Comorbidity patterns and conditions among 84 724 cerebral infarction patients in Gansu Province
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摘要:
目的 分析甘肃省脑梗死病例慢性病的共病情况和组合模式,为脑梗死共病防治提供依据。 方法 纳入2020年1月1日―2020年12月31日甘肃省14个市州公立医院脑梗死出院病例84 724例,对其基本人口学特征及共病史进行描述性分析,用UpSet集合图分析共病组合模式。 结果 84 724例脑梗死病例中,男性占54.06%,病例年龄为(67.65±10.83)岁,60~ < 80岁病例最多,占65.51%;80.23%的脑梗死病例存在共病,共患1~2种慢性病占59.32%,共患2种以上的病例占20.91%;共病率最高的慢性病是高血压(53.69%);一元共病组合中最常见的是脑梗死+高血压(17.40%),二元共病组合中最常见的是脑梗死+高血压+心脏病(7.04%),三元共病组合中最常见的是脑梗死+高血压+心脏病+慢性肺部疾患(1.77%)。 结论 甘肃省脑梗死病例共病患病率较高,高血压是脑梗死共病风险最高的慢性病,建议卫生部门加强脑梗死共患慢性病的疾病管理。 Abstract:Objective The aim of this study is to investigate the comorbidity conditions and patterns among discharged cerebral infarction patients in Gansu Province, providing a basis for the prevention and treatment of comorbidities related to cerebral infarction. Methods A total of 84 724 patients with cerebral infarction from 14 public hospitals in Gansu Province were enrolled between January 1, 2020, and December 31, 2020. Basic demographic characteristics and comorbidities history were descriptively analyzed, and the comorbidity models were examined using UpSet graph. Results Of the 84 724 cerebral infarction patients, 54.06% were male. The average age of patients was (67.65±10.83) years, with the majority of patients (65.51%) aged between 60 and 80 years. The prevalence of comorbidity was 80.23%, with 59.32% of patients presenting with one or two chronic diseases and 20.91% with more than two. Hypertension was the most common comorbid chronic disease (53.69%). The most prevalent singular comorbidity model was cerebral infarction and hypertension (17.40%), the most common binary model was cerebral infarction, hypertension, and heart disease (7.04%), and the most frequent ternary comorbidity model was cerebral infarction, hypertension, heart disease, and chronic lung disease (1.77%). Conclusions The prevalence of comorbidity among cerebral infarction patients in Gansu Province was relatively high, with hypertension being the most common comorbidity. Health-relevant departments should focus on strengthening the management of chronic diseases associated with cerebral infarction. -
Key words:
- Cerebral infarction /
- Comorbidity /
- Comorbidity model
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表 1 脑梗死病例的基本特征
Table 1. Baseline characteristics of patients with cerebral infarction
变量 例数(n) 百分比(%) 性别 男 45 804 54.06 女 38 920 45.94 民族 汉族 80 069 94.51 其他民族 4 655 5.49 年龄组(岁) 12~ < 40 1 108 1.31 40~ < 60 19 563 23.09 60~ < 80 55 504 65.51 ≥80 8 549 10.09 婚姻状况 未婚 923 1.09 已婚 66 743 78.78 离异/丧偶 17 058 20.13 共患慢性病数量(个) 0 16 746 19.77 1 26 555 31.34 2 23 710 27.98 3 12 698 14.99 ≥4 5 015 5.92 表 2 2020年甘肃省脑梗死共病病例的地区分布[n(%)]
Table 2. The regional distribution graph of cerebral infarction patients with comorbidity in Gansu Province in 2020 [n(%)]
地区 非“共病”脑梗死患者 “共病”脑梗死患者 合计 兰州市 4 526(5.34) 16 078(18.98) 20 604(24.32) 张掖市 2 233(2.64) 9 842(11.61) 12 075(14.25) 庆阳市 1 643(1.94) 9 857(11.63) 11 500(13.57) 天水市 1 915(2.26) 8 762(10.34) 10 677(12.60) 平凉市 1 963(2.32) 8 418(9.94) 10 381(12.25) 酒泉市 1 037(1.22) 3 770(4.45) 4 807(5.67) 武威市 991(1.17) 3 066(3.62) 4 057(4.79) 定西市 648(0.76) 2 398(2.83) 3 046(3.60) 陇南市 637(0.75) 1 725(2.04) 2 362(2.79) 白银市 474(0.56) 1 729(2.04) 2 203(2.60) 临夏回族自治州 389(0.46) 1 121(1.32) 1 510(1.78) 金昌市 100(0.12) 616(0.73) 716(0.85) 甘南藏族自治州 107(0.13) 342(0.40) 449(0.53) 嘉峪关市 83(0.10) 254(0.30) 337(0.40) 合计 16 746(19.77) 67 978(80.23) 84 724(100.00) 表 3 不同性别脑梗死病例慢性病共病情况[n(%)]
Table 3. The characteristics of comorbidity for cerebral infarction patients in different genders [n(%)]
共患慢性病 总人数(N=84 724) 男性脑梗死病例(n=45 804) 女性脑梗死病例(n=38 920) $\chi$2值 P值 高血压 45 491(53.69) 24 691(53.91) 20 800(53.44) 1.796 0.180 心脏病 25 661(30.29) 13 606(29.70) 12 055(30.97) 16.047 < 0.001 慢性肺部疾患 12 497(14.75) 6 800(14.85) 5 697(14.64) 0.725 0.395 糖尿病 12 145(14.33) 6 710(14.65) 5 435(13.96) 8.046 0.005 肝脏疾病 7 382(8.71) 4 068(8.88) 3 314(8.51) 3.552 0.059 胃部或消化系统疾病 7 079(8.36) 3 662(7.99) 3 417(8.78) 16.916 < 0.001 血脂异常 6 945(8.20) 3 629(7.92) 3 316(8.52) 9.971 0.002 肾脏疾病 6 363(7.51) 3 561(7.77) 2 802(7.20) 10.017 0.002 情感和精神障碍 3 277(3.87) 1 655(3.61) 1 622(4.17) 17.387 < 0.001 肿瘤 3 056(3.61) 1 717(3.75) 1 339(3.44) 5.748 0.017 与记忆相关疾病 1 609(1.90) 907(1.98) 702(1.80) 3.517 0.061 关节炎或风湿病 1 349(1.59) 700(1.53) 649(1.67) 2.605 0.107 哮喘 403(0.48) 233(0.51) 170(0.44) 2.297 0.130 -
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