-
摘要: 精准营养是基于遗传、生理代谢、生活特征、环境暴露等因素提出的“量体裁衣”的膳食措施。精准营养并非是为每个个体研发与其他所有个体不同的营养处方,而是更需要从群体、亚群体维度探讨精准营养的膳食措施,达到促进健康和降低慢性病风险的目的。Abstract: Precision nutrition is a "tailored" dietary measure based on genetics, physiological metabolism, living characteristics, environmental exposure and other factors. Precision nutrition does not favor that each person or patient will be treated dietary measures differently from every other individual. The mission of precision nutrition should also emphasize to develop dietary measures from the group and subgroup dimensions to promote health and reduce the risk of chronic diseases.
-
Key words:
- Precision nutrition /
- Groups and subgroups /
- Chronic disease risk
-
[1] Schork NJ. Personalized medicine: time for one-person trials[J]. Nature, 2015, 520(7549): 609-611. DOI: 10.1038/520609a. [2] de Toro-Martín J, Arsenault BJ, Després JP, et al. Precision nutrition: a review of personalized nutritional approaches for the prevention and management of metabolic syndrome[J]. Nutrients, 2017, 9(8): 913. DOI: 10.3390/nu9080913. [3] National Academies of Sciences, Engineering and Medicine, Health and Medicine Division, et al. Challenges and opportunities for precision and personalized nutrition: proceedings of a workshop[M]. Washington (DC): National Academies Press (US), 2022: 3-8. [4] Ordovas JM, Ferguson LR, Tai ES, et al. Personalised nutrition and health[J]. BMJ, 2018, 361: bmj. k2173. DOI: 10.1136/bmj.k2173. [5] National Research Council (US) Committee on A Framework for Developing a New Taxonomy of Disease. Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease[M]. Washington (DC): National Academies Press (US), 2011: 12-13. [6] Zeisel SH. Precision (Personalized) nutrition: understanding metabolic heterogeneity[J]. Annu Rev Food Sci Technol, 2020, 11: 71-92. DOI: 10.1146/annurev-food-032519-051736. [7] 中国营养学会. 中国居民膳食营养素参考摄入量(2013)[M]. 北京: 科学出版社, 2014: 323.Chinese Nutrition Society. Chinese Dietary Reference Intakes(2013)[M]. Beijing: Science Press, 2014: 323. [8] 中国营养学会. 中国居民膳食指南(2022)[M]. 北京: 人民卫生出版社, 2022: 265-266.Chinese Nutrition Society. Dietary guidelines for Chinese residents (2022)[M]. Beijing: People's Medical Publishing House, 2022: 265-266. [9] Seidelmann SB, Claggett B, Cheng S, et al. Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis[J]. Lancet Public Health, 2018, 3(9): e419-e428. DOI: 10.1016/S2468-2667(18)30135-X. [10] AlAufi NS, Chan YM, Waly MI, et al. Application of mediterranean diet in cardiovascular diseases and type 2 diabetes mellitus: motivations and challenges[J]. Nutrients, 2022, 14(13): 2777. DOI: 10.3390/nu14132777. [11] Martínez-González MA, Salas-Salvadó J, Estruch R, et al. Benefits of the mediterranean diet: insights from the predimed study[J]. Prog Cardiovasc Dis, 2015, 58(1): 50-60. DOI: 10.1016/j.pcad.2015.04.003. [12] Heianza Y, Qi L. Gene-diet interaction and precision nutrition in obesity[J]. Int J Mol Sci, 2017, 18(4): 787. DOI: 10.3390/ijms18040787. [13] Zhao M, Wang X, He M, et al. Homocysteine and stroke risk: modifying effect of methylenetetrahydrofolate reductase C677T polymorphism and folic acid intervention[J]. Stroke, 2017, 48(5): 1183-1190. DOI: 10.1161/STROKEAHA.116.015324. [14] Wall TL, Luczak SE, Hiller-Sturmhöfel S. Biology, genetics, and environment: underlying factors influencing alcohol metabolism[J]. Alcohol Res, 2016, 38(1): 59-68. [15] Lynch SV, Pedersen O. The human intestinal microbiome in health and disease[J]. N Engl J Med, 2016, 375(24): 2369-2379. DOI: 10.1056/NEJMra1600266. [16] Fan Y, Pedersen O. Gut microbiota in human metabolic health and disease[J]. Nat Rev Microbiol, 2021, 19(1): 55-71. DOI: 10.1038/s41579-020-0433-9. [17] Zivkovic AM, Rucker RB. Gut microbiota - nutrition and health[J]. Nutr Res, 2022, 100: 42-46. DOI: 10.1016/j.nutres.2021.12.005. [18] Li D, Lu Y, Yuan S, et al. Gut microbiota-derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis[J]. Am J Clin Nutr, 2022, 116(1): 230-243. DOI: 10.1093/ajcn/nqac074. [19] Witkowski M, Weeks TL, Hazen SL. Gut microbiota and cardiovascular disease[J]. Circ Res, 2020, 127(4): 553-570. DOI: 10.1161/CIRCRESAHA.120.316242. [20] Xue H, Chen X, Yu C, et al. Gut microbially produced indole-3-propionic acid inhibits atherosclerosis by promoting reverse cholesterol transport and its deficiency is causally related to atherosclerotic cardiovascular disease[J]. Circ Res, 2022, 131(5): 404-420. DOI: 10.1161/CIRCRESAHA.122.321253. [21] Fava F, Rizzetto L, Tuohy KM. Gut microbiota and health: connecting actors across the metabolic system[J]. Proc Nutr Soc, 2019, 78(2): 177-188. DOI: 10.1017/S0029665118002719. [22] Megur A, Daliri EB, Baltriukienè D, et al. Prebiotics as a tool for the prevention and treatment of obesity and diabetes: classification and ability to modulate the gut microbiota[J]. Int J Mol Sci, 2022, 23(11): 6097. DOI: 10.3390/ijms23116097. [23] Bashiardes S, Godneva A, Elinav E, et al. Towards utilization of the human genome and microbiome for personalized nutrition[J]. Curr Opin Biotechnol, 2018, 51: 57-63. DOI: 10.1016/j.copbio.2017.11.013.
点击查看大图
计量
- 文章访问数: 343
- HTML全文浏览量: 253
- PDF下载量: 77
- 被引次数: 0