Epidemiological characteristics of 17 coronavirus disease 2019 in Puyang, Henan
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摘要:
目的 探讨河南省濮阳市COVID-19病例的流行病学特征,为疾病防控提供依据。 方法 收集濮阳市17例COVID-19确诊病例的流行病学资料,通过绘制发病时序图、病例关系图描述和分析其时间、地点及人群分布特征。 结果 17例确诊病例中,男性7例(41.2%)。年龄在12~66岁之间,中位数36岁。共发生4起聚集性疫情,涉及病例12例(70.6%),均涉及家庭续发病例。中位潜伏期为6.5 d,最短3 d,最长13 d。其中,1例二代病例的发病时间比指示病例早11 d。发病-就诊间隔的中位时间为4 d,最短0 d,最长12 d。17例病例中,有6例14 d内有湖北旅居史,1例有境外旅游史。其余病例均为本地感染者,其中8例为确诊病例的密切接触者,2例传染来源不明。密切接触者中,家庭聚集性病例的传染途径包括密切接触传播和呼吸道传播。小区续发病例的传播途径推断为楼梯间飞沫传播。 结论 濮阳市以家庭聚集性疫情为主,且指示病例大部分为湖北传入性病例,潜伏期病例存在传染可能。 Abstract:Objective To explore the epidemiological characteristics of confirmed cases of coronavirus diseases 2019 (COVID-19) in Puyang, Henan Province, so as to provide basis for diseases control and preventive. Methods The epidemiological data of 17 cases of COVID-19 in Puyang were collected, and the time, regional and population distribution characteristics of COVID-19 were described and analyzed by drawing disease sequence diagram and case relationship diagram. Results Among the 17 cases, 7 were male (41.2%); the median age was 36 years old with age ranged from 12 to 66 years. A total of 4 clustered outbreaks occurred, involving 12 cases (70.6%), all of which were family recurrent cases. The median incubation period was 6.5 days, the shortest 3 days and the longest 13 days. The onset time of a second-generation case was 11 days earlier than that of the indicator case. The median time between onset and treatment was 4 days, the shortest was 0 days and the longest was 12 days. Of the 17 cases, 6 had a sojourning history in Hubei Province within 14 days, and 1 had a history of overseas tourism. The other cases were all local infections, 8 of them were close contacts of the confirmed cases, and 2 of them were from unknown sources. Among the close contacts, the cases involved in the family clustering epidemic were transmitted through close contact and respiratory tract. After detailed investigation and inquiry, it was inferred that the transmission route was the staircase droplet transmission. Conclusion In Puyang City, most of the cases were from Hubei Province, and was dominated by family clustering epidemic. There was a possibility of infection in the incubation period. -
Key words:
- COVID-19 /
- Epidemiological characteristics /
- Incubation period
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表 1 17例濮阳市COVID-19病例发病和确诊时间分布
Table 1. Temporal distribution of the 17 COVID-19 cases onset and diagnosis
序号 年龄(岁) 性别 暴露日期 发病日期 就诊日期 确诊日期 暴露-发病间隔(d) 发病-就诊间隔(d) 状况(截至2020.02.26) 病例1 34 女 2020.01.13 2020.01.24 2020.01.27 2020.01.28 11 3 2020.02.17出院 病例2 36 男 2020.01.21 2020.01.24 2020.01.24 2020.01.30 3 0 重型,2020.02.15出院 病例3 34 女 2020.01.25 2020.01.26 2020.01.30 1 2020.02.10出院 病例4 37 女 2020.01.16 2010.01.23 2020.02.03 2020.02.02 7 11 在院 病例5 12 男 2020.02.04 2020.02.07 2020.02.05 3 2020.02.17出院 病例6 56 男 2020.01.21 2020.01.26 2020.02.05 2020.02.07 5 10 2020.02.18出院 病例7 43 女 2020.01.18 2020.01.27 2020.02.05 2020.02.07 9 9 2020.02.18出院 病例8 59 男 2020.01.21 2020.02.05 2020.02.08 2020.02.08 15 3 在院 病例9 55 女 2020.01.31 2020.02.07 2020.02.08 7 危重型,2月16日转省医院 病例10 50 女 2020.01.21 2020.01.27 2020.02.08 2020.02.09 6 12 在院 病例11 33 男 2020.01.13 2020.01.24 2020.02.03 2020.02.10 11 10 2020.02.18出院 病例12 65 男 2020.01.22 2020.02.03 2020.02.09 2020.02.11 12 6 在院 病例13 18 女 2020.01.25 2020.02.10 2020.02.10 2020.02.11 16 0 在院 病例14 27 女 2020.01.25 2020.02.03 2020.02.10 2020.02.14 9 7 在院 病例15 26 男 2020.01.21 2020.02.12 2020.02.13 2020.02.14 22 1 在院 病例16 29 女 2020.01.28 2020.02.09 2020.02.13 2020.02.14 12 4 在院 病例17 66 女 2020.01.29 2020.02.09 2020.02.13 2020.02.14 11 4 在院 -
