Current situation and influencing factors of abnormal glucose metabolism in junior middle school students in Yanqing District, Beiing
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摘要:
目的 了解北京市延庆区初中生糖代谢异常现状及其影响因素。 方法 采用分层整群随机抽样的方法在延庆区抽取4所初中的2 493名在校生进行问卷调查、体格检查和空腹毛细血管血糖筛查。 结果 糖尿病、空腹血糖受损、糖代谢异常患病率分别为2.5%、11.4%、13.9%。不同年龄、不同年级、不同地区、超重、肥胖、向心性肥胖、高血压的初中生糖代谢异常患病情况差异均有统计学意义(均有P < 0.05);多因素非条件Logistic回归模型分析显示,城区、向心性肥胖、高血压与中学生糖代谢异常的危险呈正相关;每天吃早餐与中学生患糖代谢异常的危险呈负相关。 结论 北京市延庆区初中生糖代谢异常患病率较高,城区、向心性肥胖、高血压和每天吃早饭是该地初中生糖代谢异常的影响因素。 Abstract:Objective To understand the current situation and influencing factors of abnormal glucose metabolism in junior middle school students in Yanqing District, Beijing. Methods With the mothod of stratified cluster random sampling, the questionnaire, physical examination and fasting capillary blood glucose were conducted in 2 493 students from 4 junior high schools. Results The prevalence of diabetes, impaired fasting glucose, and abnormal glucose metabolism were 2.5%, 11.4%, and 13.9%, respectively. The prevalence of abnormal glucose metabolism varied significantly among different ages, grades, regions, obesity, central obesity and hypertension (all P < 0.05); Unconditional multiple Logistic regression analysis showed that urban, centripetal obesity, and hypertension were positively associated with the risk of abnormal glucose metabolism in middle school students in Yanqing District; daily breakfast was negatively associated with the risk of abnormal glucose metabolism. Conclusion The prevalence of abnormal glucose metabolism is high among junior middle school students, urban, central obesity, high blood pressure and daily breakfast are influencing factors of abnormal glucose metabolism in Yanqing District of Beijing. -
表 1 不同特征初中生糖代谢异常患病情况比较
Table 1. Comparison of prevalence of abnormal glucose metabolism in junior high school students with different characteristics
特征 调查人数 糖代谢异常 糖耐量受损 糖尿病 人数[n(%)] χ2值 P值 人数(%) χ2值 P值 人数[n(%)] χ2值 P值 性别 90.185 0.003 3.898 0.053 0.299 0.603 男生 1 260 177(14.0) 144(11.4) 33(2.6) 女生 1 186 163(13.7) 136(11.5) 27(2.3) 年龄 23.424 <0.001 15.459 0.0011 0.377 0.016 12 595 114(19.2) 89(15.0) 25(4.2) 13 977 134(13.7) 116(11.9) 18(1.8) 14 554 64(11.6) 52(9.4) 12(2.2) 15 320 28(8.8) 23(7.2) 5(1.6) 年级 15.012 0.0011 0.420 0.005 8.235 0.016 初一 964 164(17.0) 130(13.5) 34(3.5) 初二 811 106(13.1) 94(11.6) 12(1.5) 初三 671 70(10.4) 56(8.3) 14(2.1) 地区 57.855 <0.001 42.217 <0.001 13.232 <0.001 城区 1 378 127(9.2) 107(7.8) 20(1.5) 郊区 1 068 213(19.9) 173(16.2) 40(3.7) 民族 0.292 0.668 0.728 0.484 0.300 0.628 汉族 2 248 315(14.0) 261(11.6) (542.4) 其他 198 25(12.6) 19(9.6) 6(3.0) 家族史 0.238 0.627 0.006 1.000 1.555 0.267 是 151 23(15.2) 17(11.3) 6(4.0) 否 2 295 317(13.8) 263(11.5) 54(2.4) 超重 12.032 0.001 6.289 0.014 6.738 0.011 是 766 134(17.5) 106(13.8) 28(3.7) 否 1 680 206(12.3) 174(10.4) 32(1.9) 肥胖 9.866 0.003 4.675 0.038 6.627 0.019 是 397 75(18.9) 58(14.6) 17(4.3) 否 2 049 265(12.9) 222(10.8) 43(2.1) 向心性肥胖 11.121 0.001 7.663 0.008 3.100 0.088 是 340 67(19.7) 54(15.9) 13(3.8) 否 2 106 273(13.0) 226(10.7) 47(2.2) 高血压 5.752 0.018 6.358 0.014 0.030 0.889 是 790 129(16.3) 109(13.8) (202.5) 否 1 656 211(12.7) 171(10.3) 40(2.4) 表 2 延庆区中学生糖代谢异常影响因素单因素Logistic回归分析
