2014-2019年武汉市居民宫颈癌死亡特征及潜在减寿年数

张晓霞; 田卫东; 赵原原; 杨念念; 代娟; 金琦曼; 严亚琼

doi:10.16462/j.cnki.zhjbkz.2023.01.021

2014-2019年武汉市居民宫颈癌死亡特征及潜在减寿年数

doi: 10.16462/j.cnki.zhjbkz.2023.01.021

1.
430024 武汉，武汉市疾病预防控制中心慢性非传染性疾病防制所
2.
430200 武汉，江夏区疾病预防控制中心

基金项目:

武汉市科技基金资助项目 2015061701011631

详细信息

通讯作者:
严亚琼，E-mail: 89519752@qq.com

中图分类号: R737.33
计量
- 文章访问数: 251
- HTML全文浏览量: 159
- PDF下载量: 31
- 被引次数: 0
出版历程
- 收稿日期: 2021-06-25
- 修回日期: 2021-12-23
- 网络出版日期: 2023-02-09
- 刊出日期: 2023-01-10

Analysis of death characteristics and potential years of life lost of cervical cancer in Wuhan residents from 2014 to 2019

1.
Chronic Disease Prevention and Control, Wuhan Municipal Center for Disease Control and Prevention, Wuhan 430024, China
2.
Jiangxia District Center for Disease Control and Prevention, Wuhan 430200, China

Funds:

Science and Technology Fund Project of Wuhan 2015061701011631

More Information

Corresponding author: YAN Ya-qiong, E-mail: 89519752@qq.com

摘要

摘要: 目的了解2014-2019年武汉市居民宫颈癌死亡流行特征及潜在减寿年数(potential years of life lost, PYLL)，为宫颈癌防制提供数据支持。方法利用武汉市死因监测系统收集2014-2019年武汉市居民宫颈癌死亡情况，计算武汉市居民不同年龄、地区之间宫颈癌粗死亡率及标化死亡率的变化趋势，并测算由宫颈癌导致的潜在减寿年数并分析宫颈癌流行病学特征。结果武汉市宫颈癌粗死亡率由2014年的0.60/10万上升至2019年的2.13/10万，年度变化百分比(annual percentage change, APC)为32.63%，变化趋势差异有统计学意义(t=-3.05, P=0.038)。随着年龄增长，武汉市宫颈癌死亡率呈现波动上升趋势。由宫颈癌导致的潜在减寿年数由2014年的640.00人年升高至2019年的2 660.00人年。2014-2019年的PYLL为15.26年，标化潜在减寿率为0.23‰。结论 2014-2019年武汉市居民宫颈癌死亡率呈上升趋势，应积极针对中低年龄段已婚女性开展宫颈癌筛查，加强宫颈癌防制措施，降低宫颈癌导致的疾病负担。
- 宫颈癌 /
- 死亡率 /
- 潜在减寿年数
Abstract: Objective To investigate the prevalence characteristics and the potential years of life lost (PYLL) of cervical cancer in Wuhan from 2014 to 2019, and to provide a scientific basis for prevention and control. Methods The Cervical cancer deaths among Wuhan residents during 2014-2019 were collected from the population-based Mortality Surveillance System. We analyzed the change tendency of crude and standardized mortality rate of cervical cancer in different area and age groups. And PYLL was also calculated to describe the epidemiological characteristics of cervical cancer. Results The crude mortalities of cervical cancer was increased from 0.60/10⁵ in 2014 to 2.13/10⁵ in 2019, with APC equal to 32.63% (t=-3.05, P=0.038). The mortality rate of cervical cancer showed an upward trend with the increaseing age groups. The PYLL of cervical cancer increased from 640.00 person-years in 2014 to 2 660.00 person-years in 2019. The average PYLL caused by cervical cancer was 15.26 years, and the standardized PYLL rate was 0.23‰. Conclusions The mortality rate of cervical cancer presented an upward trend with the increasing age. Cervical cancer screening should be promoted in younger women. It is necessary to take the corresponding preventive and control measures for reducing the burden of disease.
- Cervical cancer /
- Mortality rate /
- Potential years of life lost

