Post-traumatic stress disorder prevalence and vulnerable groups after the outbreak of COVID-19 in Chinese adults
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摘要:
目的 评估中国COVID-19疫情暴发后创伤后应激障碍(post-traumatic stress disorder, PTSD)在年满18岁的成年人中流行情况,并探索源于该流行病的PTSD弱势群体。 方法 基于全国手机号段库通过随机数字拨号方法(random digital dialing, RDD)进行抽样,招募电话调查员,通过基于电脑辅助的电话调查方法(computer-assisted telephone interviewing, CATI)进行调查,自2020年5月11日-2020年5月28日共调查成功问卷4 206份,样本覆盖全国所有地(市)级单位。PTSD的测量采用创伤后应激障碍筛查量表第5版(post-traumatic stress disorder checklist 5th edition, PCL-5)进行。 结果 全国总的PTSD疑似阳性率为2.06%,武汉市、湖北省其他地区以及湖北省以外的其他省(区)PTSD疑似阳性率分别为2.88%、2.54%和2.03%。PTSD疑似阳性多因素Logistic回归分析模型分析显示,中年、居住地为农村及低社会阶层的人群PTSD疑似阳性率更高。 结论 COVID-19相关的PTSD发生率相对较低,但因为中国的人口基数大,仍然需要引起重视;在进行COVID-19相关的PTSD预防和控制时,需要更多地考虑社会与经济地位上弱势的群体。 Abstract:Objective To evaluate post-traumatic stress disorder (PTSD) prevalence after the outbreak of COVID-19 in Chinese adults and to explore the vulnerable groups of COVID-19-associated PTSD. Methods Random digital dialling sampling method was used based on the national cell phone segment database. Computer assisted telephone interviewing platform was administered to collect 4 206 questionnaires from all prefecture-level cities in China from May 11th to 28th 2020. PTSD score was evaluated with the post-traumatic stress disorder checklist 5th edition (PCL-5). Results The total national suspected PTSD rate was 2.06%. The suspected PTSD rate for Wuhan City, other areas in Hubei and other Provinces were 2.88%, 2.54% and 2.03% respectively. The multivariate Logistic regression model showed that middle age, rural location, and lower social-economic status was positively associated with suspected PTSD. Conclusions Although the COVID-19-associated PTSD rate was relatively low, more attention should be paid because of the largest population in China. And more consideration should be given to the low SES population for the control and prevention of COVID-19-associated PTSD. -
表 1 PTSD分值和疑似阳性率在不同特征人群分布情况
Table 1. The distribution of PTSD scores and suspected positive rates by different characteristic population
变量 总人数(N) PTSD分值 PTSD疑似阳性率(%) x s Z/χ2值 P值 发生率(%) χ2值 P值 性别 -3.340 <0.001 0.398 0.528 男性 2 617 6.80 7.86 1.59 女性 1 589 7.21 7.38 1.85 年龄(岁) 37.722 <0.001 13.010 0.005 18~ < 30 1 441 6.04 6.36 0.91 30~ < 45 1 617 6.76 7.65 1.81 45~ < 60 800 8.42 9.03 2.93 ≥60 348 8.39 8.79 2.35 教育程度 77.494 <0.001 19.733 <0.001 初中及以下 754 9.11 9.77 3.38 高中/中专/技校 864 7.97 8.40 2.36 大专及以上 2 588 6.00 6.50 1.09 城乡 -3.475 <0.001 9.878 0.002 城市 3 227 6.61 7.17 1.41 农村 963 8.10 9.13 2.94 社会阶层 78.348 <0.001 63.871 <0.001 下层 364 10.04 11.05 6.67 中下层 1 087 7.96 7.93 2.24 中层 2 374 6.24 6.90 0.89 中上层 345 5.49 6.27 0.88 地区 39.391 <0.001 0.890 0.641 武汉市 1 304 7.65 7.71 1.94 湖北省其他地区 1 064 7.26 8.17 1.91 其他省(区) 1 838 6.30 7.41 1.54 SARS-CoV-2暴露 -4.850 <0.001 2.019 0.155 否 4 128 6.88 7.62 1.71 是 78 10.72 9.84 3.85 家人确诊COVID-19 -1.905 0.057 0.885 0.347 否 4 156 6.94 7.69 1.77 是 50 8.16 7.00 0.00 家人因COVID-19集中隔离或收治 -3.710 <0.001 2.575 0.109 否 4 099 6.90 7.67 1.70 是 107 9.04 8.08 3.77 所在村或社区有确诊COVID-19 -5.790 <0.001 1.572 0.210 否 2 822 6.54 7.34 1.58 是 1 384 7.81 8.28 2.12 表 2 PTSD分值及PTSD疑似阳性率的多因素回归分析
Table 2. Multivariate regression analysis on PTSD score and suspected positive rate
变量 PTSD分值(OLS回归分析模型) PTSD疑似阳性(Firth Logistic回归分析模型) 性别 男性 1.000 1.000 女性 0.829 a 1.020 年龄(岁) 18~ < 30 1.000 1.000 30~ < 45 0.262 1.811 45~ < 60 1.245 a 2.251 a ≥60 1.290 b 2.151 教育程度 初中及以下 1.000 1.000 高中/中专/技校 -0.674 0.994 大专及以上 -2.083 a 0.701 城乡 城市 1.000 1.000 农村 1.041 a 1.743 c 社会阶层 下层 1.000 1.000 中下层 -1.481 a 0.388 b 中层 -2.843 a 0.169 a 中上层 -3.379 a 0.196 b 地区 武汉市(参照组) 1.000 1.000 湖北省其他地区 -0.113 1.042 其他省(区) -0.793 c 0.986 SARS-CoV-2暴露 否 1.000 1.000 是 3.514 a 2.299 家人确诊COVID-19 否 1.000 1.000 是 -0.765 0.162 家人因COVID-19集中隔离或收治 否 1.000 1.000 是 1.136 3.051 所在村或社区有确诊COVID-19 否 1.000 1.000 是 1.424 a 1.741 截距项 7.605 a 0.017 c 注:aP < 0.001;bP < 0.01;cP < 0.05。 -
