新疆伊犁州35~74岁人群膳食炎症指数与超重/肥胖的关系

符文慧; 罗涛; 裴华莲; 田恬; 王璐; 古丽斯亚·海力力; 戴江红

doi:10.16462/j.cnki.zhjbkz.2020.11.010

新疆伊犁州35~74岁人群膳食炎症指数与超重/肥胖的关系

doi: 10.16462/j.cnki.zhjbkz.2020.11.010

1.
830011 乌鲁木齐，新疆医科大学公共卫生学院流行病与卫生统计学教研室
2.
830000 乌鲁木齐，新疆维吾尔自治区疾病预防控制中心免疫规划所

基金项目:

国家重点研发计划项目 2017YFC0907203

新疆医科大学研究生创新创业启动基金项目 CXCY2018056

详细信息

通讯作者:
戴江红，E-mail：epi102@sina.com

中图分类号: R181
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出版历程
- 收稿日期: 2020-06-10
- 修回日期: 2020-08-19
- 刊出日期: 2020-11-10

Relationship between dietary inflammatory index and overweight/obesity in people aged 35 - 74 years in Yili Prefecture, Xinjiang

1.
Department of epidemiology and statistics, School of Public Health, Xinjiang Medical University, Urumqi 830011, China
2.
Institute for immunization planning, Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi 830011, China

Funds:

National Key Research and Development Plan "Precise Medical Research" Key Special Sub-project 2017YFC0907203

Xinjiang Medical University Graduate Innovation and Entrepreneurship Startup Fund Project CXCY2018056

More Information

Corresponding author: DAI Jiang-hong, E-mail:epi102@sina.com

摘要

摘要: 目的分析膳食炎症指数(dietary inflammatory index，DⅡ)与超重/肥胖之间的关联，为研究肥胖的炎症机制提供科学依据。方法 2019年1月―5月在新疆伊犁州霍城县招募35~74岁队列成员并完成基线调查，采用统一制定的调查问卷，收集研究对象一般人口特征、行为方式等信息。采用食物频率调查表(food frequency questionnaires，FFQ)，调查研究对象膳食摄入情况，计算DⅡ，评估膳食的炎症潜能。结果研究对象2 241人，超重的检出率为38.51%，肥胖的检出率为32.04%；总研究对象DⅡ评分以正值为主，总体膳食属于促炎性膳食；调整年龄、民族、性别、文化程度、家庭收入后，Log-binomial回归分析模型结果显示DⅡ与超重及肥胖存在相关性，最大促炎组患超重及肥胖的风险是最大抗炎组的1.32倍(PR=1.32，95% CI：1.10~1.57，P=0.015)，其中DⅡ与超重仅在Q1(最大抗炎)与Q4(最大促炎)组间发现相关性(PR=1.26，95% CI：1.09~1.47，P=0.002)，DⅡ与肥胖在每组均存在相关性，随着DⅡ评分的增加，研究对象患肥胖的风险增加。结论膳食炎症指数与超重/肥胖之间存在相关性，膳食的肥胖效应可以从炎症的角度进行深入分析。
- 新疆 /
- 成年人 /
- 膳食炎症指数 /
- 肥胖
Abstract: Objective To analyze the association between dietary inflammation index (DⅡ) and overweight/obesity, and to provide scientific basis for studying the inflammatory mechanism of obesity. Methods From January to May 2019, the subjects were all adults aged 35-74 years old in the baseline participating in the Xinjiang multi-ethnic natural population cohort construction and health follow-up study. The general demographic characteristics and behavior patterns of the subjects were collected by using an unified questionnaire. The DⅡ score was calculated from a diet intake assessed by 127 food frequency questionnaires (FFQ). Results Among the 2 241 participants, the detection rate of overweight and obesity was 38.51% and 32.04%. Log-binomial regression analyses were used to estimate the prevalence ratios (PRs) and 95% confidence intervals (95% CIs) of DⅡ in relation to overweight/obesity. After adjusting for potential confounders, compared with the 1st quintile group, subjects from the 4th quintile group had a higher risk of overweight/obesity (PR = 1.32, 95% CI: 1.10-1.57, P=0.015). The association between DⅡ and overweight was only found between the 1st quintile group and the 4th quintile group (PR=1.26, 95% CI:1.09-1.47, P=0.002), but compared with the 1st quintile group, subjects from other groups all had higher risk of obesity. Conclusions There was a correlation between the dietary inflammatory index and overweight/obesity, the obesity effect of diet could be analyzed from the perspective of inflammation.
- Xinjiang /
- Adult /
- Dietary inflammatory index /
- Obesity

