六安市69例新型冠状病毒肺炎病例的流行病学特征

魏倩楠; 易伟卓; 潘如兵; 李开春; 储昭阳; 俞亮; 袁伟; 魏祥; 张勤; 冷瑞雪; 潘海峰; 王盈; 陶莎莎; 叶冬青; 苏虹

doi:10.16462/j.cnki.zhjbkz.2021.04.010

六安市69例新型冠状病毒肺炎病例的流行病学特征

doi: 10.16462/j.cnki.zhjbkz.2021.04.010

魏倩楠¹,
易伟卓¹,
潘如兵¹,
李开春²,
储昭阳³,
俞亮⁴,
袁伟⁴,
魏祥⁵,
张勤¹,
冷瑞雪¹,
潘海峰¹,
王盈¹,
陶莎莎¹,
叶冬青^1, ,,
苏虹^1, ,

1.
230032 合肥，安徽医科大学公共卫生学院流行病与卫生统计学系，炎症免疫性疾病安徽省实验室
2.
237000 六安，六安市疾病预防控制中心
3.
237200 六安，六安市霍山县疾病预防控制中心
4.
237300 六安，六安市金寨县疾病预防控制中心
5.
237400 六安，六安市霍邱县疾病预防控制中心

基金项目:

安徽医科大学第二批新型冠状病毒肺炎疫情应急科研攻关项目 YJGG202005

详细信息

通讯作者:
苏虹，E-mail: suhong5151@sina.com

叶冬青，E-mail: ydq@ahmu.edu.cn

中图分类号: R181
计量
- 文章访问数: 407
- HTML全文浏览量: 187
- PDF下载量: 57
- 被引次数: 0
出版历程
- 收稿日期: 2020-07-22
- 修回日期: 2020-10-12
- 网络出版日期: 2021-05-11
- 刊出日期: 2021-04-10

Epidemic characteristics of 69 COVID-19 cases in Lu'an City

1.
Department of Epidemiology and Health Statistics, School of Public Health, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei 230032, China
2.
Lu'an Center for Disease Control and Prevention, Lu'an 237000, China
3.
Huoshan Center for Disease Control and Prevention, Lu'an 237200, China
4.
Jinzhai Center for Disease Control and Prevention, Lu'an 237300, China
5.
Huoqiu Center for Disease Control and Prevention, Lu'an 237400, China

Funds:

The Second Batch of Emergency Research Project of Coronavirus Disease 2019 in Anhui Medical University YJGG202005

More Information

Corresponding author: YE Dong-qing, E-mail: ydq@ahmu.edu.cn; SU Hong, E-mail: suhong5151@sina.com

摘要

摘要: 目的探究六安市COVID-19病例的流行特征，为该地COVID-19疫情防控提供科学依据。方法选取截至2020年2月18日24时传染病报告系统中六安市所有COVID-19确诊病例，收集一般人口学特征、病例发病和就诊信息、流行病学特征等资料描述病例特征，采用SaTScan 9.6.0.0软件分析疾病传播的时空分布特征，应用Excel 2010软件绘制流行曲线。结果六安截至2020年2月18日共报告确诊病例69例，男性(44例)多于女性(25例)，年龄集中在36~45岁(37.68%)，工人最多(24.64%)。首发症状以发热(50例，72.46%)、咳嗽(25例，36.23%)和乏力(12例，17.40%)为主。全市以金寨县(23例)、霍山县(17例)和霍邱县(13例)疫情最严重。发病数于1月25~28日出现首个流行峰，1月27日出现单日最高，后呈下降趋势。共发生45例聚集性病例。结论六安市COVID-19疫情总体可防可控，后期需警惕家庭聚集性和无症状感染者以及输入性病例传播的风险，做好密切接触者的排查工作。
- 新型冠状病毒肺炎 /
- 流行特征 /
- 聚集性病例
Abstract: Objective To explore the epidemic characteristics of COVID-19 in Lu'an city, so as to provide scientific basis for the prevention and control of COVID-19 in this area. Methods All the confirmed cases of COVID-19 were selected from the Infectious Disease Reporting System from the onset of disease to 24:00 on February 18th, 2020 in Lu'an City. The general demographic, onset and medical information, and epidemiological characteristics of confirmed cases were collected to describe the feature of patients. The spatial and temporal distribution of disease transmission was analyzed by SaTScan 9.6.0.0 software, and Excel 2010 software was used to draw the epidemic curves of all cases. Results A total of 69 confirmed cases were reported in Lu'an City by February 18th, 2020. There were more male cases (44) than female (25), and cases mainly aged 36-45 years old (37.68%). The proportion of workers was the highest (24.64%). The first symptom of conformed cases was fever (50, 72.46%), cough (25, 36.23%) and fatigue (12, 17.40%). The epidemic was more serious in Jinzhai County (23), Huoshan County (17) and Huoqiu County (13). The number of cases in Lu'an showed that the first epidemic peak occurred between January 25th and January 28th, and the largest number of cases occurred on January 27th, then showed a downward trend. A total of 45 aggregate cases were found. Conclusion The COVID-19 epidemic in Lu'an City is generally preventable and controllable. It will be alert to the risk of family clustering, spread of asymptomatic infections and imported cases. Future work should focus on the investigation of close contacts.
- Coronavirus disease 2019 /
- Epidemic characteristics /
- Clustering cases