Table 2. Single factor Logistic regression analysis of influencing factors of abnormal glucose metabolism in middle school students in Yanqing District
因素 β sx Wals χ2值 P值 OR(95% CI)值 年龄(岁) 15 1.000 12 0.905 0.224 16.379 < 0.001 2.472(1.595~3.831) 13 0.505 0.219 5.346 0.021 1.658(1.080~2.544) 14 0.309 0.238 1.681 0.195 1.362(0.854~2.173) 年级 初一 1.000 初二 -0.310 0.135 5.281 0.022 0.733(0.563~0.955) 初三 -0.565 0.153 13.720 < 0.001 0.568(0.421~0.766) 地区 郊区 1.000 城区 0.898 0.121 55.433 < 0.001 2.454(1.937~3.108) 超重 否 1.000 是 0.196 0.156 1.580 0.209 1.216(0.896~1.651) 肥胖 否 1.000 是 0.450 0.144 9.740 0.002 1.568(1.182~2.080) 向心性肥胖 否 1.000 是 0.499 0.151 10.943 0.001 1.648(1.226~2.215) 高血压 否 1.000 是 0.290 0.121 5.725 0.017 1.337(1.054~1.695) 每天吃早餐 否 1.000 是 -0.404 0.158 6.542 0.011 0.668(0.490~0.910) 每周中重度体育锻炼次数(次) 6~ 1.000 ≤1 0.377 0.239 2.489 0.115 0.457(0.913~2.327) 2~ 0.615 0.174 12.463 < 0.001 1.849(1.315~2.602) 4~ 0.474 0.180 6.913 0.009 1.607(1.128~2.288) -
[1] 黎君君, 吴曙粤, 刘春斌. 儿童糖尿病的流行病学研究近况[J]. 内科, 2015, 10(3): 389-392. DOI: 10.16121/j.cnki.cn45-1347/r.2015.03.44.Li JJ, Wu SY, Liu CB. Recent epidemiological research on childhood diabetes mellitus[J]. Internal Medicine of China, 2015, 10(3): 389-392. DOI: 10.16121/j.cnki.cn45-1347/r.2015.03.44. [2] Chen CM, Lou MF, Gau BS. Prevalence of impaired fasting glucose and analysis of related factors in Taiwanese adolescents[J]. Pediatr Diabetes, 2014, 15(3): 220-228. DOI: 10.1111/pedi.12081. [3] 学生健康检查技术规范[S]GB/T26343-2010, . GB/T 26343-2010, student health inspection technical specification[S]. [4] 学龄儿童青少年超重与肥胖筛查[S]WS/T586-2018, . WS/T586-2018, screening for overweight and obesity among school-age children and adolescents[S]. [5] Ji CY, Sung RY, Ma GS, et al. Waist circumference distribution of Chinese school-age children and adolescents[J]. Biomed Environ Sci, 2010, 23(1): 12-20. DOI: 10.1016/S0895-3988(10)60026-8. [6] 顾萍, 马爱国, 张芳, 等. 成人腰围和BMI诊断脂代谢异常最佳界值点分析[J]. 青岛大学医学院学报, 2011, 47(4): 290-292. DOI: 10.11712/qdyxy201104004.Gu P, Ma AG, Zhang F, et al. Analysis of optimal boundary point of abnormal lipid metabolism in adult waist circumference and BMI[J]. Acta Academiae Medicinae Qingdao Universitatis, 2011, 47(4): 290-292. DOI: 10.11712/qdyxy201104004. [7] 王文绢, 王克安, 陈春明, 等. 北京地区儿童青少年体重指数与血压关系的研究[J]. 中华流行病学杂志, 2004, 25(2): 109-112. DOI: 10.3760/j.issn:0254-6450.2004.02.005.Wang WJ, Wang KA, Chen CM, et al. Study on the relationship between body mass index and blood pressure in children and adolescents in Beijing[J]. Chin J Epidemiol, 2004, 25(2): 109-112. DOI: 10.3760/j.issn:0254-6450.2004.02.005. [8] 钱荣立. 关于糖尿病的新诊断标准与分型[J]. 中国糖尿病杂志, 2000, 8(1): 5-6. DOI: 10.3321/j.issn:1006-6187.2000.01.001.Qian RL. New diagnostic criteria and classification of diabetes mellitus[J]. Chin J Diabetes, 2000, 8(1): 5-6. DOI: 10.3321/j.issn:1006-6187.2000.01.001. [9] 曹冰燕, 米杰, 巩纯秀, 等. 北京市19593名儿童青少年糖尿病患病现况调查[J]. 