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图 1 DⅡ的分布

Figure 1. The distribution of DⅡ

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表 1 不同研究对象超重、肥胖检出率的差异[n(%)]

Table 1. The different detection rate of overweight and obesity among different subjects [n(%)]

变量	超重组	肥胖组	总计	χ²值	P值
年龄(岁)				11.50	0.022
35~	270(37.30)	209(28.90)	723(32.30)
46~	304(39.40)	265(34.40)	771(34.40)
56~74	288(38.60)	244(32.70)	747(33.30)
性别				21.18	< 0.001
男性	450(41.00)	301(27.40)	1 098(49.00)
女性	413(36.1)	417(36.5)	1 143(51.00)
民族				59.67	< 0.001
汉族	202(47.0)	108(25.10)	430(19.20)
哈萨克族	369(39.3)	325(34.60)	940(41.90)
回族	67(37.60)	74(41.60)	178(7.90)
维吾尔族	205(31.40)	198(30.30)	653(29.10)
其他	20(50.0)	13(32.50)	40(1.80)
文化程度				6.74	0.150
小学及以下	650(38.80)	551(32.90)	1 675(74.70)
初中、高中及以上	213(37.60)	167(29.50)	566(25.30)
家庭年收入(万元)				12.02	0.017
＜1.0	101(44.50)	62(27.30)	227(10.10)
1.0~	616(38.30)	502(31.20)	1 610(71.80)
＞3.5	146(36.10)	154(38.10)	404(18.00)

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表 2 不同特征研究对象DⅡ的分布比较[n(%)]

Table 2. Comparison of the distribution of DⅡ with different characteristics [n(%)]

变量	Q1	Q2	Q3	Q4	χ²值	P值
年龄(岁)					7.34	0.025
35~	194(26.80)	181(25.00)	180(24.90)	168(23.20)
46~	200(25.90)	197(25.60)	188(24.40)	186(24.10)
56~74	166(22.30)	182(24.40)	189(25.30)	209(28.00)
民族					29.98	< 0.001
汉族	133(30.90)	117(27.20)	97(22.60)	83(19.30)
哈萨克族	231(24.60)	236(25.10)	254(27.00)	219(23.30)
回族	57(32.00)	47(26.40)	42(23.60)	32(18.00)
维吾尔族	131(20.10)	147(22.50)	156(23.90)	219(33.50)
其他	8(20.00)	13(32.50)	9(22.50)	10(25.00)
文化程度					31.92	< 0.001
小学及以下	385(23.00)	396(23.60)	433(25.90)	461(27.50)
初、高中及以上	175(31.10)	164(28.40)	125(22.40)	102(18.10)
家庭年收入(万)					7.51	0.023
＜1.0	55(24.20)	56(24.70)	60(26.40)	56(24.70)
1.0~	371(23.00)	418(26.00)	411(25.50)	410(25.50)
＞3.5	134(33.20)	86(21.30)	87(21.50)	97(24.00)
BMI(kg/m²)					11.03	0.004
18.5~	195(29.50)	160(24.20)	158(23.90)	147(22.30)
24.0~	211(24.40)	217(25.10)	216(25.00)	219(25.40)
≥28.0	151(21.00)	187(26.00)	186(25.90)	194(27.00)
体力活动					7.24	0.027
从不锻炼	9(64.30)	2(14.30)	1(7.10)	2(14.30)
偶尔锻炼	526(24.40)	547(25.40)	537(25.00)	542(25.20)
经常锻炼	25(33.30)	11(14.70)	20(26.70)	19(25.30)

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表 3 DⅡ与超重/肥胖的关联性分析

Table 3. Association between DⅡ and overweight/obesity

DⅡ分类	超重/肥胖	PR(95% CI)值	P值	超重	PR(95% CI)值	P值	肥胖	PR(95% CI)值	P值
Q1	362	1.00		211	1.00		151	1.00
Q2	404	1.07(0.88~1.29)	0.619	217	1.07(0.90~1.25)	0.430	187	1.62(1.16~2.25)	0.005
Q3	402	1.10(0.91~1.33)	0.462	216	1.07(0.90~1.25)	0.440	186	1.66(1.19~2.33)	0.003
Q4	413	1.32(1.10~1.57)	0.015	219	1.26(1.09~1.47)	0.002	194	1.91(1.36~2.70)	＜0.001

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