HTML全文

图 1 截至2020年2月18日六安市COVID-19病例分布图

Figure 1. Spatial distribution of COVID-19 confirmed cases in Lu'an City by February 18th, 2020

下载: 全尺寸图片幻灯片

图 2 截至2020年2月18日六安市COVID-19发病的流行曲线

Figure 2. Epidemic curve of onset of COVID-19 confirmed cases in Lu'an City by February 18th, 2020

下载: 全尺寸图片幻灯片

图 3 六安市COVID-19病例发病日期、就诊日期、确诊日期分布

Figure 3. Distribution of date of onset, treament and diagnosis of COVID-19 cases in Lu'an City

下载: 全尺寸图片幻灯片

图 4 8例家庭聚集性病例的发病、接触机会以及核酸检测阳性的时间序列图

Figure 4. The time series of onset, exposure, and positive nucleic acid test of 8 cases in one family clustering

下载: 全尺寸图片幻灯片

表 1 六安市COVID-19病例的基本特征及构成比

Table 1. The number and constituent ratio of demographic information of COVID-19 confirmed cases in Lu'an City

病例特征	人数(例)	构成比(%)
性别
男	44	63.77
女	25	36.23
年龄(岁)
＜19	2	2.90
19~＜36	19	27.54
36~＜46	26	37.68
46~＜61	13	18.84
≥61	9	13.04
职业
工人	17	24.64
商业人员	16	23.19
农民	16	23.19
技术人员	6	8.69
退休	2	2.90
学生	1	1.44
无业	6	8.70
缺失	5	7.25
聚集性病例
是	45	65.22
否	24	34.78
输入史
武汉输入	18	26.09
其他地区输入	12	17.39
本地病例	39	56.52

下载: 导出CSV

表 2 六安市COVID-19病例不同临床特征人数及构成比

Table 2. The number and constituent ratio of COVID-19 confirmed cases with different clinical characteristics in Lu'an City

变量	出现该症状人数(例)	构成比(%)
首发症状
发热	50	72.46
咳嗽	25	36.23
乏力	12	17.40
干咳	7	10.14
寒战	5	7.25
咽痛	5	7.25
头痛	5	7.25
胸闷	5	7.25
无症状	7	10.14
肌肉酸痛	3	4.35
恶心	3	4.35
腹泻	3	4.35
流涕	3	4.35
鼻塞	2	2.90
呼吸困难	1	1.45
腹痛	1	1.45
转归
病情稳定	37	53.62
治愈出院	30	43.48
加重	2	2.90

下载: 导出CSV

参考文献(17)