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表 1 2014-2019年武汉市分城乡宫颈癌死亡率

Table 1. The mortality of cervical cancer in Wuhan from 2014 to 2019

年份(年)	合计		中心城区		远城区		χ²值^a	P值^a
年份(年)	宫颈癌死亡粗率(/10万)	宫颈癌死亡标化率(/10万)	宫颈癌死亡粗率(/10万)	宫颈癌死亡标化率(/10万)	宫颈癌死亡粗率(/10万)	宫颈癌死亡标化率(/10万)	χ²值^a	P值^a
2014	0.60	0.47	0.50	0.34	0.73	0.68	11.391	0.001
2015	0.74	0.63	0.76	0.61	0.72	0.67	0.283	0.595
2016	2.11	1.61	2.31	1.59	1.88	1.65	0.113	0.737
2017	2.43	1.88	2.50	1.75	2.35	2.04	2.262	0.133
2018	2.31	1.79	2.45	1.72	2.13	1.87	0.683	0.424
2019	2.13	1.64	2.21	1.60	2.03	1.77	0.872	0.350
APC(%)	32.63	31.27	37.15	36.91	27.90	26.03
t值	-3.05	3.12	3.00	-3.11	-3.00	-3.00
P值	0.038	0.035	0.040	0.036	0.040	0.040
注：^a标化率比较的统计分析结果。

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表 2 2014-2019年武汉市宫颈癌年龄别死亡率及构成比

Table 2. The mortality and proportion of cervical cancer by age in Wuhan from 2014 to 2019

年龄组(岁)	死亡例数(人)	死亡率(/10万)	构成比(%)
＜25	0	0.00	0.00
25~＜30	5	0.11	0.58
30~＜35	10	0.22	1.16
35~＜40	23	0.61	2.67
40~＜45	44	1.19	5.10
45~＜50	98	2.35	11.37
50~＜55	132	3.18	15.31
55~＜60	126	3.50	14.62
60~＜65	97	2.82	11.25
65~＜70	97	3.90	11.25
70~＜75	68	4.34	7.90
75~＜80	77	6.57	8.93
80~＜85	53	6.48	6.15
≥85	32	5.97	3.71
合计	862	1.73	100.00

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表 3 2014-2019年武汉市宫颈癌PYLL分析

Table 3. Analysis of PYLL about cervical cancer in Wuhan from 2014 to 2019

年份(年)	PYLL (人年)	潜在减寿率(‰)	平均减寿年数(年)	标化潜在减寿年数(人年)	标化潜在减寿率(‰)
2014	640.00	0.08	13.33	556.53	0.07
2015	1 022.50	0.13	17.33	989.82	0.12
2016	2 532.50	0.32	15.27	2 141.87	0.26
2017	2 945.00	0.38	15.75	2 636.54	0.32
2018	2 897.50	0.35	15.50	2 587.91	0.31
2019	2 660.00	0.30	14.38	2 364.60	0.27
合计	12 697.50	0.26	15.26	11 277.26	0.23

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参考文献(15)

