福建省8~10岁儿童不同甲状腺容积校正指数结果比较

王木华; 季淑眯; 陈迪群; 陈志辉

doi:10.16462/j.cnki.zhjbkz.2023.09.004

福建省8~10岁儿童不同甲状腺容积校正指数结果比较

doi: 10.16462/j.cnki.zhjbkz.2023.09.004

福建省疾病预防控制中心地方病及慢性非传染性疾病防治所，福州 350012

基金项目:

福建省卫生健康科技计划项目 2020CXA020

福建省科技创新平台建设项目 2019Y2001

详细信息

通讯作者:
陈志辉，E-mail：18906913056@163.com

中图分类号: R153.2;R181.2
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出版历程
- 收稿日期: 2022-08-04
- 修回日期: 2022-12-16
- 网络出版日期: 2023-10-12
- 刊出日期: 2023-09-10

Comparative of the results of different thyroid volume correction indexes for children aged 8-10 in Fujian Province

Institute for the Control and Prevention of Endemic and Chronic Non-communicabie Diseases, Fujian Provincial Center for Disease Control and Prevention, Fuzhou 350012, China

Funds:

Fujian Provincial Health Science and Technology Project 2020CXA020

Fujian Science and Technology Innovation Platform Construction Project 2019Y2001

More Information

Corresponding author: CHEN Zhihui, E-mail: 18906913056@163.com

摘要

摘要: 目的分析福建省8~10岁儿童甲状腺容积与体格发育的关系，探索适宜儿童甲状腺容积的校正方法。方法 2020-2021年采用多阶段分层整群随机抽样方法，抽取福建省3 732名8~10岁儿童。采用B超法检测其甲状腺容积，并测定其尿碘、食用盐碘含量。采用身高容积指数(height volume index, HVI)、体重身高容积指数(weight height volume index, WHVI)、体质容积指数(body mass volume index, BMIV)、体表面积容积指数(body surface volume index, BSAV)对甲状腺容积进行校正。结果 HVI校正后甲状腺容积与年龄、身高、体重、BMI、体表面积(body surface area, BSA)差异均有统计学意义，呈正相关(均P<0001)，且与原始甲状腺容积的相关性最强(r=0.918)，其次是BSAV(r=0.884)。但BSAV不受体重的影响，具有更好的适应性。结论建议使用BSAV法作为儿童甲状腺容积的校正法。
- 儿童 /
- 甲状腺容积 /
- 体格检查 /
- 校正指数
Abstract: Objective We aimed to analyze the relationship between thyroid volume and physical development in children aged 8-10 years, and to explore the suitable correction method for thyroid volume in children. Methods During 2020-2021, 3 732 children aged 8-10 years in Fujian Province were selected using the multi-stage stratified cluster random sampling method. The thyroid volume was evaluated using the B-ultrasonic method, and urinary iodine levels along with the iodine content in their diet were measured. Correction of thyroid volumes was done using height volume index (HVI), weight height volume index (WHVI), body mass volume index (BMIV), and body surface volume index (BSAV). Results There was a statistically significant association between thyroid volume and age, height, weight, BMI and BSAV after HVI correction (all P<0.001). The HVI corrected thyroid volume had the strongest correlation with the original thyroid volume (r=0.918), followed by the BSAV (r=0.884). However the BSAV was not affected by body weight, and had a better fit. Conclusion The BSAV method is recommended as a calibration method for thyroid volume in children.
- Children /
- Thyroid volume /
- Physical check /
- Correction index

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表 1 不同年龄儿童尿碘检测结果

Table 1. Urine iodine test results for children of different ages

年龄/岁 Age/years	检测例数 Number of detected cases	尿碘百分位数/% Urinary iodine percentile/%			尿碘频数分布/% Urinary iodine frequency distribution/%
年龄/岁 Age/years	检测例数 Number of detected cases	P₂₅	P₅₀	P₇₅	0~<50	50~<100	100~<200	200~<300	≥300
8	1 233	118.6	196.3	311.0	5.8	11.4	33.3	24.1	25.4
9	1 269	124.0	200.3	397.7	5.3	11.9	33.1	26.2	23.5
10	1 230	117.0	204.3	304.5	5.5	11.3	29.3	26.8	27.1
合计Total	3 732	124.5	201.3	301.4	5.5	11.5	31.9	25.8	25.3

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表 2 8~10岁儿童甲状腺容积正常值

Table 2. Normal value of thyroid volume in children aged 8-10 years

年龄/岁 Age/years	检测例数 Number of detected cases	M/mL	x/mL	P₉₇	国家标准/mL National standard/mL
8	1 233	2.40	2.47	3.88	4.50
9	1 269	2.67	2.77	4.40	5.00
10	1 230	3.06	3.22	5.34	6.00

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表 3 4种方法对年龄因素的校正

Table 3. Correction of age factors in four ways

年龄/岁 Age/years	检测例数 Number of detected cases	BMIV (x±s)	WHIV (x±s)	BSAV (x±s)	HVI (x±s)
8	1 233	1.53±0.50	0.68±0.20	2.46±0.70	1.46±0.40
9	1 269	1.69±1.60	0.67±0.80	2.61±2.50	1.55±1.50
10	1 230	1.85±0.60	0.64±0.20	2.71±0.80	1.61±0.50
H值value		214.943	18.469	74.157	64.161
P值value		<0.001	<0.001	<0.001	<0.001
注：BMIV, 体质容积指数; WHIV, 体重身高容积指数; BSAV, 体表面积容积指数; HVI, 身高容积指数。 Note: BMIV, body mass volume index; WHIV, weight height volume index; BSAV, body surface volume index; HVI, height volume index.

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参考文献(4)

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