[1]	Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus infected pneumonia in Wuhan, China[J]. JAMA, 2020, 323(11): 1061-1069. DOI: 10.1001/jama.2020.1585.
[2]	Wang C, Horby PW, Hayden FG, et al. A novel coronavirus outbreak of global health concern[J]. Lancet, 2020, 395(10223): 470-473. DOI: 10.1016/S0140-6736(20)30185-9.
[3]	World Health Organization. WHO characterizes COVID-19 as a pandemic[EB/OL]. (2020-03-13)[2020-07-09]. https://www.paho.org/hq/index.php?option=com_content&view=article&id=15756:who-characterizes-COVID-19-as-a-pandemic&Itemid=1926&lang=en.
[4]	Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China[J]. Lancet, 2020, 395(10223): 497-506. DOI: 10.1016/S0140-6736(20)30183-5.
[5]	Paules CI, Marston HD, Fauci AS. Coronavrius infection more than just the common cold[J]. JAMA, 2020, 323(8): 707-708. DOI: 10.1001/jama.2020.0757.
[6]	中国疾病预防控制中心新型冠状病毒肺炎应急响应机制流行病学组. 新型冠状病毒肺炎流行病学特征分析[J]. 中华流行病学杂志, 2020, 41(2): 145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003. Epidemiology Working Group for NCIP Epidemic Response of Chinese Disease Control and Prevention. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China[J]. Chin J Epidemiol, 2020, 41(2): 145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003.
[7]	中华人民共和国中央人民政府. 国家卫生健康委办公厅关于印发新型冠状病毒肺炎防控方案(第四版)的通知[EB/OL]. (2020-02-06)[2020-07-09]. http://www.gov.cn/zhengce/zhengceku/2020-02/07/content_5475813.htm. Central People's Government of the People's Republic of China. Notice of the General Office of the National Health Commission on printing and distributing 2019 Novel Coronavirus Diseases (COVID-19) Prevention and Vontrol Plan (Fourth Edition)[EB/OL]. (2020-02-06)[2020-07-09]. http://www.gov.cn/zhengce/zhengceku/2020-02/07/content_5475813.htm.
[8]	中国疾病预防控制中心. 新型冠状病毒肺炎聚集性疫情流行病学调查指南[EB/OL]. (2020-02-13)[2020-07-09]. http://www.chinacdc.cn/jkzt/crb/zl/szkb_11803/jszl_11815/202002/t20200220_213405.html. Chinese Center for Disease Control and Prevention. A guide to the epidemiological investigation of 2019 novel coronavirus diseases (COVID-19) cluster epidemic[EB/OL]. (2020-02-13)[2020-07-09]. http://www.chinacdc.cn/jkzt/crb/zl/szkb_11803/jszl_11815/202002/t20200220_213405.html.
[9]	方峰, 罗小平. 面对2019新型冠状病毒感染重大疫情: 儿科医生的思考[J]. 中华儿科杂志, 2020, 58(2): 81-85. DOI: 10.3760/cma.j.issn.0578-1310.2020.02.001. Fang F, Luo XP. Facing the pandemic of 2019 novel coronavirus infections: the pediatric perspectives[J]. Chin J Pediatr, 2020, 58(2): 81-85. DOI: 10.3760/cma.j.issn.0578-1310.2020.02.001.
[10]	李宝珠, 曹钕威, 周浩月, 等. 安徽省新型冠状病毒肺炎流行病学特征[J]. 中华疾病控制杂志, 2020, 24(5): 506-511. DOI: 10.16462/j.cnki.zhjbkz.2020.05.003. Li BZ, Cao NW, Zhou HY, et al. Epidemiological characteristics of coronavirus disease 2019 in Anhui Province[J]. Chin J Dis Control Prev, 2020, 24(5): 506-511. DOI: 10.16462/j.cnki.zhjbkz.2020.05.003.
[11]	蒋荣猛. 新型冠状病毒感染相关概念的解读[J]. 中国感染控制杂志, 2020, 19(6): 487-491. DOI: 10.12138/j.issn.1671-9638.20206157. Jiang RM. Interpretation on concepts relevant to 2019-nCoV infection[J]. Chin J Infec Contrl, 2020, 19(6): 487-491. DOI: 10.12138/j.issn.1671-9638.20206157.
[12]	镇万源, 蒋正文, 王望才, 等. 32例新型冠状病毒无症状感染者的临床特征分析[J]. 武汉大学学报(医学版), 2021, 42(1): 23-27. DOI: 10.14188/j.1671-8852.2020.0334. Zhen WY, Jiang ZW, Wang WC, et al. Clinical characteristics of 32 asymptomatic patients infected with novel coronavirus[J]. Med J Wuhan Univ, 2021, 42(1): 23-27. DOI: 10.14188/j.1671-8852.2020.0334.
[13]	李锦成, 徐勤, 王艳, 等. 江苏省扬州市新型冠状病毒肺炎无症状感染者的特征分析[J]. 实用临床医药杂志, 2020, 24(5): 10-13. DOI: 10.7619/jcmp.202005003. Li JC, Xu Q, Wang Y, et al. Analysis in characteristics of asymptomatic infection patients with coronavirus disease 2019 in Yangzhou City of Jiangsu Province[J]. Journal of Clinical Medicine in Practice, 2020, 24(5): 10-13. DOI: 10.7619/jcmp.202005003.
[14]	Rothe C, Schunk M, Sothmann P, et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany[J]. N Engl J Med, 2020, 382(10): 970-971. DOI: 10.1056/NEJMc2001468.
[15]	Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019[J]. N Engl J Med, 2020, 382(8): 727-733. DOI: 10.1056/NEJMoa2001017.
[16]	中华人民共和国国家卫生健康委员会. 截至7月13日24时全国新型冠状病毒肺炎疫情最新情况[EB/OL]. (2020-07-14)[2020-07-14]. http://www.nhc.gov.cn/xcs/yqfkdt/202007/8618a0cea9934f6ab59af2320103a78c.shtml. National Health Commission of the People's Republic of China. The latest situation of the COVID-19 epidemic situation by 24: 00, July 13th. [EB/OL]. (2020-07-14)[2020-07-14]. http://www.nhc.gov.cn/xcs/yqfkdt/202007/8618a0cea9934f6ab59af2320103a78c.shtml.
[17]	北京市卫生健康委员会. 北京市新冠肺炎疫情相关情况[EB/OL]. (2020-07-09)[2020-07-13]. http://wjw.beijing.gov.cn/xwzx_20031/wnxw/202007/t20200713_1947135.html. Beijing Municipal Health Commission. Beijing 2019 novel coronavirus diseases (COVID-19) epidemic situation[EB/OL]. (2020-07-09)[2020-07-13]. http://wjw.beijing.gov.cn/xwzx_20031/wnxw/202007/t20200713_1947135.html.