[1]	Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249. DOI: 10.3322/caac.21660.
[2]	Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012[J]. Int J Cancer, 2015, 136(5): E359-E386. DOI: 10.1002/ijc.29210.
[3]	魏长慧, 朱继存, 牛媛娜, 等. 2004-2016年中国女性生殖系统恶性肿瘤死亡趋势分析[J]. 中华疾病控制杂志, 2019, 23(5): 506-511. DOI: 10.16462/j.cnki.zhjbkz.2019.05.003. Wei CH, Zhu JC, Niu YN, et al. Analysis of the mortality trend of female reproductive system cancer in China from 2004 to 2016[J]. Chin J Dis Control Prev, 2019, 23(5): 506-511. DOI: 10.16462/j.cnki.zhjbkz.2019.05.003.
[4]	文莉, 张波, 易念华. 2005~2012年武汉市妇科癌症患病趋势及危险因素分析[J]. 检验医学与临床, 2014, 11(16): 2218-2219. DOI: 10.3969/j.issn.1672-9455.2014.16.011. Wen L, Zhang B, Yi NH. Study of prevalence trends and risk factors of gynecologic cancer in Wuhan from 2005 to 2012[J]. Lab Med Clin, 2014, 11(16): 2218-2219. DOI: 10.3969/j.issn.1672-9455.2014.16.011.
[5]	周薇, 张志将, 王丽君, 等. 中国子宫颈癌1987-2014年死亡趋势的Joinpoint回归分析[J]. 中国癌症杂志, 2017, 27(8): 634-640. DOI: 10.19401/j.cnki.1007-3639.2017.08.006. Zhou W, Zhang ZJ, Wang LJ, et al. Joinpoint regression analysis for the trends of cervical cancer mortality between 1987-2014 in China[J]. Chin Oncol, 2017, 27(8): 634-640. DOI: 10.19401/j.cnki.1007-3639.2017.08.006.
[6]	鲁爱枝, 张敏, 王金融, 等. 湖北省肿瘤登记地区2012年宫颈癌发病及死亡分析[J]. 肿瘤防治研究, 2018, 45(1): 32-36. DOI: 10.3971/j.issn.1000-8578.2018.17.0749. Lu AZ, Zhang M, Wang JR, et al. Incidence and mortality of cervical cancer in cancer registries areas of Hubei Province, 2012[J]. Cancer Res Prev Treat, 2018, 45(1): 32-36. DOI: 10.3971/j.issn.1000-8578.2018.17.0749.
[7]	项永兵, 张薇, 高立峰, 等. 恶性肿瘤发病率的时间趋势分析方法[J]. 中华流行病学杂志, 2004, 25(2): 173-177. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHLX200402028.htm Xiang YB, Zhang W, Gao LF, et al. Methods for time trend analysis of cancer incidence rates[J]. Chin J Epidemiol, 2004, 25(2): 173-177. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHLX200402028.htm
[8]	蔡玥. 世界和中国人均期望寿命变化规律[J]. 中国卫生信息管理杂志, 2012, 9(5): 77-81. DOI: 10.3969/j/issn.1672-5166.2012.05.017. Cai Y. Changes of life expectancy in the world and in China[J]. Chinese Journal of Health Informatics and Management, 2012, 9(5): 77-81. DOI: 10.3969/j/issn.1672-5166.2012.05.017.
[9]	周琦, 吴小华, 刘继红, 等. 宫颈癌诊断与治疗指南(第四版)[J]. 中国实用妇科与产科杂志, 2018, 34(6): 613-622. DOI: 10.19538/j.fk2018060111. Zhou Q, Wu XH, Liu JH, et al. Guidelines for diagnosis and Treatment of Cervical Cancer (4th Edition)[J]. Chin J Pract Gynecol Obstetr, 2018, 34(6): 613-622. DOI: 10.19538/j.fk2018060111.
[10]	丁波, 孙玮, 沈杨, 等. TNF-α基因rs1800629多态性与中国人群宫颈癌的易感性[J]. 中华疾病控制杂志, 2019, 23(7): 850-855. DOI: 10.16462/j.cnki.zhjbkz.2019.07.021. Ding B, Sun W, Shen Y, et al. TNF-α rs1800629 polymorphisms in the genetic susceptibility to cervical cancer[J]. Chin J Dis Control Prev, 2019, 23(7): 850-855. DOI: 10.16462/j.cnki.zhjbkz.2019.07.021.
[11]	朱琳, 王灵, 丁一波, 等. 1974-2015年上海市杨浦区宫颈癌死亡趋势分析[J]. 上海预防医学, 2018, 30(2): 97-100. DOI: 10.19428/j.cnki.sjpm.2018.18557. Zhu L, Wang L, Ding YB, et al. Mortality trend analysis on cervical carcinoma in Yangpu District of Shanghai during 1974-2015[J]. Shanghai Journal of Preventive Medicine, 2018, 30(2): 97-100. DOI: 10.19428/j.cnki.sjpm.2018.18557.
[12]	向芳, 李胜, 郝莲, 等. 2003-2017年中国女性宫颈癌死亡趋势分析——基于年龄-时期-队列模型[J]. 卫生经济研究, 2020, 37(5): 23-27. DOI: 10.14055/j.cnki.33-1056/f.2020.05.024. Xiang F, Li S, He L, et al. Analysis on Chinese women's cervical cancer death trends from 2003 to 2017--based on age-period-cohort model[J]. Health Economics Research, 2020, 37(5): 23-27. DOI: 10.14055/j.cnki.33-1056/f.2020.05.024.
[13]	王晶. 妇女宫颈癌认知、态度、行为调查以及健康教育效果评估[D]. 武汉: 华中科技大学, 2018. Wang J. Survey on the status of the cognition, attitude and practice related to cervical cancer among women and evaluate the impact of health education programme[D]. Wuhan: Huazhong University of Science and Technology, 2018.
[14]	彭娟霞, 李燕, 马小红, 等. 2011-2015年银川市四种常见妇科恶性肿瘤死亡及减寿分析[J]. 宁夏医科大学学报, 2019, 41(3): 254-258, 267. DOI: 10.16050/j.cnki.issn1674-6309.2019.03.008. Peng JX, Li Y, Ma XH, et al. Analysis of death and life loss of four common gynecological malignant tumors in Yinchuan City from 2011 to 2015[J]. J Ningxia Med Univ, 2019, 41(3): 254-258, 267. DOI: 10.16050/j.cnki.issn1674-6309.2019.03.008.
[15]	黄霜, 胡劲松, 黄渊秀, 等. 2014-2016年长沙市居民恶性肿瘤死亡率和潜在减寿分析[J]. 中国慢性病预防与控制, 2019, 27(2): 158-161. DOI: 10.16386/j.cjpccd.issn.1004-6194.2019.02.021. Huang S, Hu JS, Huang YX, et al. Analysis of mortality and potension years of life lost of malignant tumor in Changsha, 2014-2016[J]. Chin J Prev Contr Chron Dis, 2019, 27(2): 158-161. DOI: 10.16386/j.cjpccd.issn.1004-6194.2019.02.021.