doi:10.16462/j.cnki.zhjbkz.2019.08.008

甘肃省2004-2018年丙型肝炎流行特征

doi: 10.16462/j.cnki.zhjbkz.2019.08.008

730000 兰州, 甘肃省疾病预防控制中心性病艾滋病防制所

基金项目:

甘肃省卫生行业科研计划项目 GSWSKY2018-36

详细信息

通讯作者:
赵亚栋. E-mail: zhaoydong99@163.com

中图分类号: R512.63
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出版历程
- 收稿日期: 2019-03-26
- 修回日期: 2019-06-17
- 刊出日期: 2019-08-10

Epidemiologic characteristics of hepatitis C in Gansu Province from 2004 to 2018

Section of AIDS/STD Control and Prevention, Gansu Provincial Center for Disease Control and Prevention, Lanzhou 730000, China

Funds:

Medical Research Management Project of Gansu Province GSWSKY2018-36

More Information

Corresponding author: ZHAO Ya-dong. E-mail: zhaoydong99@163.com

摘要

摘要: 目的分析甘肃省丙型病毒性肝炎流行特征及其变化趋势，为制定防制措施提供科学依据。方法收集2004-2018年甘肃省丙型肝炎报告病例资料，采用Excel 2010、SPSS 19.0及ArcGIS 10.5软件进行资料整理与统计分析。结果 2004-2018年甘肃省累计报告丙型肝炎病例数为102 802例，其中死亡42例，报告发病率从2004年的12.39/10万上升到2018年的33.92/10万（χ²=9 849.90，P < 0.001）。报告发病率随着年龄的增长呈上升趋势（χ²=26 784.53，P < 0.001），≥ 80岁年龄组报告发病率最高（94.09/10万），≥ 50岁年龄组报告发病率均超过50.00/10万。报告病例中农民所占比例逐年上升，2018年农民所占的构成比达67.31%。14个市（自治州）报告发病率均呈增长趋势，累计报告发病率排在前三位的市（自治州）是武威市（1 098.42/10万），张掖市（1 077.69/10万）和兰州市（692.55/10万）。结论甘肃省丙肝报告疫情仍呈上升趋势，应加强重点人群和地区疫情监测，加强健康教育，提高公众对丙肝的认识。
- 丙型肝炎 /
- 流行特征 /
- 甘肃
Abstract: Objective The aim is to provide scientific evidence for the strategy of prevention and control through analyzing the epidemic characteristics and change tendency of hepatitis C virus infection in Gansu Province. Methods Data of hepatitis C virus infection reported cases in Gansu Province from 2004 to 2018 were collected and analyzed by Excel 2010, SPSS 19.0 and ArcGIS 10.5 software. Results 102 802 hepatitis cases were reported including 42 death cases in Gansu Province from 2004 to 2018. The reported incidence increased from 12.39 per 100 000 in 2004 to 33.92 per 100 000 in 2018 (χ²=9 849.90, P < 0.001).The reported incidence of hepatitis C virus infection showed a rising trends with the aging of the patients (χ²=26 784.53, P < 0.001), and the highest reported incidence was the group of over 80 years(94.09 per 100 000), and exceed 50.00 per 100 000 from the each group of over 50 years. Moreover, the proportion of farmers of the reported cases increased year by year and the proportion of farmers was 67.31% in 2018.The reported incidence rates of 14 cities (autonomous prefecture) in Gansu Province showed an increasing trend. The cities (autonomous prefecture) with the highest reported incidence rates were Wuwei (1 098.42 per 100 000), Zhangye (1 077.69 per 100 000) and Lanzhou City (692.55 per 100 000). Conclusions The epidemic situation of hepatitis C virus infection in Gansu Province is still rising. It is necessary to strengthen the surveillance of key populations and areas, enhance health education, and raise public awareness of hepatitis C virus infection.
- Hepatitis C /
- Epidemiologic characteristic /
- Gansu

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图 1 2004-2018年甘肃省丙肝报告发病率趋势分布

Figure 1. The hepatitis C reported incidence in Gansu Province from 2004 to 2018

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图 2 2004-2018年甘肃省丙肝报告病例的年龄和性别分布

Figure 2. Age and sex distribution of reported cases of hepatitis C in Gansu Province from 2004 to 2018

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图 3 2004-2018年甘肃省丙肝报告病例的时间分布

Figure 3. Temporal distribution of hepatitis C reported cases in Gansu Province from 2004 to 2018

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图 4 2004、2009、2014和2018年甘肃省丙肝报告发病率(/10万)地区分布

Figure 4. Regional distribution of hepatitis C reported incidence(per 100 000)in Gansu Province in 2004, 2009, 2014 and 2018

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表 1 2004-2018年甘肃省丙肝报告发病及死亡情况

Table 1. The hepatitis C reported incidence and death in Gansu Province from 2004 to 2018

年份(年)	人口数(万)	病例数(例)	发病率(/10万) (95% CI)	死亡数(例)	病死率(%)
2004	2 613.88	3 238	12.39(9.99~14.79)	2	0.06
2005	2 578.47	3 239	12.56(10.16~14.96)	1	0.03
2006	2 594.00	3 479	13.41(11.01~15.81)	4	0.11
2007	2 606.01	4 882	18.73(16.33~21.13)	6	0.12
2008	2 617.01	5 801	22.17(19.77~24.57)	4	0.07
2009	2 628.13	6 970	26.52(24.12~28.92)	1	0.01
2010	2 635.46	7 871	29.87(27.47~32.27)	6	0.08
2011	2 557.52	9 081	35.51(33.11~37.91)	6	0.07
2012	2 564.19	9 452	36.86(34.46~39.26)	5	0.05
2013	2 577.55	7 820	30.34(27.94~32.74)	6	0.08
2014	2 582.18	7 391	28.62(26.22~31.02)	1	0.01
2015	2 590.78	7 916	30.55(28.15~32.95)	0	-
2016	2 599.55	8 020	30.85(28.45~33.25)	0	-
2017	2 610.00	8 735	33.47(31.07~35.87)	0	-
2018	2 625.71	8 907	33.92(31.52~36.32)	0	-

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表 2 2004-2018年甘肃省丙肝报告病例的职业分布

Table 2. The number of hepatitis C case of different career in Gansu Province from 2004 to 2018

职业	累计报告数(例)	构成比(%)
农民	49 357	48.01
离退休人员	14 497	14.10
家政、家务及待业	11 741	11.42
工人	7 578	7.37
公务人员及职员	5 607	5.45
不详	2 940	2.86
其它	2 897	2.82
学生	2 300	2.24
教师	1 622	1.58
商务人员	1 561	1.52
医务人员	737	0.72
散居儿童	695	0.68
民工	492	0.48
牧民	377	0.37
餐饮食品人员	181	0.18
幼托儿童	115	0.11
公共场所服务员	57	0.06
海员及长途驾驶员	34	0.03
保育员	14	0.01
总计	102 802	100.00

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