[1] 国家卫生健康委办公厅, 国家中医药管理局办公室. 新型冠状病毒防控方案(第四版)[EB/OL]. (2020-02-06)[2020-03-14]. http://www.gov.cn/zhengce/zhengceku/2020-02/07/content_5475813.htm.General Office of National Health Commission, General Office of National Administration of Traditional Chinese Medicine. Prevention and Control Plan for Novel Coronavirus Pneumonia (Version 4)[EB/OL]. (2020-02-06)[2020-03-14]. http://www.gov.cn/zhengce/zhengceku/2020-02/07/content_5475813.htm. [2] 国家卫生健康委办公厅, 国家中医药管理局办公室. 新型冠状病毒肺炎诊疗方案(试行第五版)[EB/OL]. (2020-02-08)[2020-03-14]. http://www.gov.cn/zhengce/zhengceku/2020-02/09/content_5476407.htm.General Office of National Health Commission, General Office of National Administration of Traditional Chinese Medicine. Diagnostic and Treatment Plan for Novel Coronavirus Pneumonia (Trial Version 5)[EB/OL]. (2020-02-08)[2020-03-14]. http://www.gov.cn/zhengce/zhengceku/2020-02/09/content_5476407.htm. [3] 中华预防医学会新型冠状病毒肺炎防控专家组. 新型冠状病毒肺炎流行病学特征的最新认识[J]. 中华流行病学杂志, 2020, 41(2): 139-144. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.002.Special expert group for control of the epidemic of novel coronavirus pneumonia of Chinese Preventive Medicine Association. An update on the epidemiological characteristics of an outbreak of novel coronavirus pneumonia (COVID-19)[J]. Chin J Epidemiol, 2020, 41(2): 139-144. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.002. [4] Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study[J]. Lancet, 2020, 395(10223): 507-513. DOI: 10.1016/S0140-6736(20)30211-7. [5] Guan W, Ni Z, Hu Y, et al. Clinical characteristics of 2019 novel coronavirus infection in China[J]. N Engl J Med, 2020, 382(18): 1708-1720. DOI: 10.1056/NEJMoa2002032. [6] 陈伟, 王晴, 李媛秋, 等. 我国新型冠状病毒肺炎疫情早期围堵策略概述[J]. 中华预防医学杂志, 2020, 54(3): 239-243. DOI: 10.3760/cma.j.issn.0253-9624.2020.03.003.Chen W, Wang Q, Li YQ, et al. Early containment strategies and core measures for prevention and control of novel coronavirus pneumonia in China[J]. Chin J Prev Med, 2020, 54(3): 239-243. DOI: 10.3760/cma.j.issn.0253-9624.2020.03.003. [7] Zhang L, Liu Y. Potential interventions for novel coronavirus in China: a systematic review[J]. J Medical Virol, 2020, 92(5): 479-490. DOI: 10.1002/jmv.25707. [8] 中国疾病预防控制中心新型冠状病毒肺炎应急响应机制流行病学组. 新型冠状病毒肺炎流行病学特征分析[J]. 中华流行病学杂志, 2020, 41(2): 145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003.The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team of Chinese Center for Diseases Control and Prevention. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China[J]. Chin J Epidemiol, 2020, 41(2): 145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003. [9] Chan JF, Yuan S, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster[J]. Lancet, 2020, 395(10223): 514-523. DOI: 10.1016/S0140-6736(20)30154-9.