Risk factors of chronic diseases among adult residents in Nanjing City from 2017 to 2018
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摘要:
目的 了解南京市成人居民慢性病相关危险因素流行特征、关联性和聚集性。 方法 利用2017―2018年南京市慢性病及其危险因素监测数据,分析≥18岁居民慢性病4项主要行为危险因素(现在吸烟、有害饮酒、蔬菜水果摄入不足及身体活动不足)和4项主要代谢危险因素(超重/肥胖、血压升高、血糖升高及血脂异常)的流行特征,采用多水平模型分析慢性病危险因素间的关联性及其聚集性。 结果 共纳入60 283名研究对象。蔬菜水果摄入不足、身体活动不足、现在吸烟及有害饮酒的比例分别为49.94%、28.19%、22.26%及7.40%,超重/肥胖、血脂异常、血压升高及血糖升高的比例分别为43.00%、28.35%、26.02%及9.39%。8项危险因素间存在20对正相关关系,差异均有统计学意义(均有P < 0.05)。0、1、2和≥3项危险因素的比例分别为15.09%、29.94%、26.17%和28.80%。男性、高年龄、郊县、低教育水平、离退休以及丧偶/离异/分居人群危险因素聚集的风险较高(均有P < 0.05)。 结论 南京市成人慢性病危险因素暴露率较高,两两间存在正向相关,针对重点人群应实施多种危险因素综合的防控策略。 Abstract:Objective To estimate the prevalence, clustering and association of risk factors in adult residents in Nanjing City. Methods Using the data of chronic diseases and risk factors surveillance in Nanjing City from 2017 to 2018, 4 behavioral risk factors (current smoking, harmful drinking, insufficient intake of fruits and vegetables, and insufficient physical activity) and 4 metabolic risk factors (overweight/obesity, raised blood pressure, raised fasting plasma glucose, and dyslipidemia) were analyzed in different characteristics of adults in Nanjing; and multilevel model was applied to analyze the association and clustering of chronic disease risk factors. Results A total of 60 283 community-dwelling adults included in this study were selected randomly. The proportions of insufficient intake of fruits and vegetables, insufficient physical activity, current smoking, and harmful drinking were 49.94%, 28.19%, 22.26%, and 7.40%, respectively; Overweight/obesity, dyslipidemia, raised blood pressure and raised fasting plasma glucose were 43.00%, 28.35%, 26.02%, and 9.39%, respectively. There were 20 pairs of postive correlations between the 8 risk factors, and the differences were statistically significant (all P < 0.05). The proportions of 0, 1, 2, and 3 or more risk factors were 15.09%, 29.94%, 26.17%, and 28.08%, respectively. Males, high age, suburbs, low education, retired, widowed/divorced/separated people were at higher risk of clustering risk factors (all P < 0.05). Conclusions The exposure rate of chronic disease behavior and metabolic risk factors of adult residents in Nanjing City were relatively high, and there was a positive correlation between different risk factors. Comprehensive prevention and control strategies for multiple risk factors should be implemented for key populations. -
Key words:
- Chronic diseases /
- Behavior risk factors /
- Metabolic risk factors