中华流行病学杂志, 2007, 28(7): 631-634. DOI: 10.3760/j.issn:0254-6450.2007.07.002.Cao BY, Mi J, Gong CX, et al. Investigation on the prevalence of diabetes in 19593 children and adolescents in Beijing[J]. Chin J Epidemiol, 2007, 28(7): 631-634. DOI: 10.3760/j.issn:0254-6450.2007.07.002. [10] 万乃君. 北京市学龄儿童糖代谢异常的流行特征及影响因素[D]. 北京: 北京协和医学院, 2012.Wan NJ. Epidemiological characteristics and influencing factors of abnormal glucose metabolism in school-age children in Beijing[D]. Beijing: Peking Union Medical College, 2012. [11] 洪楠超, 胡承. 青少年与儿童糖尿病[J]. 中国糖尿病杂志, 2016, 24(5): 468-471. DOI: 10.3969/j.issn.1006-6187.2016.05.019.Hong NC, Hu C. Diabetes in adolescents and children[J]. Chin J Diabetes, 2016, 24(5): 468-471. DOI: 10.3969/j.issn.1006-6187.2016.05.019. [12] Sawatsky L, Halipchuk J, Wicklow B. Type 2 diabetes in a four-year-old child[J]. CMAJ, 2017, 189(26): E888-E890. DOI: 10.1503/cmaj.170259. [13] Wang Y, Mi J, Shan XY, et al. Is China facing an obesity epidemic and the consequences The trends in obesity and chronic disease in China[J]. Int J Obes (Lond), 2007, 31(1): 177-188. DOI: 10.1038/sj.ijo.0803354. [14] Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030[J]. Diabetes Care, 2004, 27(5): 1047-1053. DOI: 10.2337/diacare.27.5.1047. [15] Fazeli Farsani S, van der Aa MP, van der Vorst MM, et al. Global trends in the incidence and prevalence of type 2 diabetes in children and adolescents: a systematic review and evaluation of methodological approaches[J]. Diabetologia, 2013, 56(7): 1471-1488. DOI: 10.1007/s00125-013-2915-z. [16] 杨晓炜, 姚立岩, 牛莹莹, 等. 向心性肥胖与2型糖尿病的关系研究[J]. 牡丹江医学院学报, 2010, 31(4): 19-21. DOI:10.3969/j.issn.1001-7550.2010.04.008.Yang XW, Yao LY, Niu YY, et al. Relationship between central obesity and type 2 diabetes mellitus[J]. Journal of Mudanjiang Medical College, 2010, 31(4): 19-21. DOI: 10.3969/j.issn.1001-7550.2010.04.008.Issn.1001-7550.2010.04.008. [17] Lien AS, Tsai JL, Lee JT, et al. A systematic review and meta-analysis of the effect of lifestyle modification on metabolic control in overweight children[J]. Evid Based Complement Alternat Med, 2017, 2017: 1-12. DOI: 10.1155/2017/5681909. [18] 程冷眉, 朱丽萍, 颜玮, 等. 江西省成年居民糖调节受损和糖尿病患病状况及影响因素分析[J]. 中华疾病控制杂志, 2018, 22(5): 494-498. DOI: 10.16462/j.cnki.zhjbkz.2018.05.015.Cheng LM, Zhu LP, Yan W, et al. Analysis of impaired glucose regulation and diabetes status and influencing factors in adult residents in Jiangxi Province[J]. Chin J Dis Control Prev, 2018, 22(5): 494-498. DOI: 10.16462/j.cnki.zhjbkz.2018.05.015. [19] 颜玮, 朱丽萍, 陈轶英, 等. 江西省流动人口糖尿病及糖调节受损影响因素分析[J]. 中华疾病控制杂志, 2015, 19(11): 1105-1108. DOI: 10.16462/j.cnki.zhjbkz.2015.11.007.Yan W, Zhu LP, Chen YY, et al. Analysis of factors affecting diabetes mellitus and impaired glucose regulation in floating population in Jiangxi Province[J]. Chin J Dis Control Prev, 2015, 19(11): 1105-1108. DOI: 10.16462/j.cnki.zhjbkz.2015.11.007. [20] 娄培安, 陈培培, 余加席, 等. 徐州市居民空腹血糖异常危险因素分析[J]. 中华疾病控制杂志, 2011, 15(3): 192-195. http://zhjbkz.ahmu.edu.cn/article/id/JBKZ201103006Lou PA, Chen PP, Yu JX, et al. Analysis of abnormal risk factors of fasting blood glucose in Xuzhou residents[J]. Chin J Dis Control Prev, 2011, 15(3): 192-195. http://zhjbkz.ahmu.edu.cn/article/id/JBKZ201103006