[1] Wang C, Pan R, Wan X, et al. A longitudinal study on the mental health of general population during the COVID-19 epidemic in China[J]. Brain Behav Immun, 2020, 87: 40-48. DOI: 10.1016/j.bbi.2020.04.028. [2] Bo HX, Li W, Yang Y, et al. Posttraumatic stress symptoms and attitude toward crisis mental health services among clinically stable patients with COVID-19 in China[J]. Psychol Med, 2021, 51(6): 1052-1053. DOI: 10.1017/S0033291720000999. [3] Lai J, Ma S, Wang Y, et al. Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019[J]. JAMA Netw Open, 2020, 3(3): e203976. DOI: 10.1001/jamanetworkopen.2020.3976. [4] Tang W, Hu T, Hu B, et al. Prevalence and correlates of PTSD and depressive symptoms one month after the outbreak of the COVID-19 epidemic in a sample of home-quarantined Chinese university students[J]. J Affect Disord, 2020, 274: 1-7. DOI: 10.1016/j.jad.2020.05.009. [5] Zhang Y, Ma ZF. Impact of the COVID-19 pandemic on mental health and quality of life among local residents in Liaoning Province, China: A Cross-Sectional Study[J]. Int J Environ Res Public Health, 2020, 17(7): 2381. DOI: 10.3390/ijerph17072381. [6] Blevins CA, Weathers FW, Davis M T, et al. The posttraumatic stress disorder checklist for DSM-5 (PCL-5): development and initial psychometric evaluation[J]. J Trauma Stress, 2015, 28(6): 489-498. DOI: 10.1002/jts.22059. [7] Liu N, Zhang F, Wei C, et al. Prevalence and predictors of PTSS during COVID-19 Outbreak in China Hardest-hit Areas: Gender differences matter[J]. Psychiatry Res, 2020, 287: 112921. DOI: 10.1016/j.psychres.2020.112921. [8] Liang L, Gao T, Ren H, et al. Post-traumatic stress disorder and psychological distress in Chinese youths following the COVID-19 emergency[J]. J Health Psychol, 2020, 25(9): 1164-1175. DOI: 10.1177/1359105320937057. [9] Qiu J, Shen B, Zhao M, et al. A nationwide survey of psychological distress among Chinese people in the COVID-19 epidemic: implications and policy recommendations[J]. Gen Psychiatr, 2020, 33(2): e100213. DOI: 10.1136/gpsych-2020-100213. [10] Mclean CP, Anderson ER. Brave men and timid women? A review of the gender differences in fear and anxiety[J]. Clin Psychol Rev, 2009, 29(6): 496-505. DOI: 10.1016/j.cpr.2009.05.003. [11] Soni M, Curran VH, Kamboj SK. Identification of a narrow post-ovulatory window of vulnerability to distressing involuntary memories in healthy women[J]. Neurobiol Learn and Mem, 2013, 104(1): 32-38. DOI: 10.1016/j.nlm.2013.04.003. [12] Clara GS, Berta A, Miguel AC, et al. Mental health consequences during the initial stage of the 2020 Coronavirus pandemic (COVID-19) in Spain[J]. Brain Behav Immun, 2020, 87: 172-176. DOI: 10.1016/j.bbi.2020.05.040. [13] 中国疾病预防控制中心新型冠状病毒肺炎应急响应机制流行病学组. 新型冠状病毒肺炎流行病学特征分析[J]. 中华流行病学杂志, 2020, 41(2): 145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003.Epidemiology Working Group for NCIP Epidemic Response. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China[J]. Chin J Epidemiol, 2020, 41(2): 145-151. DOI: 10.3760/cma.j.issn.0254-6450.2020.02.003. [14] Boyraz G, Legros DN. Coronavirus Disease (COVID-19) and Traumatic Stress: Probable Risk Factors and Correlates of Posttraumatic Stress Disorder[J]. J Loss Trauma, 2020(1): 1-20. DOI:https://doi.org/ 10.1080/15325024.2020.1763556.