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表 1 2017年―2018年南京成人居民主要慢性病危险因素流行特征
Table 1. The prevalence of main chronic disease risk factors among adult residents in Nanjing from 2017 to 2018
变量 总人群(N=60 283) 性别 t/F/U/χ2值 P值 男性(n=29 848) 女性(n=30 435) 行为因素 日均吸烟量(支) a 10.25±5.91 10.34±5.92 7.48±5.30 6.792 < 0.001 日均饮酒量(g) a 13.60±3.16 25.02±4.01 2.46±1.22 92.429 < 0.001 日均蔬菜水果摄入量(g) a 433.92±281.13 422.99±276.03 444.65±285.63 10.188 < 0.001 每周身体活动量(METs) b 3 220.00(1 200.00,6 480.00) 3 100.00(1 120.00,6 300.00) 3 360.00(1 200.00,6 720.00) 5.993 < 0.001 代谢因素a BMI(kg/m2) 23.78±3.29 24.32±3.11 23.25±3.37 43.373 < 0.001 DBP(mm Hg) 77.67±14.28 79.15±13.90 76.23±14.49 25.569 < 0.001 SBP(mm Hg) 124.55±19.29 126.65±17.90 122.50±20.40 28.161 < 0.001 FPG(mmol/L) 5.34±1.53 5.42±1.60 5.26±1.46 11.623 < 0.001 LDL-C(mmol/L) 2.64±0.87 2.63±0.86 2.65±0.87 2.970 0.003 HDL-C(mmol/L) 1.47±0.52 1.41±0.53 1.52±0.51 25.282 < 0.001 TG(mmol/L) 1.51±0.94 1.61±1.09 1.41±0.96 21.332 < 0.001 TC(mmol/L) 4.62±1.18 4.58±1.10 4.67±1.13 10.846 < 0.001 行为危险因素(%) c 现在吸烟率 22.26(21.93~22.60) 43.45(42.89~44.02) 1.49(1.35~1.62) 15 335.528 < 0.001 有害饮酒率 7.40(7.19~7.61) 13.28(12.89~13.66) 1.64(1.49~1.78) 2 980.068 < 0.001 蔬菜水果摄入不足率 49.94(49.51~50.37) 48.33(47.73~48.94) 51.52(50.92~52.12) 53.216 < 0.001 身体活动不足率 28.19(27.83~28.55) 31.10(30.57~31.62) 25.34(24.85~25.83) 246.832 < 0.001 代谢危险因素(%) c 超重/肥胖率 43.00(42.61~43.40) 51.10(50.53~51.66) 35.06(34.53~35.60) 1 580.629 < 0.001 血压升高率 26.02(25.67~26.37) 28.74(28.23~29.26) 23.35(22.88~23.83) 227.503 < 0.001 血糖升高率 9.39(9.16~9.63) 10.33(9.99~10.68) 8.47(8.16~8.79) 61.155 < 0.001 血脂异常率 28.35(27.99~28.71) 30.77(30.25~31.30) 25.98(25.49~26.48) 170.150 < 0.001 注:a正态分布的定量资料以(x±s)表示,组间比较采用t/F检验;b偏态分布的定量资料以M(P25,P75)表示,组间比较采用Mann-Whitney U检验;c分类资料以率(%)及其(95% CI)值表示,组间比较采用χ2检验。 表 2 2017年―2018年南京成人居民主要慢性病危险因素关联性分析[OR(95% CI)]a
Table 2. The association of main chronic disease risk factors among adult residents in Nanjing from 2017 to 2018 [OR(95% CI)]a
危险因素 现在吸烟 有害饮酒 蔬菜水果摄入不足 身体活动不足 超重/肥胖 血压升高 FPG升高 血脂异常 现在吸烟 1.000 有害饮酒 3.848(3.573~4.162) b 1.000 蔬菜水果摄入不足 1.013(0.968~1.071) c 0.998(0.927~1.074) c 1.000 身体活动不足 1.015(0.973~1.074) c 1.082(1.001~1.146) b 1.313(1.257~1.361) b 1.000 超重/肥胖 1.142(1.088~1.186) b 1.566(1.472~1.666) b 0.988(0.953~1.017) c 1.055(1.022~1.103) b 1.000 血压升高 1.287(1.202~1.365) b 1.689(1.552~1.844) b 1.062(1.001~1.114) b 1.005(0.945~1.062) c 2.338(2.211~2.454) b 1.000 FPG升高 1.309(1.191~1.437) b 1.419(1.248~1.606) b 1.060(0.983~1.138) c 1.111(1.032~1.119) b 1.666(1.552~1.796) b 1.930(1.779~2.088) b 1.000 血脂异常 1.393(1.320~1.471) b 1.422(1.333~1.532) b 0.909(0.958~1.052) c 0.993(0.952~1.030) c 1.747(1.681~1.822) b 1.660(1.567~1.745) b 2.247(2.092~2.431) b 1.000 注:a所有OR值均调整年龄、性别、地区、受教育水平及职业类型协变量;bP < 0.01;c P>0.05。 表 3 2017年―2018年南京成人居民主要慢性病危险因素聚集情况及多水平模型分析
