反式脂肪酸与慢性非传染性疾病关系研究进展

李艳茹; 吴亚; 冯月梅; 殷建忠

doi:10.16462/j.cnki.zhjbkz.2020.11.017

反式脂肪酸与慢性非传染性疾病关系研究进展

doi: 10.16462/j.cnki.zhjbkz.2020.11.017

李艳茹¹,
吴亚¹,
冯月梅¹,
殷建忠^{1, 2, ,}

1.
650500 昆明，昆明医科大学公共卫生学院
2.
678000 保山，保山中医药高等专科学校

基金项目:

国家自然科学基金 81860597

国家重点研发计划“精准医学”重点专项课题 2017YFC0907302

详细信息

通讯作者:
殷建忠，E-mail：yinjianzhong2005@sina.com

中图分类号: R151.2
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- 被引次数: 0
出版历程
- 收稿日期: 2020-04-12
- 修回日期: 2020-05-29
- 刊出日期: 2020-11-10

Advances on the relationship between trans fatty acids and chronic diseases

1.
School of Public Health, Kunming Medical University, Kunming 650500, China
2.
Baoshan College of Traditional Chinese Medicine, Baoshan 678000, China

Funds:

National Natural Science Foundation of China 81860597

National Key Research and Development Plan "precision medicine" Key Special Subject 2017YFC0907302

More Information

Corresponding author: YIN Jian-zhong,E-mail：yinjianzhong2005@sina.com

摘要

摘要: 随着膳食模式的改变，主要存在于加工食品中的膳食反式脂肪酸(trans fatty acid，TFA)通过饮食摄入在身体中慢慢累积。在国外很早就有学者研究TFA的种类、来源、结构以及对疾病的影响，但是在国内TFA对疾病的危害还没有引起足够的重视。本文就近几年TFA对肥胖、心血管疾病、糖尿病、非酒精性脂肪肝、癌症等慢性非传染性疾病(简称慢性病)的危害及作用机制做讨论，为疾病预防和治疗、营养膳食指导、工业生产优化等方面提供参考依据。
- 反式脂肪酸 /
- 肥胖 /
- 心血管疾病 /
- 糖尿病 /
- 非酒精性肝病 /
- 癌症
Abstract: With the change of dietary patterns, dietary trans fatty acids (TFA), which mainly presents in processed foods, accumulates slowly in the body through dietary intake. Scholars have studied the types, sources, structures, and effects of TFA on diseases very early in foreign countries, but the harm of TFA to diseases in China has not attracted enough attention. This article discusses the harm and mechanism of TFA in recent years on obesity, cardiovascular disease, diabetes, non-alcoholic fatty liver, cancer and other chronic diseases, and provides reference for disease prevention and treatment, nutrition and diet guidance, as well as industrial production optimization.
- Trans fatty acids /
- Obesity /
- Cardiovascular disease /
- Diabetes /
- Non-alcoholic liver disease /
- Cancer

HTML全文

图 1 顺式脂肪酸与反式脂肪酸结构简式图

(以油酸和反油酸为例)

Figure 1. Simple structure diagram of cis fatty acids and trans fatty acids

(take oleic acid and trans-oleic acid for example)

下载: 全尺寸图片幻灯片

表 1 日常膳食中常见的反式脂肪酸种类

Table 1. Classification of common trans fatty acids in diets

中文名	英文名	分子简式
反棕榈酸	Trans palmitoleic acid	C16:1 9t
反油酸	Elaidic acid(EA)	C18:1 9t
反-10-十八碳烯酸	Trans-10-octadecenoic acid	C18:1 10t
反异油酸	Trans vaccenic acid (TVA)	C18:1 11t
瘤胃酸	Rumenic acid	C18:2 9c, 11t
反亚油酸	Trans, trans-9, 12-octadecadienoic acid	C18:2 9t, 12t

下载: 导出CSV

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