Table 3. Clustering of main chronic disease risk factors and analysis the association by multilevel model among adult residents in Nanjing from 2017 to 2018
特征 暴露情况[n(%)] a χ2值 P值 多水平模型分析[OR(95% CI)] b 0项 1项 2项 ≥3项 1项 2项 ≥3项 性别 5 264.578 < 0.001 女 6 458(21.22) 10 940(35.59) 7 793(25.61) 5 244(17.23) 1.000 1.000 1.000 男 2 640(8.84) 7 110(23.82) 7 985(26.74) 12 116(40.59) 1.602(1.516~1.694) 2.537(2.413~2.691) 5.788(5.481~6.127) 年龄组(岁) 4 827.126 < 0.001 18~<35 5 321(22.97) 8 670(37.43) 5 559(24.00) 3 612(15.59) 1.000 1.000 1.000 35~<60 2 945(11.53) 6 954(27.24) 7 001(27.42) 8 443(33.81) 1.298(1.214~1.388) 1.827(1.702~1.961) 2.930(2.716~3.161) ≥60 832(7.18) 2 426(20.93) 3 215(27.74) 5 116(44.15) 1.456(1.302~1.629) 2.412(2.153~2.702) 4.496(4.002~5.052) 地区 283.241 < 0.001 城区 6 248(16.10) 11 987(30.88) 10 239(26.38) 10 340(26.64) 1.000 1.000 1.000 郊县 2 850(13.27) 6 063(28.24) 5 536(25.79) 7 020(32.70) 1.157(1.089~1.229) 1.277(1.198 ~1.361) 1.691(1.582~1.807) 受教育水平 2 497.250 < 0.001 大专及以上 5 660(20.36) 9 751(34.94) 6 902(24.82) 5 528(19.88) 1.000 1.000 1.000 初中/高中 2 941(10.88) 7 010(25.94) 7 307(27.04) 9 762(36.13) 1.381(1.314~1.456) 2.054(1.938~2.172) 3.443(3.251~3.637) 小学及以下 497(9.11) 1 325(24.28) 1 566(28.69) 2 070(37.93) 1.552(1.389~1.725) 2.605(2.341~2.989) 4.269(3.840~4.752) 职业类型 2 333.346 < 0.001 蓝领人员 1 923(14.42) 3 710(27.82) 3 439(25.79) 4 262(31.96) 1.000 1.000 1.000 服务人员 1 185(16.48) 2 273(31.60) 1 877(26.10) 1 857(25.82) 1.103(1.007~1.209) 1.133(1.029~1.248) 1.121(1.014~1.239) 白领人员 3 380(17.42) 6 446(33.22) 4 932(25.41) 4 648(23.95) 1.155(1.072~1.244) 1.121(1.036~1.213) 1.084(0.998~1.177) 学生 1 014(26.44) 1 542(40.21) 919(23.96) 360(9.39) 1.038(0.925~1.164) 0.935(0.822~1.063) 0.478(0.407~0.560) 离退休人员 1 596(9.66) 4 079(24.70) 4 608(27.90) 6 233(37.74) 1.246(1.140~1.362) 1.442(1.316~1.579) 1.677(1.529~1.840) 婚姻状况 2 019.420 < 0.001 未婚 2 578(24.42) 3 986(37.76) 2 489(23.58) 1 503(14.24) 1.000 1.000 1.000 已婚/同居 6 297(13.25) 13 520(28.44) 12 676(26.67) 15 043(31.65) 1.173(1.087~1.267) 1.347(1.237~1.467) 1.607(1.460~1.769) 丧偶/离异/分居 223(10.18) 544(24.83) 610(27.84) 814(37.15) 1.183(0.991~1.411) 1.448(1.210~1.734) 1.946(1.617~2.341) 注:a暴露率均经复杂加权后计算;b本分析将慢性病危险因素聚集情况作为因变量,以0项危险因素作为参照组,即1项比0项,2项比0项,≥3项比0项,所有OR值均调整年龄、性别、地区、受教育水平及职业类型协变量,均有P<0.001。 -
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